Cefotaxime (claforan) - a third generation cephalosporin

Cefotaxime (Claforan) is a third-generation cephalosporin like Ceftriaxone that is used to treat the following bacterial infections:

  • Treatment of Bacteremia or Septicemia caused by:
    • Escherichia coli,
    • Klebsiella species,
    • Serratia marcescens,
    • Staphylococcus aureus and
    • Streptococcus species including Streptococcus pneumoniae.
  • Treatment of Bone and joint infections caused by:
    • Penicillinase and non-penicillinase producing strains of S. aureus,
    • Streptococcus species including Streptococcus pyogenes, and
    • Proteus mirabilis.
  • Treatment of CNS infections like meningitis and ventriculitis caused by:
    • Neisseria meningitidis,
    • Haemophilus influenzae,
    • S. pneumoniae,
    • Klebsiella pneumoniae,
    • E. coli.
  • Treatment of Genitourinary infections (including Urinary tract infections caused by:
    • Staphylococcus epidermidis,
    • Penicillinase and non-penicillinase producing S. aureus,
    • Citrobacter species,
    • Enterobacter species,
    • E. coli,
    • Klebsiella species,
    • P. mirabilis,
    • Proteus vulgaris,
    • Providencia stuartii,
    • Morganella morganii,
    • Providencia rettgeri, and
    • S. marcescens
  • Treatment of Gynecologic infections including pelvic inflammatory diseases caused by:
    • S. epidermidis,
    • Streptococcus species,
    • Enterobacter species,
    • Klebsiella species,
    • E. coli,
    • P. mirabilis,
    • Bacteroides species including Bacteroides fragilis
    • Clostridium species, and
    • Anaerobic cocci including Peptostreptococcus and Peptococcus species and
    • Fusobacterium species including Fusobacterium nucleatum
  • Treatment of Intraabdominal infections including peritonitis caused by:
    • Streptococcus species,
    • E. coli,
    • Klebsiella species,
    • Bacteroides species, and
    • anaerobic cocci including Peptostreptococcus species and Peptococcus species
    • P. mirabilis, and
    • Clostridium species.
  • Treatment of Lower respiratory tract infections including pneumonia caused by:
    • S. pneumoniae,
    • group A streptococci - S. pyogenes and other streptococci (except enterococci like Enterococcus faecalis
    • penicillinase and non-penicillinase producing S. aureus
    • E. coli,
    • Klebsiella species,
    • H. influenzae
    • H. parainfluenzae,
    • P. mirabilis,
    • S. marcescens,
    • Enterobacter species, and indole-positive Proteus
  • Treatment of Skin and soft tissue infections caused by:
    • penicillinase and non-penicillinase producing S. aureus,
    • S. epidermidis,
    • group A streptococci - S. pyogenes and other streptococci,
    • Acinetobacter species,
    • E. coli,
    • Citrobacter species,
    • Enterobacter species,
    • Klebsiella species,
    • P. mirabilis,
    • P. vulgaris,
    • M. morganii,
    • rettgeri,
    • S. marcescens,
    • Bacteroides species, and
    • anaerobic cocci including Peptostreptococcus species and Peptococcus species.
  • For the treatment of Surgical prophylaxis:
  • Off-Label Uses of cefotaxime in Adults include:
    • Acute bacterial rhinosinusitis
    • Animal Bite Wound
    • Disseminated Gonococcal infection including arthritis and arthritis-dermatitis syndrome
    • Lyme disease
    • Skin and soft tissue necrotizing infections

Cefotaxime Dose in Adults

Off-label use of Cefotaxime in treatment of severe Acute bacterial rhinosinusitis that necessitates hospitalization:

  • 2 g intravenous every 4 - 6 hours for 5 - 7 days.

Off label use of Cefotaxime in the treatment of animal Bite wound:

  • 1 to 2 g intravenous three or four times a day in combination with clindamycin or metronidazole for anaerobic coverage

Use of Cefotaxime in the empiric treatment of Brain abscess:

  • 2 gms intravenous four or six times a day in combination with other antimicrobials (like metronidazole)

Dose in patients undergoing a Cesarean section:

  • As soon as the umbilical chord is clamped, administer 1 g intravenously. Then, administer 1 gm intravenously or intramuscularly at 6 and 12 hours later.

Use of a different medication off-label to treat disseminated Gonorrhea infections, such as arthritis and the arthritis-dermatitis syndrome:

  • 1 gm intravenous thrice daily in combination with azithromycin for 24 to 48 hours. Oral antibiotics may replace IV ceftriaxone after improvement and according to susceptibility testing.
  • Treatment should be given for at least 7 days.

Use in the treatment of mild to moderate Intra abdominal community-acquired infection like a perforated appendix, diverticulitis, and intraabdominal abscess in the low-risk patient.

  • 2 gms intravenous thrice daily in combination with metronidazole for 4 to 7 days.
  • Oral therapy may replace IV therapy when the patient improves and is able to tolerate orally.
  • Some patients may require a longer duration of therapy.

Off-label use as an alternative agent for Lyme disease:

  • Cardiac manifestations:
    • 2 gms intravenous thrice daily for 14 - 21 days
  • Neurologic manifestations like meningitis and radiculopathy:
    • 2 gms intravenous thrice daily for 10 - 28 days.

Use in treatment of bacterial Meningitis:

  • 2 gms intravenous four to six times a day in combination with other appropriate antimicrobials when used as empiric therapy.

Use of Cefotaxime in the treatment of Community-acquired Pneumonia (CAP):

    • 1-2 gms intravenous thrice daily for 5 or more days.
    • In critical patients use in combination with azithromycin or a respiratory fluoroquinolone.
    • In non-critically, ill patients use in combination with a macrolide or doxycycline

Cefotaxime dose in the treatment of Sepsis:

    • 2 gms intravenous three to four times a day

Use in the treatment of Septic arthritis:

  • Neisseria gonorrhoeae:
    • 1 gm intravenous three times a day for 7 to 14 days in combination with a single dose of azithromycin
  • Susceptible gram-negative bacilli:
    • 2 gms intravenous three times a day for 3 to 4 weeks in the absence of osteomyelitis.

Off label use in the treatment of Skin and soft tissue necrotizing infections:

  • Polymicrobial infection:
    • For the initial treatment of polymicrobial infections, provide 2 gms intravenously four times per day in conjunction with clindamycin or metronidazole.
    • It should be continued until the patient improves, is afebrile for 48 to 72hours and further debridement is not necessary.
  • Necrotizing infection due to Vibrio vulnificus:
    • 2 gms intravenous thrice daily in combination with doxycycline.
    • It should be continued until the patient improves, is afebrile for 48 to 72hours and further debridement is not necessary.

