Cetirizine (Zyrtec, Sunizine) for Flu and Allergies

Cetirizine (Zyrtec, sunizine) inhibits histamine receptors present in the skin, gastrointestinal tract and blood vessels. It is used to treat patients with the following conditions:

  • Itching due to urticaria and allergic symptoms of the respiratory tract.

Off-Label Uses of Cetirizine in Adults include

  • Anaphylaxis
  • Acute allergic and recurrent angioedema
  • Reactions due to intravenous medications

Cetirizine (Zyrtec) dose in Adults

Cetirizine (Zyrtec) dose in Allergic rhinitis (runny nose) and conjunctivitis:


For symptoms of hay fever or other upper respiratory allergies as OTC drug:

  • 5 to 10 mg once daily to a maximum dose of 10 mg/day.

Off label use of Cetirizine in the treatment of Anaphylaxis as an adjunct to epinephrine for the relief of cutaneous symptoms:

Note: Cetirizine should not be used as monotherapy. It is also not effective in patients with shock and in relieving lower respiratory tract symptoms.

  • 10 mg as a single dose

  •  Off-label use of Cetirizine in the treatment of acute allergic and  recurrent idiopathic Angioedema:  

Note: It is not indicated for angioedema with anaphylaxis as it is not effective in the treatment of hypotension and symptoms of lower airway obstruction. 

  • 10 mg once or two times a day to a maximum dose of 20 mg twice daily

  • Off label use for premedication as an alternative agent in the treatment of Infusion reaction:

    • 10 mg administered 30 - 60 minutes before the infusion of certain chemotherapy agents and biologics.

  • Use of Cetirizine in the treatment of acute and chronic spontaneous Urticaria:

    • 10 mg once daily initially, the dose may be increased in increments of 10 mg every 1- 4 weeks to a maximum dose of 20 mg twice daily if the symptoms are not controlled.

Cetirizine (Zyrtec) dose in Children

Use of Cetirizine in the treatment of Chronic urticaria in children: 

  • Infants 6 - 12 months of age:

    • 2.5 mg once daily
  • Children 12 - 23 months of age:

    • 2.5 mg once daily initially to a maximum dose of 2.5 mg twice daily
  • Children 2 - 5 years of age:

    • 2.5 mg once daily to a maximum dose of 2.5 mg twice daily or 5 mg once daily

Use of Cetirizine in the treatment of Allergic rhinitis:

  • Infants 6 - 12 months of age:

    • 2.5 mg once daily
  • Children 12 - 23 months of age:

    • 2.5 mg once daily initially to a maximum dose of 2.5 mg twice daily

Use of Cetirizine in the treatment of hay fever and other Allergic symptoms:

  • Children 2 - 5 years of age:

    • 2.5 mg once daily to a maximum dose of 2.5 mg twice daily or 5 mg once daily
  • Children older than 6 years and Adolescents:

    • 5 to 10 mg once a day.

Pregnancy Risk Factor B

  • Cetirizine can be used to relieve allergic symptoms in pregnant women. However, it is best to use the lowest dose.

Cetirizine use during Breastfeeding:

  • Breastmilk is enriched with cetirizine.
  • Because of its less sedative effects, a second-generation antihistamine might be preferable to the first.
  • However, infants should be monitored for irritability and drowsiness.
  • Cetirizine can also reduce prolactin secretion, which may cause an increase in milk production in lactating mothers.

Cetirizine (Zyrtec) dose in Renal Disease:

The manufacturer has not recommended any dose adjustment in patients with renal disease, however, the following guidelines may be followed:

  • GFR of more than 50 mL/minute:

    • No adjustment in the dose is required
  • GFR of less than 50 mL/minute:

    • 5 mg once a day.
  • Intermittent hemodialysis:

    • 5 mg once a day or three times a week
  • Peritoneal dialysis:

    • 5 mg once a day.

Cetirizine (Zyrtec) dose in Liver Disease:

  • The manufacturer has not recommended any dose adjustment in patients with liver disease.
  • Because of its sedating properties, it should be used with caution in advanced liver disease.

Common Side Effects of Cetirizine:

  • Central nervous system:
    • Drowsiness
    • Headache

Less Common Side Effects of Cetirizine include:

  • Central nervous system:
    • Insomnia
    • Fatigue
    • Malaise
    • Dizziness
  • Gastrointestinal:
    • Abdominal pain
    • Xerostomia
    • Diarrhea
    • Nausea
    • Vomiting
  • Respiratory:
    • Pharyngitis
    • Epistaxis
    • Bronchospasm

Contraindications to Cetirizine:

Allergy or sensitivity to cetirizine, hydrazine, or any other component of the formulation

Warnings and Precautions

  • CNS depression:
    • Patients who are using heavy machinery or those who need mental alertness such as driving should use it with caution.
  • Hepatic impairment
    • In the case of advanced liver disease, use caution.
  • Renal impairment
    • Patients with a GFR of less than 50 ml/min should be cautious and adjusted accordingly.

Cetirizine (systemic): Drug Interaction

Risk Factor C (Monitor therapy)

Acetylcholinesterase Inhibitors

May diminish the therapeutic effect of Anticholinergic Agents. Anticholinergic Agents may diminish the therapeutic effect of Acetylcholinesterase Inhibitors.

Alcohol (Ethyl)

Alcohol's CNS depressing impact may be amplified by CNS depressants (Ethyl).

Alizapride

May enhance the CNS depressant effect of CNS Depressants.

Amantadine

CNS depressants may have an enhanced CNS depressant impact.

Amezinium

Antihistamines may intensify Amezinium's stimulant effects.

Amphetamines

may lessen antihistamines' sedative effects.

Anticholinergic Agents

Other anticholinergic agents' negative or hazardous effects could be amplified.

Betahistine

Betahistine's therapeutic impact may be reduced by antihistamines.

Botulinum Toxin-Containing Products

may strengthen an anticholinergic agent's anticholinergic action.

Brexanolone

Brexanolone's CNS depressing effects may be amplified by other CNS depressants.

Brimonidine (Topical)

May enhance the CNS depressant effect of CNS Depressants.

Bromopride

May enhance the CNS depressant effect of CNS Depressants.

Cannabidiol

May enhance the CNS depressant effect of CNS Depressants.

Cannabis

May enhance the CNS depressant effect of CNS Depressants.

Chloral Betaine

May enhance the adverse/toxic effect of Anticholinergic Agents.

Chlorphenesin Carbamate

May enhance the adverse/toxic effect of CNS Depressants.

CNS Depressants

May enhance the adverse/toxic effect of other CNS Depressants.

Dimethindene (Topical)

May enhance the CNS depressant effect of CNS Depressants.

Doxylamine

May enhance the CNS depressant effect of CNS Depressants. Management: The manufacturer of Diclegis (doxylamine/pyridoxine), intended for use in pregnancy, specifically states that use with other CNS depressants is not recommended.

Dronabinol

May enhance the CNS depressant effect of CNS Depressants.

Erdafitinib

May increase the serum concentration of P-glycoprotein/ABCB1 Substrates.

Esketamine

May enhance the CNS depressant effect of CNS Depressants.

Gastrointestinal Agents (Prokinetic)

Anticholinergic Agents may diminish the therapeutic effect of Gastrointestinal Agents (Prokinetic).

Glucagon

Anticholinergic Agents may enhance the adverse/toxic effect of Glucagon. Specifically, the risk of gastrointestinal adverse effects may be increased.

HydrOXYzine

May enhance the CNS depressant effect of CNS Depressants.

Itopride

Anticholinergic Agents may diminish the therapeutic effect of Itopride.

Kava Kava

May enhance the adverse/toxic effect of CNS Depressants.

Lofexidine

May enhance the CNS depressant effect of CNS Depressants. Management: Drugs listed as exceptions to this monograph are discussed in further detail in separate drug interaction monographs.

Lumacaftor

May decrease the serum concentration of P-glycoprotein/ABCB1 Substrates. Lumacaftor may increase the serum concentration of P-glycoprotein/ABCB1 Substrates.

Magnesium Sulfate

May enhance the CNS depressant effect of CNS Depressants.

MetyroSINE

CNS Depressants may enhance the sedative effect of MetyroSINE.

Mianserin

May enhance the anticholinergic effect of Anticholinergic Agents.

Minocycline

May enhance the CNS depressant effect of CNS Depressants.

Mirabegron

Anticholinergic Agents may enhance the adverse/toxic effect of Mirabegron.

Mirtazapine

CNS Depressants may enhance the CNS depressant effect of Mirtazapine.

Nabilone

May enhance the CNS depressant effect of CNS Depressants.

Nitroglycerin

Anticholinergic Agents may decrease the absorption of Nitroglycerin. Specifically, anticholinergic agents may decrease the dissolution of sublingual nitroglycerin tablets, possibly impairing or slowing nitroglycerin absorption.

P-glycoprotein/ABCB1 Inducers

May decrease the serum concentration of Pglycoprotein/ABCB1 Substrates. P-glycoprotein inducers may also further limit the distribution ofp-glycoprotein substrates to specific cells/tissues/organs where p-glycoprotein is present in large amounts (e.g., brain, T-lymphocytes, testes, etc.).

P-glycoprotein/ABCB1 Inhibitors

May increase the serum concentration of Pglycoprotein/ABCB1 Substrates. P-glycoprotein inhibitors may also enhance the distribution of pglycoprotein substrates to specific cells/tissues/organs where p-glycoprotein is present in large amounts (e.g., brain, T-lymphocytes, testes, etc.).

Pilsicainide

May increase the serum concentration of Cetirizine (Systemic). Cetirizine (Systemic) may increase the serum concentration of Pilsicainide.

Piribedil

CNS Depressants may enhance the CNS depressant effect of Piribedil.

Pitolisant

Antihistamines may diminish the therapeutic effect of Pitolisant.

Pramipexole

CNS Depressants may enhance the sedative effect of Pramipexole.

Ramosetron

Anticholinergic Agents may enhance the constipating effect of Ramosetron.

Ranolazine

May increase the serum concentration of P-glycoprotein/ABCB1 Substrates.

ROPINIRole

CNS Depressants may enhance the sedative effect of ROPINIRole.

Rotigotine

CNS Depressants may enhance the sedative effect of Rotigotine.

Rufinamide

May enhance the adverse/toxic effect of CNS Depressants. Specifically, sleepiness and dizziness may be enhanced.

Selective Serotonin Reuptake Inhibitors

CNS Depressants may enhance the adverse/toxic effect of Selective Serotonin Reuptake Inhibitors. Specifically, the risk of psychomotor impairment may be enhanced.

Tetrahydrocannabinol

May enhance the CNS depressant effect of CNS Depressants.

Tetrahydrocannabinol and Cannabidiol

May enhance the CNS depressant effect of CNS Depressants.

Thiazide and Thiazide-Like Diuretics

Anticholinergic Agents may increase the serum concentration of Thiazide and Thiazide-Like Diuretics.

Topiramate

Anticholinergic Agents may enhance the adverse/toxic effect of Topiramate.

Trimeprazine

May enhance the CNS depressant effect of CNS Depressants.

Risk Factor D (Consider therapy modification)

Benzylpenicilloyl Polylysine

Antihistamines may diminish the diagnostic effect of Benzylpenicilloyl Polylysine. Management: Suspend systemic H1 antagonists for benzylpenicilloyl-polylysine skin testing and delay testing until systemic antihistaminic effects have dissipated. A histamine skin test may be used to assess persistent antihistaminic effects.

Blonanserin

CNS Depressants may enhance the CNS depressant effect of Blonanserin.

Buprenorphine

CNS Depressants may enhance the CNS depressant effect of Buprenorphine. Management: Consider reduced doses of other CNS depressants, and avoiding such drugs in patients at high risk of buprenorphine overuse/self-injection. Initiate buprenorphine patches (Butrans brand) at 5 mcg/hr in adults when used with other CNS depressants.

Chlormethiazole

May enhance the CNS depressant effect of CNS Depressants. Management: Monitor closely for evidence of excessive CNS depression. The chlormethiazole labeling states that an appropriately reduced dose should be used if such a combination must be used.

Droperidol

May enhance the CNS depressant effect of CNS Depressants. Management: Consider dose reductions of droperidol or of other CNS agents (eg, opioids, barbiturates) with concomitant use. Exceptions to this monograph are discussed in further detail in separate drug interaction monographs.

Flunitrazepam

CNS Depressants may enhance the CNS depressant effect of Flunitrazepam.

Hyaluronidase

Antihistamines may diminish the therapeutic effect of Hyaluronidase. Management: Patients receiving antihistamines (particularly at larger doses) may not experience the desired clinical response to standard doses of hyaluronidase. Larger doses of hyaluronidase may be required.

HYDROcodone

CNS Depressants may enhance the CNS depressant effect of HYDROcodone. Management: Avoid concomitant use of hydrocodone and benzodiazepines or other CNS depressants when possible. These agents should only be combined if alternative treatment options are inadequate. If combined, limit the dosages and duration of each drug.

Methotrimeprazine

CNS Depressants may enhance the CNS depressant effect of Methotrimeprazine. Methotrimeprazine may enhance the CNS depressant effect of CNS Depressants. Management: Reduce adult dose of CNS depressant agents by 50% with initiation of concomitant methotrimeprazine therapy. Further CNS depressant dosage adjustments should be initiated only after clinically effective methotrimeprazine dose is established.

Opioid Agonists

CNS Depressants may enhance the CNS depressant effect of Opioid Agonists. Management: Avoid concomitant use of opioid agonists and benzodiazepines or other CNS depressants when possible. These agents should only be combined if alternative treatment options are inadequate. If combined, limit the dosages and duration of each drug.

OxyCODONE

CNS Depressants may enhance the CNS depressant effect of OxyCODONE. Management: Avoid concomitant use of oxycodone and benzodiazepines or other CNS depressants when possible. These agents should only be combined if alternative treatment options are inadequate. If combined, limit the dosages and duration of each drug.

Perampanel

May enhance the CNS depressant effect of CNS Depressants. Management: Patients taking perampanel with any other drug that has CNS depressant activities should avoid complex and high-risk activities, particularly those such as driving that require alertness and coordination, until they have experience using the combination.

Pramlintide

May enhance the anticholinergic effect of Anticholinergic Agents. These effects are specific to the GI tract.

Secretin

Anticholinergic Agents may diminish the therapeutic effect of Secretin. Management: Avoid concomitant use of anticholinergic agents and secretin. Discontinue anticholinergic agents at least 5 half-lives prior to administration of secretin.

Sodium Oxybate

May enhance the CNS depressant effect of CNS Depressants. Management: Consider alternatives to combined use. When combined use is needed, consider minimizing doses of one or more drugs. Use of sodium oxybate with alcohol or sedative hypnotics is contraindicated.

Suvorexant

CNS Depressants may enhance the CNS depressant effect of Suvorexant. Management: Dose reduction of suvorexant and/or any other CNS depressant may be necessary. Use of suvorexant with alcohol is not recommended, and the use of suvorexant with any other drug to treat insomnia is not recommended.

Tapentadol

May enhance the CNS depressant effect of CNS Depressants. Management: Avoid concomitant use of tapentadol and benzodiazepines or other CNS depressants when possible. These agents should only be combined if alternative treatment options are inadequate. If combined, limit the dosages and duration of each drug.

Zolpidem

CNS Depressants may enhance the CNS depressant effect of Zolpidem. Management: Reduce the Intermezzo brand sublingual zolpidem adult dose to 1.75 mg for men who are also receiving other CNS depressants. No such dose change is recommended for women. Avoid use with other CNS depressants at bedtime; avoid use with alcohol.

Risk Factor X (Avoid combination)

Aclidinium

May enhance the anticholinergic effect of Anticholinergic Agents.

Azelastine (Nasal

CNS Depressants may enhance the CNS depressant effect of Azelastine (Nasal).

Bromperidol

May enhance the CNS depressant effect of CNS Depressants.

Cimetropium

Anticholinergic Agents may enhance the anticholinergic effect of Cimetropium.

Eluxadoline

Anticholinergic Agents may enhance the constipating effect of Eluxadoline.

Glycopyrrolate (Oral Inhalation

Anticholinergic Agents may enhance the anticholinergic effect of Glycopyrrolate (Oral Inhalation).

Glycopyrronium (Topical)

May enhance the anticholinergic effect of Anticholinergic Agents.

Ipratropium (Oral Inhalation)

May enhance the anticholinergic effect of Anticholinergic Agents.

Levosulpiride

Anticholinergic Agents may diminish the therapeutic effect of Levosulpiride.

Orphenadrine

CNS Depressants may enhance the CNS depressant effect of Orphenadrine.

Oxatomide

May enhance the anticholinergic effect of Anticholinergic Agents.

Oxomemazine

May enhance the CNS depressant effect of CNS Depressants.

Paraldehyde

CNS Depressants may enhance the CNS depressant effect of Paraldehyde.

Potassium Chloride

Anticholinergic Agents may enhance the ulcerogenic effect of Potassium Chloride. Management: Patients on drugs with substantial anticholinergic effects should avoid using any solid oral dosage form of potassium chloride.

Potassium Citrate

Anticholinergic Agents may enhance the ulcerogenic effect of Potassium Citrate.

Revefenacin

Anticholinergic Agents may enhance the anticholinergic effect of Revefenacin.

Thalidomide

CNS Depressants may enhance the CNS depressant effect of Thalidomide.

Tiotropium

Anticholinergic Agents may enhance the anticholinergic effect of Tiotropium.

Umeclidinium

May enhance the anticholinergic effect of Anticholinergic Agents.

Monitoring parameters:

Monitor the patient's response to therapy, mental status, and anticholinergic effects 

How to take Cetirizine?

It is administered without regard to meals. The Chewable tablet should be chewed before swallowing 

Mechanism of action of Cetirizine:

Cetirizine is a competitor to histamine receptors found in the gastrointestinal tract and blood vessels as well as the respiratory tract.

The treatment of allergies by inhibiting histamine can result in relief (by using vasoconstrictive properties, and inhibition of the chemotaxis between basophils and eosinophils).

The Onset of Action is about 0.7 hours, and cutaneous allergic symptoms can be suppressed for about 24 hours.

It is rapidly absorbed and is 93% bound with proteins.

 The half-life elimination of Cetirizine in children is 6.2 hours, and in adults is 8 hours.

It takes one hour to reach peak serum concentration. 

It is excreted mostly via urine, as an unchanged drug.

Cetirizine brand names:

  • All Day Allergy Children's
  • All Day Allergy
  • Allergy Relief
  • Allergy
  • Relief/Indoor/Outdoor
  • Cetirizine HCl Allergy Child
  • Cetirizine HCl Children's Allergy
  • Cetirizine HCl Hives Relief
  • GoodSense All Day Allergy
  • Zyrtec Allergy
  • Zyrtec Children's Allergy
  • Aceterin
  • Aceto
  • Acidrine
  • Acitrin
  • Acura
  • Adezio
  • Agelmin
  • Alatro
  • Alercet
  • Alercina
  • Alergine
  • Alerid
  • Alerid-10
  • Allercet
  • Allergy-Care
  • Allerkid
  • Allersan
  • Allertek
  • Alyr
  • Alzyr
  • Alzytec
  • Amertil
  • Anti-Hist Allergy
  • Aricetin
  • Arix
  • Artiz
  • Ascet
  • Askey
  • Askey DT
  • Atopix
  • Atrizin
  • Bluetec
  • Cabal
  • Ceritec
  • Cetallerg
  • Cetigen
  • Cetihexal
  • Cetihis
  • Cetimed
  • Cetiram
  • Cetirax
  • CetirHexal
  • Cetirin
  • Cetiristad
  • Cetix
  • Cetixin
  • Cetizin
  • Cetrak
  • Cetrimed
  • Cetrine
  • Cetrix
  • Cetro
  • Cetymin
  • Cezera
  • Cezin
  • Epirizine
  • Estin
  • Falergi
  • Finallerg
  • Gencet
  • Glotrizine
  • Green Nose
  • H-One
  • Histacet
  • Histacetin
  • Histalong
  • Histazine
  • Histec
  • Lergium
  • Letizen
  • N-Alergya
  • Nohist
  • Noler
  • Nosemin
  • Omcet
  • Ozen
  • Parlazin
  • Prixlae
  • Razene
  • Reactin
  • Reactine
  • Rolinoz
  • Ronex
  • Ryvel
  • Ryzen
  • Ryzicor
  • Selitex
  • Simtec
  • Sunizine
  • Sutac
  • Talzic
  • Terizin
  • Texzine
  • Tirizine
  • Triz
  • Trizin 5
  • Virlix
  • Xero-Sed
  • Zensil
  • Zericin
  • Zertin
  • Zertine
  • Zetaler
  • Zetalerg
  • Zetop
  • Zilarex
  • Zirec
  • Zirpine
  • Zirtec
  • Zirtek
  • Zirtin
  • Zodac
  • Zyllergy
  • Zyncet
  • Zyrac
  • Zyrak
  • Zyrcon
  • Zyrfar
  • Zyrlex
  • Zyrrtec
  • Zyrtec
  • Zyrtec Allergy
  • Zyrtec-R

Cetirizine Brands in Pakistan:

Cetirizine [Syrup 1 Mg/Ml]

Neset

Surge Laboratories (Pvt) Ltd

 

Cetirizine [Syrup 1 Mg/5ml]

Baydal

Bayer Health Care

 

Cetirizine [Syrup 2 Mg/5ml]

CLOMIN

GLITZ PHARMA

 

Cetirizine [Syrup 5 Mg/5ml]

AKSOZINE

AKSON PHARMACEUTICALS (PVT) LTD.

ALCE

DERMA TECHNO PAKISTAN

ALERID

PHARMATEC PAKISTAN (PVT) LTD.

ALGEZEN

OLIVE LABORATORIES

ALLAMINE

SHAFAZ PHARMA INTERNATIONAL (PVT) LTD.

ALLOS

ADAMJEE PHARMACEUTICALS (PVT) LTD.

ALZINE

BIOGENICS PAKISTAN (PVT) LTD.

ARIX

TABROS PHARMA

ASKOGIX

IDEAL PHARMACEUTICAL INDUSTRIES

AVEC

PLATINUM PHARMACEUTICALS (PVT.) LTD.

CENEX

DR. RAZA PHARMA (PRIVATE) LIMITED

CERIGEX

FEDRO PHARMACEUTICAL

CERIZINE

PHARMEVO (PVT) LTD.

CETRIN

PARAMOUNT PHARMACEUTICALS

CETRIZA

SAYYED PHARMACEUTICALS

CETSUN

HISUN PHARMACEUTICALS

CETZI

JAWA PHARMACEUTICALS(PVT) LTD.

CEZINE

P.D.H. PHARMACEUTICALS (PVT) LTD.

CEZIX

PEARL PHARMACEUTICALS

CISTAZINE

PHARMEDIC (PVT) LTD.

