Biotin or vitamin H is used as over the counter dietary supplement. It is commonly used as a dietary supplement for hair growth, brittle nails, neuronal function, conjunctivitis, and dermatitis. Deficiency of biotin may result in developmental delay, hypotonia, seizures, alopecia, dermatitis, coma, hyperammonemia, rash, and ketoacidosis. Order Biotin 

Biotin (Vitamin H) Dose in Adults

Biotin as a dietary supplementation (OTC labeling):

• • One tablet or capsule daily

Biotin (Vitamin H) Dose in Childrens

Use as Adequate intake:

• Infants:
  • 1 - 6 months:
    • 5 mcg/day
  • 7 - 12 months:
    • 6 mcg/day
• Children and Adolescents:
  • 1 - 3 years:
    • 8 mcg/day
  • 4 - 8 years:
    • 12 mcg/day
  • 9 - 13 years:
    • 20 mcg/day
  • 14 - 18 years:
    • 25 mcg/day

Use in the treatment of symptomatic Biotinidase deficiency:

• Infants, Children, and Adolescents:
  • 5 - 20 mg orally once a day.

Pregnancy Risk Factor: B

• It is a water soluble vitamin and crosses the placental barrier.

Vitamin H use during breastfeeding:

• It is excreted in breastmilk and may be continued during lacatation.

Biotin (Vitamin H) Dose in Renal Disease:

• Adjustment in dose has not been recommended by the manufacturer in patients with kidney disease.

Biotin (Vitamin H) Dose in LIver Disease:

• Adjustment in dose has not been recommended by the manufacturer in patients with liver disease.

Side Effects of Biotin (Vitamin H)

Adverse effects have not been listed in the manufacturer's labeling.

Contraindication to Biotin (Vitamin H)

Warnings & Precautions

• Lab tests:
  • Patients taking high levels of biotin may have some laboratory errors.
  • Biotin technology can be used to test certain commonly ordered tests such as Troponin. It also allows for the testing of hormones using biotin to bind specific proteins.
  • If the pateints clinical symptms and the lab test result do not correspond, biotin interference should be considered as a possible source of error (FDA medicine watch - Biotin interfernece)

Monitoring Parameters:

None required.

How to take Biotin (Vitamin H)?

• It is administered orally without regard to meals (but may be preferable to take it with meals).

Mechanism of action of Biotin (Vitamin H):

It functions as a coenzyme, participates in the catabolism and metabolism of leucine, propionate metabolism, and the carboxylation, transcarboxylation,  and decarboxylation events for gluconeogenesis and lipogenesis (the production of fatty acids).

International brand names of Biotin (Vitamin H):

• Aminosam
• BIO-H-TIN
• Bioak
• Biotiforte
• Biotin A
• Biotin Forte
• Biotinol
• Curatin
• Deacura
• HAARNA mono Biotin
• Hiotin
• Medobiotin
• Untral

Biotin brands in Pakistan: