Dyclonine is a local anesthetic that is primarily used topically to relieve pain and itching caused by conditions such as minor burns, insect bites, and skin irritations. It works by blocking nerve signals in the body.

Dyclonine is commonly found in over-the-counter products such as throat lozenges or sprays for sore throat relief, as well as in creams and ointments for skin conditions. It is generally considered safe when used as directed, but like any medication, it can cause side effects in some individuals, such as skin irritation or allergic reactions.

Dyclonine (Sucrets) is used as a topical anesthetic that is administered as oral lozenges or sprays prior to procedures such as endoscopy and laryngoscopy. It is also used for the symptomatic relief of oral and throat pain and cough in patients with pharyngitis and following inhalation of irritants or cold.

Dyclonine (Sucrets) Uses:

• Cough:
  • It is indicated for the temporary relief of cough caused by inhaled irritants and associated with a cold.
• Mouth and throat symptoms:
  • It is indicated for the temporary relief of oral and throat symptoms such as sore throat, pai, or irritation.

Dyclonine Adult dose:

Dyclonine (Sucrets) Dose in the treatment of Mouth and throat symptoms:

• Take one lozenge.
• Put it in your mouth.
• Let it dissolve slowly.
• You can use one lozenge every two hours if you need to.
• But don't use more than 10 lozenges in one day.

Dyclonine Dose in children:

Dyclonine (Sucrets) Dose in the treatment of Mouth and throat symptoms: 

For children aged 6 years and older, as well as adolescents:

• Take one 2 mg dyclonine lozenge.
• Put it in your mouth.
• Let it dissolve slowly.
• You can use one lozenge every two hours if needed.
• Don't use more than 10 lozenges in one day.

For children aged 4 years and older, as well as adolescents, using the 2 mg lozenge with menthol 5 mg and pectin 6 mg:

• Follow the same instructions as above.

For children aged 4 years and older, as well as adolescents, using the 3 mg lozenge with menthol 6 mg:

• Follow the same instructions as above.

Always make sure to use the correct product for the age group specified and follow the recommended dosing instructions to ensure safety and effectiveness.

Use in Pregnancy and Lactation:

No dosage adjustments recommended. Since it is used as a topical anesthetic, it may be used safely during pregnancy and lactation. 

Dose in Kidney disease:

• The manufacturer's labeling for dyclonine does not include specific dosage adjustments for individuals with renal impairment.
• This means that there are no special instructions or changes in the recommended dosage for people with kidney problems.

Dose in Liver disease:

• According to the manufacturer's labeling, there are no specific dosage adjustments provided for dyclonine in individuals with hepatic (liver) impairment.
• This means that there are no special instructions or changes in the recommended dosage for people with liver problems.

Side effects of Dyclonine (Sucrets):

• Central Nervous System:
  • Feeling Hot
  • Localized Numbness
  • Localized Warm Feeling
  • Sensation Of Cold
• Gastrointestinal:
  • Burning Sensation Of Mouth
• Hypersensitivity:
  • Hypersensitivity Reaction
• Local:
  • Local Irritation
  • Local Pain

Contraindications and Warnings:

None mentioned. 

Dyclonine: Drug Interaction

Note: Drug Interaction Categories:

• Risk Factor C: Monitor When Using Combination
• Risk Factor D: Consider Treatment Modification
• Risk Factor X: Avoid Concomitant Use

Monitoring parameters:

Monitor for the response to treatment, cough reflex and gag reflex.

How to administer Dyclonine (Sucrets)?

It is administered as oral lozenges. The oral lozenges should be allowed to slowly dissolve in mouth. 

Mechanism of action of Dyclonine (Sucrets):

• A local anesthetic that produces reversible loss of sensation by preventing or diminishing the conduction of nerve impulses near the application site is typically referred to as a "topical anesthetic.

• " These anesthetics work by blocking the sodium channels on the nerve fibers, which prevents the transmission of pain signals.

• They are applied directly to the skin or mucous membranes to numb the area temporarily.

• Examples of topical anesthetics include lidocaine, benzocaine, and, as mentioned earlier, dyclonine.

International Brand names of Dyclonine [Ref]:

Dyclonine Brands Names in Pakistan:

• No Brands Available in Pakistan.