CITPHARM

EPHARM LABORATORIES

CITRICARE

CARE PHARMACEUTICALS

CTZINE

MEDICRAFT PHARMACEUTICALS (PVT) LTD.

DAVIZIN

DAVIS PHARMACEUTICAL LABORATORIES

DAYLONG

TRIGON PHARMACEUTICALS PAKISTAN (PVT) LTD.

DEEBAR

MEDICEENA PHARMA (PVT) LTD.

DICET

SHROOQ PHARMACEUTICALS

DOPNIL

STANDPHARM PAKISTAN (PVT) LTD.

EIDEM

DELUX CHEMICAL INDUSTRIES

FASTIC

SEMOS PHARMACEUTICALS (PVT) LTD.

GIXER

BARRETT HODGSON PAKISTAN (PVT) LTD.

HISTEX

XENON PHARMACEUTICALS (PVT) LTD.

INCIDAL-NEO

BAYER HEALTH CARE

INZEE

INDUS PHARMA (PVT) LTD.

ITIZ

ZANCTOK PHARMACEUTICALS

LOTOZIN

LOTUS PHARMACEUTICALS (PVT) LTD

MACRIZINE

MAC & RANS PHARMACEUTICALS (PVT) LTD

MAXZINE

MAX PHARMACEUTICALS

MIRAZIN

MIRACLE PHARMACEUTICALS(PVT) LTD

NEOZINE

NEO MEDIX

NEUTRIZINE

NEUTRO PHARMA (PVT) LTD.

NIMZINE

NIMRALL LABORATORIES

NO ALL

HARMANN PHARMACEUTICAL LABORATORIES (PVT) LTD.

RAKZINE

RAKAPOSHI PHARMACEUTICAL (PVT) LTD.

REGOGEX

REGENT LABORATORIES LTD.

REX

ALBRO PHARMA

RHIZIN

CIBEX (PRIVATE) LIMITED

RONEX

HILTON PHARMA (PVT) LIMITED

ROZEN

RASCO PHARMA

SAPIZINE

SAPIENT PHARMA

SEDIL

SAMI PHARMACEUTICALS (PVT) LTD.

STAMIN

Shaigan Pharmaceuticals (PVT) LTD

STAND CITRI

STANDARD DRUG CO.

TICZINE

LOWITT PHARMACEUTICALS (PVT) LTD

TIRIX

ALLIANCE PHARMACEUTICALS (PVT) LTD.

ZANLAN

NOVARTIS PHARMA (PAK) LTD

ZANLAN

NOVARTIS PHARMA (PAK) LTD

ZECIT

POLYFINE CHEMPHARMA (PVT) LTD.

ZETRINE

EFROZE CHEMICAL INDUSTRIES (PVT) LTD.

ZILCIT

ZINTA PHARMACEUTICALS INDUSTRIES

ZINE

LIBRA PHARMACEUTICALS (PVT) LTD

ZYRET

REX PHARMACEUTICALS PAKISTAN

ZYRTEC

AGP (PRIVATE) LTD.

 

Cetirizine [Susp 1 Mg/5ml]

CETRANEN

NENZA PHARMACEUTICALS (PVT) LIMITED

 

Cetirizine [Susp 5 Mg/5ml]

CETRAZIT

ATLANTIC PHARMACEUTICALS (PVT) LTD.

 

Cetirizine [Soln 5 Mg/5ml]

LINAZINE

ALINA COMBINE PHARMACEUTICALS (PVT) LTD.

 

Cetirizine [Oral Soln 5 Mg/5ml]

RIGIX

AGP (PRIVATE) LTD.

 

Cetirizine [Tabs 10 Mg]

ACTILIX-CTZ

GLAXOSMITHKLINE

AKSOZINE

AKSON PHARMACEUTICALS (PVT) LTD.

ALARZA

MAX PHARMACEUTICALS

ALARZA

MAX PHARMACEUTICALS

ALCE

DERMA TECHNO PAKISTAN

ALCIT

HIZAT PHARMACEUTICAL INDUSTRIES (PVT) LTD.

ALEGRA

TAGMA PHARMA (PVT) LTD.

ALER

LLOYDS PHARMACEUTICALS

ALERGO

PHARMIX LABORATORIES (PRIVATE) LIMITED.

ALERID

PHARMATEC PAKISTAN (PVT) LTD.

ALERWISE

PHARMAWISE LABS. (PVT) LTD.

ALERYAN

RORYAN PHARMACEUTICAL INDUSTRIES (PVT) LTD

ALERZINE

MEDERA PHARMACEUTICALS (PVT) LTD.

ALEX

INNVOTEK PHARMACEUTICALS

ALGEZEN

OLIVE LABORATORIES

ALLAMINE

SHAFAZ PHARMA INTERNATIONAL (PVT) LTD.