Off label use in the treatment of Spontaneous bacterial peritonitis:

    • 2 gms intravenous thrice daily.

Off label use in the treatment of Surgical prophylaxis:

    • 1 gm intravenous one hour prior to the surgical incision.
    • The dose may be repeated in lengthy procedures (more than 3 hours or when excessive blood is lost)
    • Obese patients may be administered a dose of 2 gms one hour prior to the procedure.

Cefotaxime Dose in Children

General dosing of Cefotaxime in susceptible infection:

  • Infants, Children, and Adolescents:
    • 150 to 180 mg/kg/day intramuscular or intravenous in three divided doses to a maximum dose of 8 gms/day
    • Patients with meningitis may require a higher dose.

Use in treatment of severe Acute bacterial rhinosinusitis that necessitates hospitalization:

  • Children and Adolescents:
    • For a total dose of 2,000 mg, provide 100 to 200 mg/kg/day intravenously in four evenly spaced doses for 10 to 14 days.

Cefotaxime dose in the treatment of Endocarditis:

  • Children and Adolescents:
    • 200 mg/kg/day intravenous in four divided doses to a maximum dose of 12 g/day 4 to 6 weeks.
    • It may be used for a longer duration in some patients and may be combined with gentamicin for some organisms.

Use of cefotaxime in HIV positive or HIV exposed patients as empiric treatment for Enteric bacterial infections:

  • Adolescents:
    • 1,000 mg intravenous thrice daily

Use as an alternative to ceftriaxone in the treatment of disseminated Gonorrheal infection including arthritis and arthritis-dermatitis syndrome:

  • Adolescents:
    • 1,000 mg intravenous thrice daily in combination with azithromycin for at least 7 days.

Cefotaxim dose in the treatment of complicated Intra-abdominal infection:

  • Infants, Children, and Adolescents:
    • 150 to 200 mg/kg/day intravenous in three or four divided doses to a maximum dose of 2 gms in combination with metronidazole.

Use in treatment of Lyme disease (with cardiac manifestations, CNS manifestations or recurrent arthritis):

  • Infants, Children, and Adolescents:
    • 150 to 200 mg/kg/day intravenous in three or four divided doses for 14 - 28 days to a maximum daily dose of 6 g/day.

Cefotaxime dose in the treatment of Meningitis:

  • Infants, Children, and Adolescents:
    • 225 to 300 mg/kg/day intravenous three or four times a day to a maximum dose of 2 gms per dose.
    • Use vancomycin in conjunction with for empiric treatment.

Some professionals advise 300 mg/kg/day administered every four to six hours, with a daily dose cap of 12 g.


Use in treatment of Peritonitis in patients on peritoneal dialysis:

  • Infants, Children, and Adolescents:
    • Patients on intermittent peritoneal dialysis: 30 mg/kg/dose intraperitoneal once a day.
    • Patients on continuous peritoneal dialysis:
      • An intraperitoneal loading dose of 500 mg per liter of dialysate
      • maintenance dose of 250 mg per liter

Use of Cefotaxime in the treatment of Pneumonia:

  • Bacterial pneumonia in HIV-exposed or positive patients:
    • Infants, Children, and Adolescents:
      • 150 to 200 mg/kg/day intravenous in three or four divided doses to a maximum of 2 gms//dose
  • Community-acquired pneumonia (CAP):
    • Infants older than 3 months, Children, and Adolescents:
      • 50 mg/kg/dose intravenous thrice daily to a maximum dose of 2 gms.
      • The addition of vancomycin or clindamycin may be added as empiric therapy if community-acquired MRSA is suspected.
      • Macrolide antibiotics that cover the atypical organisms may be added in children older than 5 years of age

Use in the treatment of Salmonellosis in HIV-exposed or HIV- positive patients:


Use of Cefotaxime in the treatment of necrotizing Skin and soft tissue infections:

  • Infants, Children, and Adolescents:
    • 50 mg/kg/dose four times a day in combination with metronidazole or clindamycin to a maximum dose of 2 gms/dose.
    • It should be continued until the wound is healthy, the patient is afebrile for more than 48 to 72 hours and further debridement is not necessary.

Use of Cefotaxime in the treatment of Surgical prophylaxis:

  • Children and Adolescents:
    • 50 mg/kg intravenous one hour prior to the procedure. The dose may be repeated in the lengthy procedure (more than 3 hours)
    • The maximum recommended dose is 1 gm, however, obese patients may be given 2 gms.

Use of Cefotaxime in the treatment of Urinary tract infection:

  • Infants and Children 2 - 24 months of age:
    • 150 mg/kg/day IM or IV in three or four divided doses

 

Pregnancy Risk Factor B

  • Cefotaxime(Claforan).Crosses the placental boundary, but there have been no adverse drug reactions when taken during pregnancy.
  • It can be used by women who are having a cesarean section

Cefotaxime use during breastfeeding:

  • Cefotaxime can be found in breastmilk but is compatible with breastfeeding. It can alter the baby's bowel flora, and cause GI problems in the infant.

Cefotaxime Dose in Renal Disease:

 Renal dose adjustment according to the manufacturer:

  • CrCl of less than 20 mL/minute/1.73 m²: Reduce the dose by 50%. It is moderately dialyzable (20 - 50%)

Alternate recommendations for dose adjustment in patients with kidney disease:

  • GFR of more than 50 mL/minute: Administer the dose every 6 hours 
  • GFR of 10 - 50 mL/minute: Administer the dose twice daily
  • GFR of less than 10 mL/minute: Administer the dose once daily or reduce the dose by 50% at the usual recommended intervals
  • Patients on intermittent hemodialysis: Administer 1 - 2 gms once daily after hemodialysis
  • Patients on peritoneal dialysis: Administer 1 gm once daily
  • Patient with CVVH: 1 to 2 g twice or thrice daily
  • Patient with CVVHD: 1 to 2 g thrice daily
  • Patient with CVVHDF: 1 to 2 g three or four times a day.

Cefotaxime Dose in Liver Disease:

The manufacturer has not recommended any dose adjustment in patients with liver disease. 

