Trelagliptin is a once weekly DPP-IV inhibitor. It has been approved in Japan in 2015 for the treatment of Diabetes Type 2. Trelagliptin has not been submitted for approval by the FDA and EMA for u...
Tetrabenazine is Vesicular monoaminetransporter type 2 i(VMAT-2) inhibitor. It inhibits excitatory stimuli in the brain. It is used to treat hyperactive disorders such as Huntington's chorea....
List the causes of jaundice: Hepatic Causes Pre-hepatic Causes Post-hepatic Causes
What is clubbing and how do we grade it? What are the causes of clubbing?
According to the CDC, individuals with the following risk factors are at an increased risk of getting severe flu and flu-related complications such as pneumonia and respiratory failure: Asthma...
Daratumumab + Lenalidomide + Dexamethasone is better than Bortezomib + Lenalidomide + Dexamethasone [Ref]
TRUQAP, along with fulvestrant, is used to treat adults with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, locally advanced, or metastatic breast cancer....
Iptacopan helps control the alternative complement pathway by binding to Factor B. This regulation includes managing the cleavage of C3, influencing downstream effects, and controlling the amplific...
Diet, exercise, weight loss medicines, and surgery. Its not always like that. Sometimes, you have to jump straight to surgery. In a recent post published in Medscape, a senior, triple board certifi...
List the causes of Splitting and Reversed Splitting of the second heart sound.
In two randomized, double-blind, placebo-controlled clinical trials, the safety and effectiveness of OMVOH were assessed. The first study (UC-1, NCT03518086) focused on inducing remission, while th...
Reason of recurrent abdominal pain in porphyria??
The diagnosis and treatment of DKA have been changed because of the increasing number of cases of euglycemic DKA. What is the cut-off blood glucose to diagnose DKA?
We have a patient admitted in private ward. He was admitted initially by the Neurology department for evaluation of right sided headache and red eyes. MR was done for suspicion of cavernous sinus t...
Can you differentiate between Myopathy and Neuroapthy based on your clinical examination findings?
Serum anti-tissue transglutaminase IgA (tTG-IgA) levels can reliably diagnose celiac disease without the need for a diagnostic bowel biopsy in adults without IgA deficiency. This approach has a hig...
New drugs are being tested for the treatment of Multiple Myeloma to find the least toxic and most potent one. Let's talk about how these drugs act.
NOACs (novel oral anticoagulants) or DOACs (direct oral anticoagulants) are considered safe alternatives to VKAs ( vitamin k antagonists) like warfarin. However, in a recent trial conducted in Frai...
"Night owls" are people who sleep late and wake up late while early birds are the opposite. In a recent study published in the Annals of internal medicine, it was found that "night o...