ALLERGID

HYGEIA PHARMACEUTICALS

ALLOS

ADAMJEE PHARMACEUTICALS (PVT) LTD.

ALZEX

ALSON PHARMACEUTICALS

ALZINE

BIOGENICS PAKISTAN (PVT) LTD.

AREX

DANAS PHARMACEUTICALS (PVT) LTD

ARIX

TABROS PHARMA

ASAZINE

ZEPHYR PHARMATEC (PVT) LTD.

ASKOGIX

IDEAL PHARMACEUTICAL INDUSTRIES

ASTEMINE

SIZA INTERNATIONAL (PVT) LTD.

AVAZIN

ASKARI PHARMACEUTICALS.

AVEC

PLATINUM PHARMACEUTICALS (PVT.) LTD.

BAYDAL

BAYER HEALTH CARE

BAYDAL

BAYER HEALTH CARE

BIOCIT

BIOGEN PHARMA

BYTEC

BATALA PHARMACEUTICALS.

CAYZINE

CAYLEX PHARMACEUTICALS (PVT) LTD.

CENE

VEGA PHARMACEUTICALS LTD.

CENEX

DR. RAZA PHARMA (PRIVATE) LIMITED

CERIDAL

AXIS PHARMACEUTICALS

CERIGEX

FEDRO PHARMACEUTICAL

CERIZINE

PHARMEVO (PVT) LTD.

CET

WILSHIRE LABORATORIES (PVT) LTD.

CETAHIST

PHARMACARE LABORATORIES (PVT) LTD.

CETIRIZINE

PULSE PHARMACEUTICALS

CETRANEN

NENZA PHARMACEUTICALS (PVT) LIMITED

CETRIAIM

AIMS TRADERS

CETRIHIT

UNIPHARMA (PVT) LTD.

CETRIMAK

MAKSON PHARMACEUTICALS

CETRIN

PARAMOUNT PHARMACEUTICALS

CETRIX

DON VALLEY PHARMACEUTICALS (PVT) LTD.

CETSUN

HISUN PHARMACEUTICALS

CETZI

JAWA PHARMACEUTICALS(PVT) LTD.

CEZEN

ENGLISH PHARMACEUTICALS INDUSTRIES

CEZINE

P.D.H. PHARMACEUTICALS (PVT) LTD.

CEZIX

PEARL PHARMACEUTICALS

CIPZIN

LEAMA CHEMI PHARMA (PVT.) LTD.

CISTAZINE

PHARMEDIC (PVT) LTD.

CITGEN

GENOME PHARMACEUTICALS (PVT) LTD

CITPHARM

EPHARM LABORATORIES

CITRESAL

UNIVERSAL PHARMACEUTICALS (PVT) LTD

CITRISAF

SAAAF PHARMACEUTICALS

CITRIWEL

WELMARK PHARMACEUTICALS

CITRIZA

SAYYED PHARMACEUTICALS

CITZAR

RORYAN PHARMACEUTICAL INDUSTRIES (PVT) LTD

CONCIDOL

CONVELL LABORATORIES

COXYZIN

GLOBAL PHARMACEUTICALS

CTZINE

MEDICRAFT PHARMACEUTICALS (PVT) LTD.

CYTEN

BLOOM PHARMACEUTICALS (PVT) LTD.

D-HISTINE

FLOW PHARMACEUTICALS (PVT) LTD.

DAISY

MEGA PHARMACEUTICALS (PVT) LTD

DAVIZIN

DAVIS PHARMACEUTICAL LABORATORIES

DEEBAR

MEDICEENA PHARMA (PVT) LTD.

DEMAST

PAKHEIM INTERNANATIONAL PHARMA

DICET

SHROOQ PHARMACEUTICALS

DOPNIL

STANDPHARM PAKISTAN (PVT) LTD.

EIDEM

DELUX CHEMICAL INDUSTRIES

FASTIC

SEMOS PHARMACEUTICALS (PVT) LTD.

FIRAX

USAWA PHARMACEUTICALS

FOZIN

FOZAN PHARMACEUTICALS INDUSTRIERS (PVT) LTD

GIXER

BARRETT HODGSON PAKISTAN (PVT) LTD.

GRAYZINE

GRAY`S PHARMACEUTICALS

HEALAZIN

HEAL PHARMACEUTICALS PVT LTD

HETRIZINE

SHAWAN PHARMACEUTICALS

HIRAZINE

21ST CENTURY PHARMACEUTICALS CO.

HISMATEC

Z-JANS PHARMACEUTICAL (PVT) LTD.