Common Side Effects of Cefotaxime include:

  • Dermatologic:
    • Pruritus
    • Skin rash
  • Gastrointestinal:
    • Colitis
    • Diarrhea
    • Nausea
    • Vomiting
  • Hematologic & oncologic:
    • Eosinophilia
  • Local:
    • Induration at injection site
    • Inflammation at injection site
    • Pain at injection site
    • Tenderness at injection site
  • Miscellaneous:
    • Fever

Contraindications to Cefotaxime include:

  • Allergy reactions to cefotaxime or other cephalosporins or any component of this formulation

Warnings and Precautions​​​​​​​

  • Arrhythmia:
    • Rapid injections (less than one-minute) via a centralline can cause potentially life-threatening arrhythmia.
  • Granulocytopenia:
    • Cytopenias may develop if prolonged therapy is continued for more than 10 days. This could include granulocytopenia or life-threatening agranulocytosis.
  • Penicillin allergy
    • Patients who experience IgE-mediated responses like anaphylaxis, urticaria, or angioedema should use cefotaxime with caution.
  • Superinfection
    • Cefotaxime treatment for longer periods (over 2 months) can lead to superinfections, including fungal or bacterial superinfections. C. difficile-associated diarrhea, (CDAD), and pseudomembranous collitis can occur.
  • Local inflammation
    • Local site inflammation can occur at the injection/infusion site.
  • Colitis
    • Patients who have had colitis in the past should be cautious when taking this drug.
  • Renal impairment
    • Patients with kidney disease must be cautious when using the drug. The dose should also be adjusted.

Cefotaxime: Drug Interaction

Note: Drug Interaction Categories:

  • Risk Factor C: Monitor When Using Combination
  • Risk Factor D: Consider Treatment Modification
  • Risk Factor X: Avoid Concomitant Use

Risk Factor C (Monitor therapy).

Aminoglycosides Cephalosporins (3rd generation) can increase the nephrotoxic effects of Aminoglycosides.
BCG Vaccine (Immunization) Antibiotics can decrease the therapeutic effects of BCG Vaccine (Immunization).
Lactobacillus & Estriol Antibiotics can reduce the therapeutic effects of Lactobacillus or Estriol.
Vitamin K antagonists (eg warfarin) Cephalosporins can increase the anticoagulant effects of Vitamin K Antagonists.

Risk Factor D (Consider therapy modifications)

 
Probenecid There may be an increase in serum Cefotaxime concentrations. Management: When using a probenecid at the same time as cefotaxime, do not exceed 6 g/day. Patients receiving this combination should be carefully watched for any adverse effects of cefotaxime.
Sodium Picosulfate Antibiotics can reduce the therapeutic effects of Sodium Picosulfate. Patients who are currently using or have just finished using antibiotics should consider using an alternative product to cleanse the bowel prior to undergoing a colonoscopy.
Typhoid Vaccine The therapeutic effects of Typhoid vaccine may be diminished by antibiotics. The only affected strain is the live attenuated Ty21a. Patients being treated with systemic antibiotics should avoid vaccination with live attenuated Typhoid vaccine (Ty21a). This vaccine should not be used until at least three days after the cessation or discontinuation of antibacterial agent treatment.

Risk Factor X (Avoid Combination)

 
BCG (Intravesical). The therapeutic effects of BCG (Intravesical) may be diminished by antibiotics
Cholera Vaccine Cholera Vaccine may be less effective if taken with antibiotics. Treatment: Cholera vaccine should be avoided in patients who have received systemic antibiotics.

Monitoring Parameters:

  • Monitor the patient for features of anaphylaxis, especially after the first dose.
  • Monitor CBC with differential and renal functions especailly in patients on treatment for more than 10 days.

How to Administer Cefotaxime?

Intramuscular administration:

  • It should be injected deep into a large muscle. Larger doses may be divided and injected separately in different sites.

Intravenous administration:

  • It may be administered as an intravenous bolus over 3 - 5 minutes or as an infusion over 15 to 30 minutes.

Mechanism of action of Cefotaxime:

  • Cefotaxime blocks the formation of bacterial proteins, peptidoglycans and penicillin-binding proteins.
  • This eventually leads to cell lysis through the use of autolytic enzymes.
  • Both gramme positive and gramme negative bacteria that produce beta-lactamases, such as penicillinases and cephalosporinases, are susceptible to cefotaxime.
  • Bacteria may be naturally resistant to cefotaxime.
  • Additionally, the majority of isolates that produce carbapenemase and ESBL-producing bacteria are cefotaxime resistant.

It is widely availableTo body tissues and fluids such as aqueous humor, prostatic and ascitic fluids, bone and cerebrospinal liquid (especially when the meninges become inflamed).

The drug can be found in 31% to 50% of the marketProtein-boundIt is. It isMetabolizedPartly by the liver, and has ahalf-life elimination1. - 1.5 hours for adults and 1.5 hours for children. 3.4 and 4.6 hour respectively in infants weighing more than 1500gms and less that 1500gms, respectively. When peak serum is reachedThe average concentration of IM is 30 minutes. 60% of the drug is eliminated unchanged from the body.  

International Brands of Cefotaxime:

  • Claforan in D5W
  • Claforan
  • Benaxima
  • Biosint
  • Biotax
  • Cefacolin
  • Cefalekol
  • Cefocam
  • Ceforan
  • Cefot
  • Cefotaksim
  • Cefotax
  • Cefotaxim
  • Cefotrial
  • Cefox
  • Cefoxim
  • Cefpiran
  • Ceftax
  • Cetax
  • Clacef
  • Cladex
  • Clafocare
  • Claforan
  • Clafotax
  • Claraxim
  • Clavox
  • Diabec
  • Efotax
  • Fot-Amsa
  • Fotax
  • Fotexina
  • Foxime
  • Glocef
  • Gloryfen
  • Grifotaxima
  • Haxim
  • Lancef
  • Lapixime
  • Letynol
  • Loraxime
  • Lyforan
  • Makrocef
  • Newtaxime
  • Novatax
  • Omnatax
  • Oritaxim
  • Oritaxim-1000
  • Pantaxin
  • Pentatrox
  • Primocef
  • Prinocef
  • Procefa
  • Racotax
  • Ralopar
  • Reftax
  • Rekaxime
  • Saifulong
  • Sefotak
  • Soclaf
  • Spirosine
  • Stoparen
  • Talcef
  • Taporin
  • Tax-O-Bid
  • Taxibiotic
  • Taximax
  • Taxime
  • Taximed
  • Tebruxim
  • Tirdicef
  • Tirotax
  • Ultracef
  • Unitax
  • Viken
  • Xedin
  • Xendin
  • Ximvex
  • Xorin
  • Zariviz
  • Zefocent
  • Zefotax
  • Zentro
  • Zetax

