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Biopsy Not Needed for Diagnosing Celiac Disease!
Author: Dr. Ahmed Farhan, 8 months ago

Serum anti-tissue transglutaminase IgA (tTG-IgA) levels can reliably diagnose celiac disease without the need for a diagnostic bowel biopsy in adults without IgA deficiency. This approach has a hig...


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Targeting Myeloma Cells
Author: Dr. Ahmed Farhan, 8 months ago

New drugs are being tested for the treatment of Multiple Myeloma to find the least toxic and most potent one. Let's talk about how these drugs act.


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NOACs or Warfarin in Frail patients with atrial fibrillation
Author: Dr. Ahmed Farhan, 8 months ago

NOACs (novel oral anticoagulants) or DOACs (direct oral anticoagulants) are considered safe alternatives to VKAs ( vitamin k antagonists) like warfarin. However, in a recent trial conducted in Frai...


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Are you a "Night Owl" or an "Early Bird"?
Author: Dr. Ahmed Farhan, 8 months ago

"Night owls" are people who sleep late and wake up late while early birds are the opposite. In a recent study published in the Annals of internal medicine, it was found that "night o...


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Henoch-Schonlein Purpura (HSP): IgA Vasculitis
Author: owner, 8 months ago

What are the most important investigations to order in this young girl with a palpable purpura? When would you recommend corticosteroids?


1 Replies
What important clinical finding is present in this patients eyes?
Author: owner, 8 months ago

This young gentleman presented with a history of depression and visual impairment. Here is his picture: What investigations will you order to reach a diagnosis?


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SOHONOS (palovarotene)
Author: Dr. Ahmed Farhan, 9 months ago

SOHONOS (palovarotene) is a retinoid approved for the treatment of a very rare disease, Stone man Disease. Stone man disease is called fibrodysplasia ossificans progressiva (FOP). How do pa...


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Functional Asplenia
Author: owner, 9 months ago

List a few causes of Functional Asplenia (Hyposplenism). How can we check for functional asplenia?


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Splenomegaly
Author: owner, 2 years ago

What are the causes of massive splenomegaly?


4 Replies
Mitral Regurgitation Vs VSD
Author: Dr. Ahmed Farhan, 9 months ago

How can we differentiate between murmurs of mitral regurgitation and VSD?


1 Replies
Functional Murmur
Author: owner, 10 months ago

What is a functional murmur? How can you differentiate between an organic murmur and a functional murmur?


2 Replies
Mitral Regurgitation
Author: owner, 1 year ago

What are the clinical signs of Mitral Regurgitation? Apex beat: S1: Murmur: Other features:


4 Replies
Mitral Stenosis
Author: owner, 1 year ago

What are the clinical signs of Mitral Stenosis? Apex beat: S1: Murmur: Other features:


3 Replies
Causes of a 'Loud S1'
Author: owner, 10 months ago

What are the causes of a 'Loud S1'?


5 Replies
New Weight Loss Drugs
Author: owner, 10 months ago

Two drugs have shown incredible weight loss and A1C reduction in phase 2 Trials. These are: Retatrutide CagriSema Retatrutide is a TriG agonist (GLP-1, GIP, and Glucagon). CagriSema is a...


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Austin flint murmur
Author: owner, 1 year ago

What is an Austin Flint murmur?


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Monkeypox cases in Pakistan
Author: Dr. Ahmed Farhan, 1 year ago

Two cases of monkeypox have been reported in Pakistan. It manifests as: A rash similar to smallpox Fever, and Lymphadenopathy The diagnosis is made via PCR testing of fluid taken fro...


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Adcetris (Brentuximab Vedotin)
Author: Dr. Ahmed Farhan, 1 year ago

Adcetris is the brand name of Brentuximab Vedotin. This drug is unique as it has two different components:  Brentuximab and Vedotin Brentuximab is a monoclonal antibody that carries...


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Sparsentan
Author: owner, 1 year ago

Sparsentan is a newly approved drug by the FDA for the treatment of high-risk patients with IgA Nephropathy. It has a unique mechanism of action as it blocks two receptors simultaneously: Endoth...


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MAC (Mycobacterium Avium Complex)
Author: Dr. Ahmed Farhan, 1 year ago

How can we diagnose MAC infection?


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