HISMIN

TRISON RESEARCH LABORATORIES (PVT) LTD

HISTANT

F.M. PHARMACEUTICALS INTERNATIONAL

HISTEX

XENON PHARMACEUTICALS (PVT) LTD.

INCIDAL-NEO

BAYER HEALTH CARE

INCIDAL-NEO

BAYER HEALTH CARE

INSTAZIN

FRIENDS PHARMA (PVT) LTD

INZEE

INDUS PHARMA (PVT) LTD.

ITRAT

SAYDON PHARMACEUTICAL INDUSTRIES (PVT) LTD.

LINAZINE

ALINA COMBINE PHARMACEUTICALS (PVT) LTD.

LOTOZIN

LOTUS PHARMACEUTICALS (PVT) LTD

LZINE

LINEAR PHARMA

MEDI-H1

MEDICON PHARMACEUTICALS INDUSTRIES (PVT) LTD

MISIDOL

HEALERS LABORATORIES

MUSTEX

MASS PHARMA (PRIVATE) LIMITED

NAWAZIN

NAWAN LABORATORIES (PVT) LTD.

NIMIZINE

NIMRALL LABORATORIES

NIMZINE

NIMRALL LABORATORIES

NIZEN

ZEPHYR PHARMATEC (PVT) LTD.

NO ALL

HARMANN PHARMACEUTICAL LABORATORIES (PVT) LTD.

NOSTAMIN

SANTE (PVT) LIMITED

NT HIST

ZESION PHARMACEUTICAL (PVT) LTD

OPTIZIN

CANDID PHARMACEUTICALS

ORTIZIN

OBSONS PHARMACEUTICALS

PANAZIN

PANACEA PHARMACEUTICALS

RAKZINE

RAKAPOSHI PHARMACEUTICAL (PVT) LTD.

REGOGEX

REGENT LABORATORIES LTD.

REX

ALBRO PHARMA

RHIZIN

CIBEX (PRIVATE) LIMITED

RIGIX

AGP (PRIVATE) LTD.

RONEX

HILTON PHARMA (PVT) LIMITED

ROTRAZIN

ROGEN PHARMACEUTICALS

ROZEN

RASCO PHARMA

SAPIZINE

SAPIENT PHARMA

SEDIL

SAMI PHARMACEUTICALS (PVT) LTD.

SELZINE

SELMORE AGENCIES

SERZINE

QINTAR PHARMACUTICALS

STAMIN

Shaigan Pharmaceuticals (PVT) LTD

STAND CITRI

STANDARD DRUG CO.

TICKNIL

SILVER OAK CORPORATION.

TICZINE

LOWITT PHARMACEUTICALS (PVT) LTD

TIRIX

ALLIANCE PHARMACEUTICALS (PVT) LTD.

TRINE

SHAHEEN AGENCIES

TRIZIM

REX PHARMACEUTICALS PAKISTAN

TRYZIN

PULSE PHARMACEUTICALS

TYZITEC

STAR LABORATORIES (PVT) LTD.

URTICAR

MEDERA PHARMACEUTICALS (PVT) LTD.

VIRLOS

FERROZA INTERNATIONAL PHARMACEUTICALS (PVT) LTD.

WEBZINE

WEBROS PHARMACEUTICALS

WINZIM

WNS FIELD PHARMACEUTICALS

XERO-SED

HAMAZ PHARMACEUTICAL (PVT) LTD.

XYDEN

DYSON RESEARCH LABORATORIES

Z-TEK

PAKHEIM INTERNANATIONAL PHARMA

ZANLAN

NOVARTIS PHARMA (PAK) LTD

ZANLAN

NOVARTIS PHARMA (PAK) LTD

ZEATIN

GLAXOSMITHKLINE

ZEC

MEDISURE LABORATORIES PAKISTAN (PVT.) LTD.

ZECIT

POLYFINE CHEMPHARMA (PVT) LTD.

ZETRINE

EFROZE CHEMICAL INDUSTRIES (PVT) LTD.

ZILCIT

ZINTA PHARMACEUTICALS INDUSTRIES

ZINE

LIBRA PHARMACEUTICALS (PVT) LTD

ZINGO

GOODMAN INTERNATIONAL,

ZINOLUR

REMINGTON PHARMACEUTICAL INDUSTRIES (PVT) LTD.

ZIRTEK

HANSEL PHARMACEUTICALS PVT (LTD)

ZYRTEC

AGP (PRIVATE) LTD.

ZYSIC

JINNAH PHARMACEUTICALS

ZYTIZINE

SHAZALS PHARMACEUTICALS

 

Cetirizine [Caps 10 Mg]

CETORID

HOOVER PHARMACEUTICALS (PVT) LTD

TARCIT

SEARLE PAKISTAN (PVT.) LTD.