Cefotaxime Brands in Pakistan:

Cefotaxime [Inj 1 g]

ADWOTEX BLOOM PHARMACEUTICALS (PVT) LTD.
AFRAN GENOME PHARMACEUTICALS (PVT) LTD
ALBAXIME ALBRO PHARMA
ALGIXIM EPHARM LABORATORIES
ALITOX ALLIANCE PHARMACEUTICALS (PVT) LTD.
ARATAXIME AR PHARMACEUTICALS
ASTETAXM ASTELLAS PHARMACEUTICALS
BACXIME SWISS PHARMACEUTICALS (PVT) LTD.
BAXIM NABIQASIM INDUSTRIES (PVT) LTD.
BIOLOG RAKAPOSHI PHARMACEUTICAL (PVT) LTD.
BIOTAXIME VALOR PHARMACEUTICALS
BIOXIM MEDICAIDS PAKISTAN (PVT) LTD.
BOSCEF LOWITT PHARMACEUTICALS (PVT) LTD
BREETEX PLIVA PAKISTAN (PVT) LIMITED
CAFRAN FYNK PHARMACEUTICALS
CEF-SO NEUTRO PHARMA (PVT) LTD.
CEFACRON GENESIS PHARMACEUTICALS (PVT) LTD.
CEFAX MASS PHARMA (PRIVATE) LIMITED
CEFCAN CANDID PHARMACEUTICALS
CEFDOX REX PHARMACEUTICALS PAKISTAN
CEFOCENT CENTURY PHARMACEUTICALS (PVT) LTD.
CEFOCIN JINNAH PHARMACEUTICALS
CEFOGATE LIBRA PHARMACEUTICALS (PVT) LTD
CEFOGREEN EVERGREEN PHARMACEUTICALS PVT LIMITED
CEFOMED MEDICRAFT PHARMACEUTICALS (PVT) LTD.
CEFOMERC MERCK PRIVATE LTD.
CEFON TABROS PHARMA
CEFORAINS MAC & RANS PHARMACEUTICALS (PVT) LTD
CEFORIN NAWAN LABORATORIES (PVT) LTD.
CEFOTAM REHMAN MEDICINE CO.
CEFOTAX BOSCH PHARMACEUTICALS (PVT) LTD.
CEFOTAXIME NOVARTIS PHARMA (PAK) LTD
CEFOXIM GEOFMAN PHARMACEUTICALS
CEFTAX ALBRO PHARMA
CEFTI CAYLEX PHARMACEUTICALS (PVT) LTD.
CEFTIFIXE SYNCHRO PHARMACEUTICALS
CEFTIM DRUGS INN PAKISTAN
CEFTISAV MEDISAVE PHARMACEUTICALS
CEFTORINGE CONSOLIDATED CHEMICAL LABORATORIES (PVT) LTD.
CEFTREX POLYFINE CHEMPHARMA (PVT) LTD.
CEFWISE PHARMAWISE LABS. (PVT) LTD.
CEMETAX CREST PHARMACEUTICALS
CEPHRONATE P.D.H. PHARMACEUTICALS (PVT) LTD.
CEUTICSAXIME UN PHARMA INTERNATIONAL
CLAFORAN SANOFI AVENTIS (PAKISTAN) LTD.
CLAFTAX DR. RAZA PHARMA (PRIVATE) LIMITED
CLAGEN EPOCH PHARMACEUTICAL
CLAVOX MACTER INTERNATIONAL (PVT) LTD.
CLIFRID MEDERA PHARMACEUTICALS (PVT) LTD.
CLIVER Shaigan Pharmaceuticals (PVT) LTD
CYNOTAX UNISON CHEMICAL WORKS
CYOX RAAZEE THERAPUTICS (PVT) LTD.
D-FRON DRUG PHARM (PVT) LTD.
DORTIS WISE PHARMACEUTICALS (PVT) LTD
EAXIRON ENGLISH PHARMACEUTICALS INDUSTRIES
EFIXONE SHAWAN PHARMACEUTICALS
ELKOTAX ELKO ORGANIZATION (PVT) LTD.
EMEXIN Z-JANS PHARMACEUTICAL (PVT) LTD.
EPOTAZIME EPOCH PHARMACEUTICAL
EVOTAXIME PHARMEVO (PVT) LTD.
EXEF INDUS PHARMA (PVT) LTD.
FARAXIME ELITE PHARMA
FASTIMAX S.J. & G. FAZUL ELLAHIE (PVT) LTD.
FEDRATOX FEDRO PHARMACEUTICAL
FORAX AMSON VACCINES & PHARMA (PVT) LTD.
FOTAMAK MAKSON PHARMACEUTICALS
FOTAX CIRIN PHARMACEUTICALS (PVT) LTD.
FOXIME HAMAZ PHARMACEUTICAL (PVT) LTD.
FURITAX STANDPHARM PAKISTAN (PVT) LTD.
FUSTEXIN NEOPHAR HEALTH-CARE
GEN-3 SHROOQ PHARMACEUTICALS
GENCEF DRUGS INN PAKISTAN
GRAXIME QINTAR PHARMACUTICALS
HEXIME ALINA COMBINE PHARMACEUTICALS (PVT) LTD.
HYLAFORM CARAWAY PHARMACEUTICALS
HYPERTAX IPRAM INTERNATIONAL
INSTAX MEDITECH PHARMACEUTICALS
IXIM PHARMATEC PAKISTAN (PVT) LTD.
JAFOTAX JAWA PHARMACEUTICALS(PVT) LTD.
KALFOXIM SHAFAZ PHARMA INTERNATIONAL (PVT) LTD.
KC-TEX KARACHI CHEMICAL INDUSTRIES
KECEF ARIES PHARMACEUTICALS (PVT) LTD
KEPREX KINGS PHARMACEUTICALS
KUMAND ENVOY PHARMA
L-FOTAX LEAMA CHEMI PHARMA (PVT.) LTD.
LIFTAX LINEAR PHARMA
MACFRAN MACQUINS INTERNATIONAL
MAHIR AMBROSIA PHARMACEUTICALS
MB-CEF MULTINATIONAL BUISNESS LINK
MEDFOTAX WELMED PHARMACEUTICALS INDUSTRIES (PVT) LTD
MEDIFRAN MEDIATE PHARMACEUTICALS (PVT) LTD
MOLELANT MEEZAB INTERNATIONAL
MYTAX HICON PHARMACEUTICALS
N-ZEE NENZA PHARMACEUTICALS (PVT) LIMITED
N-ZONE NENZA PHARMACEUTICALS (PVT) LIMITED
NAWOTAX NAWAN LABORATORIES (PVT) LTD.
NEATX SPADIX PHARMACEUTICALS
NESTOX VISION PHARMACUETICALS
NITAXIM NEXUS PHARMA (PVT) LTD
NOSPOR KARACHI PHARMACEUTICAL LABORATORY
NOVATEX ZESION PHARMACEUTICAL (PVT) LTD
NOVOSEF HIMONT PHARMACEUTICALS (PVT) LTD.
OBIXIME OBSONS PHARMACEUTICALS
OCECLAF SAFE PHARMACEUTICAL (PVT) LTD.
OLSON MCOLSON RESEARCH LABORATORIES
ONEXIN AKSON PHARMACEUTICALS (PVT) LTD.
ORTAXIME ORTA LABS. (PVT) LTD.
PCEF PEARL PHARMACEUTICALS
PERT W & ALI SONS PHARMACEUTICALS
POLYTAX POLYFINE CHEMPHARMA (PVT) LTD.
PULCEF PULSE PHARMACEUTICALS
PURE-XEM NOVA MED PHARMACEUTICALS
QCEF BIOSYNTH PHARMA (PVT) LTD.
RACLIF ARDIN PHARMACEUTICALS
RIEL WEBROS PHARMACEUTICALS
ROCETRAX STAR LABORATORIES (PVT) LTD.
SAJTOX NEUTRO PHARMA (PVT) LTD.
SAMCEF FERROZA INTERNATIONAL PHARMACEUTICALS (PVT) LTD.
SEFOBAN HIMONT PHARMACEUTICALS (PVT) LTD.
SETEX MEDIAIMS PHARMACEUTICALS
SHINTAX MEDISURE LABORATORIES PAKISTAN (PVT.) LTD.
SILVAXIME SILVER OAK CORPORATION.
SPEEDRO DANAS PHARMACEUTICALS (PVT) LTD
SPIROSINE NOBLE PHARMA
SPORONIL GLOBAL PHARMACEUTICALS
SPORTAX BREEZE PHARMA (PVT) LTD
STAFRON STAR LABORATORIES (PVT) LTD.
SUNTAC HISUN PHARMACEUTICALS
SUPRAX MEDICEENA PHARMA (PVT) LTD.
SURGITEC SURGE LABORATORIES (PVT) LTD.
SWIFTAX WILSHIRE LABORATORIES (PVT) LTD.
TACZIN WELLBORNE PHARMACHEM AND BIOLOGICALS
TAXFO GOODMAN INTERNATIONAL,
TAXIBEN BENSON PHARAMCEUTICALS.
TAXIME AKHAI PHARMACEUTICALS.
TAXIRON PHARMEDIC (PVT) LTD.
TRAXIM BIO LABS (PVT) LTD.
TRAXIM BIO LABS (PVT) LTD.
TREAT VISION PHARMACUETICALS
TRIGOREN TRIGON PHARMACEUTICALS PAKISTAN (PVT) LTD.
TUFZONE PULSE PHARMACEUTICALS
UNEED ROBINS PHARMACEUTICAL INDUSTRIES
UNITOXIME TG PHARMA
VEGACEFT VEGA PHARMACEUTICALS LTD.
VICOFRON UNI-TECH PHARMACEUTICALS (PVT) LTD
WINTAX BARRETT HODGSON PAKISTAN (PVT) LTD.
WITAX BIOREX PHARMACEUTICALS
WONTAXIME BIO PHARMA
XEMEG MEGA PHARMACEUTICALS (PVT) LTD
XIMGAL GLOBAL PHARMACEUTICALS
YORKER SAMI PHARMACEUTICALS (PVT) LTD.
ZAFIXIME ZAFA PHARMACEUTICAL LABORATORIES (PVT) LTD.
ZEREF-S LLOYDS PHARMACEUTICALS
ZINTAXIME ZINTA PHARMACEUTICALS INDUSTRIES
ZYMACEF SHAWAN PHARMACEUTICALS

Cefotaxime [Inj 2 g]

CLAFORAN SANOFI AVENTIS (PAKISTAN) LTD.
KALFOXIM SHAFAZ PHARMA INTERNATIONAL (PVT) LTD.
SUPRAX MEDICEENA PHARMA (PVT) LTD.

Cefotaxime [Inj 1 gm]

FUSTEXIM GLOBAL PHARMACEUTICALS

Cefotaxime [Inj 125 mg]

TAXIRON PHARMEDIC (PVT) LTD.

Cefotaxime [Inj 250 mg]

ADWOTEX BLOOM PHARMACEUTICALS (PVT) LTD.
AFRAN GENOME PHARMACEUTICALS (PVT) LTD
ALBAXIM ALBRO PHARMA
ALBAXIME ALBRO PHARMA
ALGIXIM EPHARM LABORATORIES
ALITOX ALLIANCE PHARMACEUTICALS (PVT) LTD.
ARATAXIME AR PHARMACEUTICALS
ASTETAXM ASTELLAS PHARMACEUTICALS
AWABROD USAWA PHARMACEUTICALS
AXIFINE DAVIS PHARMACEUTICAL LABORATORIES
BACXIME SWISS PHARMACEUTICALS (PVT) LTD.
BAXFORAN Baxter Karachi
BAXIM NABIQASIM INDUSTRIES (PVT) LTD.
BIOLOG RAKAPOSHI PHARMACEUTICAL (PVT) LTD.
BIOTAXIME VALOR PHARMACEUTICALS
BIOXIM MEDICAIDS PAKISTAN (PVT) LTD.
BOSCEF LOWITT PHARMACEUTICALS (PVT) LTD
BREETEX PLIVA PAKISTAN (PVT) LIMITED
CAFRAN FYNK PHARMACEUTICALS
CEF-SO NEUTRO PHARMA (PVT) LTD.
CEFACRON GENESIS PHARMACEUTICALS (PVT) LTD.
CEFAX MASS PHARMA (PRIVATE) LIMITED
CEFCAN CANDID PHARMACEUTICALS
CEFDOX REX PHARMACEUTICALS PAKISTAN
CEFOCENT CENTURY PHARMACEUTICALS (PVT) LTD.
CEFOCIN JINNAH PHARMACEUTICALS
CEFOGATE LIBRA PHARMACEUTICALS (PVT) LTD
CEFOGREEN EVERGREEN PHARMACEUTICALS PVT LIMITED
CEFOMED MEDICRAFT PHARMACEUTICALS (PVT) LTD.
CEFOMERC MERCK PRIVATE LTD.
CEFON TABROS PHARMA
CEFORAINS MAC & RANS PHARMACEUTICALS (PVT) LTD
CEFORIN NAWAN LABORATORIES (PVT) LTD.
CEFOTAM REHMAN MEDICINE CO.
CEFOTAX BOSCH PHARMACEUTICALS (PVT) LTD.
CEFOXIM GEOFMAN PHARMACEUTICALS
CEFTI CAYLEX PHARMACEUTICALS (PVT) LTD.
CEFTIM DRUGS INN PAKISTAN
CEFTISAV MEDISAVE PHARMACEUTICALS
CEFTORINGE CONSOLIDATED CHEMICAL LABORATORIES (PVT) LTD.
CEFTREX POLYFINE CHEMPHARMA (PVT) LTD.
CEFWISE PHARMAWISE LABS. (PVT) LTD.
CEMETAX CREST PHARMACEUTICALS
CEPHRONATE P.D.H. PHARMACEUTICALS (PVT) LTD.
CEUTICSAXIME UN PHARMA INTERNATIONAL
CLAFORAN SANOFI AVENTIS (PAKISTAN) LTD.
CLAFTAX DR. RAZA PHARMA (PRIVATE) LIMITED
CLAGEN EPOCH PHARMACEUTICAL
CLAVOX MACTER INTERNATIONAL (PVT) LTD.
CLIFRID MEDERA PHARMACEUTICALS (PVT) LTD.
CLIVER Shaigan Pharmaceuticals (PVT) LTD
CYNOTAX UNISON CHEMICAL WORKS
CYOX RAAZEE THERAPUTICS (PVT) LTD.
D-FRON DRUG PHARM (PVT) LTD.
DORTIS WISE PHARMACEUTICALS (PVT) LTD
EAXIRON ENGLISH PHARMACEUTICALS INDUSTRIES
EFIXONE SHAWAN PHARMACEUTICALS
ELKOTAX ELKO ORGANIZATION (PVT) LTD.
EMEXIN Z-JANS PHARMACEUTICAL (PVT) LTD.
EPOTAZIME EPOCH PHARMACEUTICAL
EVOTAXIME PHARMEVO (PVT) LTD.
EXEF INDUS PHARMA (PVT) LTD.
FARAXIME ELITE PHARMA
FASTIMAX S.J. & G. FAZUL ELLAHIE (PVT) LTD.
FEDRATOX FEDRO PHARMACEUTICAL
FORAX AMSON VACCINES & PHARMA (PVT) LTD.
FOTAMAK MAKSON PHARMACEUTICALS
FOTAX CIRIN PHARMACEUTICALS (PVT) LTD.
FOXIME HAMAZ PHARMACEUTICAL (PVT) LTD.
FURITAX STANDPHARM PAKISTAN (PVT) LTD.
GEN-3 SHROOQ PHARMACEUTICALS
