Can you differentiate between Myopathy and Neuroapthy based on your clinical examination findings?
Serum anti-tissue transglutaminase IgA (tTG-IgA) levels can reliably diagnose celiac disease without the need for a diagnostic bowel biopsy in adults without IgA deficiency. This approach has a hig...
New drugs are being tested for the treatment of Multiple Myeloma to find the least toxic and most potent one. Let's talk about how these drugs act.
NOACs (novel oral anticoagulants) or DOACs (direct oral anticoagulants) are considered safe alternatives to VKAs ( vitamin k antagonists) like warfarin. However, in a recent trial conducted in Frai...
"Night owls" are people who sleep late and wake up late while early birds are the opposite. In a recent study published in the Annals of internal medicine, it was found that "night o...
What are the most important investigations to order in this young girl with a palpable purpura? When would you recommend corticosteroids?
This young gentleman presented with a history of depression and visual impairment. Here is his picture: What investigations will you order to reach a diagnosis?
SOHONOS (palovarotene) is a retinoid approved for the treatment of a very rare disease, Stone man Disease. Stone man disease is called fibrodysplasia ossificans progressiva (FOP). How do pa...
List a few causes of Functional Asplenia (Hyposplenism). How can we check for functional asplenia?
How can we differentiate between murmurs of mitral regurgitation and VSD?
What is a functional murmur? How can you differentiate between an organic murmur and a functional murmur?
What are the clinical signs of Mitral Regurgitation? Apex beat: S1: Murmur: Other features:
What are the clinical signs of Mitral Stenosis? Apex beat: S1: Murmur: Other features:
Two drugs have shown incredible weight loss and A1C reduction in phase 2 Trials. These are: Retatrutide CagriSema Retatrutide is a TriG agonist (GLP-1, GIP, and Glucagon). CagriSema is a...
What is an Austin Flint murmur?
Two cases of monkeypox have been reported in Pakistan. It manifests as: A rash similar to smallpox Fever, and Lymphadenopathy The diagnosis is made via PCR testing of fluid taken fro...
Adcetris is the brand name of Brentuximab Vedotin. This drug is unique as it has two different components: Brentuximab and Vedotin Brentuximab is a monoclonal antibody that carries...
Sparsentan is a newly approved drug by the FDA for the treatment of high-risk patients with IgA Nephropathy. It has a unique mechanism of action as it blocks two receptors simultaneously: Endoth...