GENEXIME BIOGEN PHARMA
GRAXIME QINTAR PHARMACUTICALS
HEXIME ALINA COMBINE PHARMACEUTICALS (PVT) LTD.
HYLAFORM CARAWAY PHARMACEUTICALS
HYPERTAX IPRAM INTERNATIONAL
INSTAX MEDITECH PHARMACEUTICALS
IXIM PHARMATEC PAKISTAN (PVT) LTD.
JAFOTAX JAWA PHARMACEUTICALS(PVT) LTD.
KALFOXIM SHAFAZ PHARMA INTERNATIONAL (PVT) LTD.
KC-TEX KARACHI CHEMICAL INDUSTRIES
KECEF ARIES PHARMACEUTICALS (PVT) LTD
KEPREX KINGS PHARMACEUTICALS
KUMAND ENVOY PHARMA
L-FOTAX LEAMA CHEMI PHARMA (PVT.) LTD.
LIFTAX LINEAR PHARMA
MACFRAN MACQUINS INTERNATIONAL
MAHIR AMBROSIA PHARMACEUTICALS
MB-CEF MULTINATIONAL BUISNESS LINK
MEDFOTAX WELMED PHARMACEUTICALS INDUSTRIES (PVT) LTD
MEDIFRAN MEDIATE PHARMACEUTICALS (PVT) LTD
MOLELANT MEEZAB INTERNATIONAL
MYTAX HICON PHARMACEUTICALS
N-ZEE NENZA PHARMACEUTICALS (PVT) LIMITED
N-ZONE NENZA PHARMACEUTICALS (PVT) LIMITED
NEATX SPADIX PHARMACEUTICALS
NESTOX VISION PHARMACUETICALS
NITAXIM NEXUS PHARMA (PVT) LTD
NOSPOR KARACHI PHARMACEUTICAL LABORATORY
NOVATEX ZESION PHARMACEUTICAL (PVT) LTD
NOVOSEF HIMONT PHARMACEUTICALS (PVT) LTD.
OBIXIME OBSONS PHARMACEUTICALS
OCECLAF SAFE PHARMACEUTICAL (PVT) LTD.
OLSON MCOLSON RESEARCH LABORATORIES
ONEXIN AKSON PHARMACEUTICALS (PVT) LTD.
ORTAXIME ORTA LABS. (PVT) LTD.
PCEF PEARL PHARMACEUTICALS
PERT W & ALI SONS PHARMACEUTICALS
POLYTAX POLYFINE CHEMPHARMA (PVT) LTD.
PULCEF PULSE PHARMACEUTICALS
PURE-XEM NOVA MED PHARMACEUTICALS
QCEF BIOSYNTH PHARMA (PVT) LTD.
RACLIF ARDIN PHARMACEUTICALS
RIEL WEBROS PHARMACEUTICALS
RITAGE BRYON PHARMACEUTICALS (PVT) LTD.
ROCETRAX STAR LABORATORIES (PVT) LTD.
SAJTOX NEUTRO PHARMA (PVT) LTD.
SAMCEF FERROZA INTERNATIONAL PHARMACEUTICALS (PVT) LTD.
SEFOBAN HIMONT PHARMACEUTICALS (PVT) LTD.
SETEX MEDIAIMS PHARMACEUTICALS
SHIFACRON SHIFA LABORATORIES.(PVT) LTD.
SILVAXIME SILVER OAK CORPORATION.
SPEEDRO DANAS PHARMACEUTICALS (PVT) LTD
SPORONIL GLOBAL PHARMACEUTICALS
SPORTAX BREEZE PHARMA (PVT) LTD
STAFRON STAR LABORATORIES (PVT) LTD.
SUNTAC HISUN PHARMACEUTICALS
SUPRAX MEDICEENA PHARMA (PVT) LTD.
SURGITEC SURGE LABORATORIES (PVT) LTD.
SWIFTAX WILSHIRE LABORATORIES (PVT) LTD.
TACZIN WELLBORNE PHARMACHEM AND BIOLOGICALS
TAXFO GOODMAN INTERNATIONAL,
TAXIBEN BENSON PHARAMCEUTICALS.
TAXIME AKHAI PHARMACEUTICALS.
TAXIRON PHARMEDIC (PVT) LTD.
TRENCH HANSEL PHARMACUEUTICAL PVT (LTD)
TRIGOREN TRIGON PHARMACEUTICALS PAKISTAN (PVT) LTD.
TUFZONE PULSE PHARMACEUTICALS
UNITOXIME TG PHARMA
VEGACEFT VEGA PHARMACEUTICALS LTD.
VICOFRON UNI-TECH PHARMACEUTICALS (PVT) LTD
WINTAX BARRETT HODGSON PAKISTAN (PVT) LTD.
WITAX BIOREX PHARMACEUTICALS
WONTAXIME BIO PHARMA
XEMEG MEGA PHARMACEUTICALS (PVT) LTD
XIMGAL GLOBAL PHARMACEUTICALS
YORKER SAMI PHARMACEUTICALS (PVT) LTD.
ZAFIXIME ZAFA PHARMACEUTICAL LABORATORIES (PVT) LTD.
ZEREF-S LLOYDS PHARMACEUTICALS
ZINTAXIME ZINTA PHARMACEUTICALS INDUSTRIES
ZYMACEF SHAWAN PHARMACEUTICALS

Cefotaxime [Inj 500 mg]

ADWOTEX BLOOM PHARMACEUTICALS (PVT) LTD.
AFRAN GENOME PHARMACEUTICALS (PVT) LTD
ALBAXIME ALBRO PHARMA
ALGIXIM EPHARM LABORATORIES
ALITOX ALLIANCE PHARMACEUTICALS (PVT) LTD.
ARATAXIME AR PHARMACEUTICALS
ASTETAXM ASTELLAS PHARMACEUTICALS
AWABROD USAWA PHARMACEUTICALS
AXIFINE DAVIS PHARMACEUTICAL LABORATORIES
BACXIME SWISS PHARMACEUTICALS (PVT) LTD.
BAXFORAN Baxter Karachi
BAXIM NABIQASIM INDUSTRIES (PVT) LTD.
BIDZIME AHAD INTERNATIONAL PHARMACEUTICALS
BIOLOG RAKAPOSHI PHARMACEUTICAL (PVT) LTD.
BIOXIM MEDICAIDS PAKISTAN (PVT) LTD.
BOSCEF LOWITT PHARMACEUTICALS (PVT) LTD
BREETEX PLIVA PAKISTAN (PVT) LIMITED
CAFRAN FYNK PHARMACEUTICALS
CEF-SO NEUTRO PHARMA (PVT) LTD.
CEFACRON GENESIS PHARMACEUTICALS (PVT) LTD.
CEFCAN CANDID PHARMACEUTICALS
CEFDOX REX PHARMACEUTICALS PAKISTAN
CEFOCENT CENTURY PHARMACEUTICALS (PVT) LTD.
CEFOCIN JINNAH PHARMACEUTICALS
CEFOGATE LIBRA PHARMACEUTICALS (PVT) LTD
CEFOGREEN EVERGREEN PHARMACEUTICALS PVT LIMITED
CEFOMED MEDICRAFT PHARMACEUTICALS (PVT) LTD.
CEFOMERC MERCK PRIVATE LTD.
CEFON TABROS PHARMA
CEFORAINS MAC & RANS PHARMACEUTICALS (PVT) LTD
CEFORIN NAWAN LABORATORIES (PVT) LTD.
CEFOTAX BOSCH PHARMACEUTICALS (PVT) LTD.
CEFOXIM GEOFMAN PHARMACEUTICALS
CEFTI CAYLEX PHARMACEUTICALS (PVT) LTD.
CEFTIM DRUGS INN PAKISTAN
CEFTISAV MEDISAVE PHARMACEUTICALS
CEFTREX POLYFINE CHEMPHARMA (PVT) LTD.
CEFWISE PHARMAWISE LABS. (PVT) LTD.
CEMETAX CREST PHARMACEUTICALS
CEPHRONATE P.D.H. PHARMACEUTICALS (PVT) LTD.
CEUTICSAXIME UN PHARMA INTERNATIONAL
CLAFORAN SANOFI AVENTIS (PAKISTAN) LTD.
CLAFTAX DR. RAZA PHARMA (PRIVATE) LIMITED
CLAGEN EPOCH PHARMACEUTICAL
CLAVOX MACTER INTERNATIONAL (PVT) LTD.
CLIVER Shaigan Pharmaceuticals (PVT) LTD
CYOX RAAZEE THERAPUTICS (PVT) LTD.
D-FRON DRUG PHARM (PVT) LTD.
DORTIS WISE PHARMACEUTICALS (PVT) LTD
EAXIRON ENGLISH PHARMACEUTICALS INDUSTRIES
EFIXONE SHAWAN PHARMACEUTICALS
ELKOTAX ELKO ORGANIZATION (PVT) LTD.
EMEXIN Z-JANS PHARMACEUTICAL (PVT) LTD.
EPOTAZIME EPOCH PHARMACEUTICAL
EVOTAXIME PHARMEVO (PVT) LTD.
EXEF INDUS PHARMA (PVT) LTD.
FARAXIME ELITE PHARMA
FASTIMAX S.J. & G. FAZUL ELLAHIE (PVT) LTD.
FEDRATOX FEDRO PHARMACEUTICAL
FORAX AMSON VACCINES & PHARMA (PVT) LTD.
FOTAMAK MAKSON PHARMACEUTICALS
FOTAX CIRIN PHARMACEUTICALS (PVT) LTD.
FOXIME HAMAZ PHARMACEUTICAL (PVT) LTD.
FURITAX STANDPHARM PAKISTAN (PVT) LTD.
FUSTEXIM GLOBAL PHARMACEUTICALS
FUSTEXIN NEOPHAR HEALTH-CARE
GEN-3 SHROOQ PHARMACEUTICALS
GENEXIME BIOGEN PHARMA
HEXIME ALINA COMBINE PHARMACEUTICALS (PVT) LTD.
HYLAFORM CARAWAY PHARMACEUTICALS
HYPERTAX IPRAM INTERNATIONAL
INSTAX MEDITECH PHARMACEUTICALS
IXIM PHARMATEC PAKISTAN (PVT) LTD.
KALFOXIM SHAFAZ PHARMA INTERNATIONAL (PVT) LTD.
KC-TEX KARACHI CHEMICAL INDUSTRIES
KECEF ARIES PHARMACEUTICALS (PVT) LTD
KEPREX KINGS PHARMACEUTICALS
KUMAND ENVOY PHARMA
L-FOTAX LEAMA CHEMI PHARMA (PVT.) LTD.
LIFTAX LINEAR PHARMA
MACFRAN MACQUINS INTERNATIONAL
MAHIR AMBROSIA PHARMACEUTICALS
MB-CEF MULTINATIONAL BUISNESS LINK
MEDFOTAX WELMED PHARMACEUTICALS INDUSTRIES (PVT) LTD
MEDIFRAN MEDIATE PHARMACEUTICALS (PVT) LTD
MOLELANT MEEZAB INTERNATIONAL
MYTAX HICON PHARMACEUTICALS
N-ZEE NENZA PHARMACEUTICALS (PVT) LIMITED
N-ZONE NENZA PHARMACEUTICALS (PVT) LIMITED
NEATX SPADIX PHARMACEUTICALS
NESTOX VISION PHARMACUETICALS
NITAXIM NEXUS PHARMA (PVT) LTD
NOSPOR KARACHI PHARMACEUTICAL LABORATORY
NOVATEX ZESION PHARMACEUTICAL (PVT) LTD
NOVOSEF HIMONT PHARMACEUTICALS (PVT) LTD.
OBIXIME OBSONS PHARMACEUTICALS
OLSON MCOLSON RESEARCH LABORATORIES
ONEXIN AKSON PHARMACEUTICALS (PVT) LTD.
ORTAXIME ORTA LABS. (PVT) LTD.
PCEF PEARL PHARMACEUTICALS
PERT W & ALI SONS PHARMACEUTICALS
POLYTAX POLYFINE CHEMPHARMA (PVT) LTD.
PULCEF PULSE PHARMACEUTICALS
PURE-XEM NOVA MED PHARMACEUTICALS
QCEF BIOSYNTH PHARMA (PVT) LTD.
RACLIF ARDIN PHARMACEUTICALS
RIEL WEBROS PHARMACEUTICALS
RITAGE BRYON PHARMACEUTICALS (PVT) LTD.
ROCETRAX STAR LABORATORIES (PVT) LTD.
SAJTOX NEUTRO PHARMA (PVT) LTD.
SAMCEF FERROZA INTERNATIONAL PHARMACEUTICALS (PVT) LTD.
SEFOBAN HIMONT PHARMACEUTICALS (PVT) LTD.
SETEX MEDIAIMS PHARMACEUTICALS
SHIFACRON SHIFA LABORATORIES.(PVT) LTD.
SILVAXIME SILVER OAK CORPORATION.
SPEEDRO DANAS PHARMACEUTICALS (PVT) LTD
SPORONIL GLOBAL PHARMACEUTICALS
STAFRON STAR LABORATORIES (PVT) LTD.
SUNTAC HISUN PHARMACEUTICALS
SUPRAX MEDICEENA PHARMA (PVT) LTD.
SURGITEC SURGE LABORATORIES (PVT) LTD.
SWIFTAX WILSHIRE LABORATORIES (PVT) LTD.
TACZIN WELLBORNE PHARMACHEM AND BIOLOGICALS
TAXFO GOODMAN INTERNATIONAL,
TAXIBEN BENSON PHARAMCEUTICALS.
TAXIME AKHAI PHARMACEUTICALS.
TAXIRON PHARMEDIC (PVT) LTD.
TRAXIM BIO LABS (PVT) LTD.
TRAXIM BIO LABS (PVT) LTD.
TRENCH HANSEL PHARMACUEUTICAL PVT (LTD)
TUFZONE PULSE PHARMACEUTICALS
UNITOXIME TG PHARMA
VEGACEFT VEGA PHARMACEUTICALS LTD.
VICOFRON UNI-TECH PHARMACEUTICALS (PVT) LTD
WINTAX BARRETT HODGSON PAKISTAN (PVT) LTD.
WITAX BIOREX PHARMACEUTICALS
WONTAXIME BIO PHARMA
YORKER SAMI PHARMACEUTICALS (PVT) LTD.
ZAFIXIME ZAFA PHARMACEUTICAL LABORATORIES (PVT) LTD.
ZEREF-S LLOYDS PHARMACEUTICALS
ZINTAXIME ZINTA PHARMACEUTICALS INDUSTRIES
ZYMACEF SHAWAN PHARMACEUTICALS

Cefotaxime [Inj-IV 1 g]

FOTRI FOZAN PHARMACEUTICALS INDUSTRIERS (PVT) LTD
NOVOSEF HIMONT PHARMACEUTICALS (PVT) LTD.
SAMCEF FERROZA INTERNATIONAL PHARMACEUTICALS (PVT) LTD.

Cefotaxime [Inj-IV 250 mg]

FOTRI FOZAN PHARMACEUTICALS INDUSTRIERS (PVT) LTD
NOVOSEF HIMONT PHARMACEUTICALS (PVT) LTD.
SAMCEF FERROZA INTERNATIONAL PHARMACEUTICALS (PVT) LTD.

Cefotaxime [Inj-IV 500 mg]

FOTRI FOZAN PHARMACEUTICALS INDUSTRIERS (PVT) LTD
NOVOSEF HIMONT PHARMACEUTICALS (PVT) LTD.
SAMCEF FERROZA INTERNATIONAL PHARMACEUTICALS (PVT) LTD.

Cefotaxime [Inhaler 1 g]

CEFABEST EG PHARMACEUTICALS

Cefotaxime [Inhaler 250 mg]

CEFABEST EG PHARMACEUTICALS

Cefotaxime [Inhaler 500 mg]

CEFABEST EG PHARMACEUTICALS

Cefotaxime [Susp 100 mg/5ml]

SUPERIXIME BIOREX PHARMACEUTICALS

Cefotaxime [Caps 1 g]

MEDOXIN GRAY`S PHARMACEUTICALS

Cefotaxime [Caps 250 mg]

MEDOXIN GRAY`S PHARMACEUTICALS

Cefotaxime [Caps 500 mg]

MEDOXIN GRAY`S PHARMACEUTICALS