Famotidine (Pepcid) is an antihistamine that inhibits the H-2 histamine receptors in the stomach inhibiting acid secretion. It is used in the treatment and prevention of heartburn and peptic ulcer disease.
Famotidine Uses:
-
Oral:
-
Gastroesophageal reflux disease:
- Treatment of gastroesophageal reflux disease (GERD) and esophagitis secondary to GERD.
-
Heartburn (OTC only):
- heartburn, acid indigestion, and sour stomach.
-
Peptic ulcer disease:
- Treatment of active duodenal or gastric ulcers.
-
Note: Even though a labeled indication, proton pump inhibitors (PPIs) are considered the standard of care for treatment of peptic ulcer disease (PUD) rather than H-2-receptor antagonists (eg, famotidine) (Lanas 2017; Vakil 2019).
-
Injection:
-
Patients not able to take oral medication:
- For patients who cannot take orally
-
Off-Label Use of Famotidine in Adults:
- Aspiration prophylaxis in patients undergoing anesthesia
- Chronic spontaneous urticaria
- Infusion reaction, premedication
- Mastocytosis
- Stress ulcer prophylaxis in select critically ill patients
-
Famotidine (Pepcid) Dose in Adults
Famotidine (Pepcid) Dose in the Aspiration prophylaxis in patients undergoing anesthesia (off-label):
Note: can be used in patients high risk for aspiration:
- IV: 20 mg as a single dose ~40 to 60 minutes before inducing anesthesia;
- It can be combined with rapid-acting nonparticulate antacid (eg, oral sodium citrate and citric acid) and/or metoclopramide.
Famotidine (Pepcid) Dose in the treatment of chronic spontaneous urticaria as an alternative agent (adjunct) (off-label):
Note: Used as an adjunct if poor response to full-dose H-1 antihistamine.
- Oral: 20 mg twice daily combined with H-1 antihistamine;
- Wait for 2 to 4 weeks to measure the appropriate response.
Famotidine (Pepcid) Dose in the treatment of Gastroesophageal reflux disease:
-
Initial therapy:
-
Mild and intermittent symptoms (<2 episodes/week), and no evidence of erosive esophagitis:
-
Note: For much serious or recurring initial symptoms, with or without proof of erosive esophagitis, a proton pump inhibitor (PPI) as initial therapy is recommended.
- Oral: 10 mg twice daily as needed; if symptoms persist after 2 to 4 weeks, increase to 20 mg twice daily for 2 weeks; if symptoms improve, may continue therapy as needed.
Note: If symptoms persist after 2 weeks of 20 mg twice daily, discontinue and consider PPI therapy.
Famotidine (Pepcid) Dose in the treatment of Residual acid reflux symptoms despite maximal PPI therapy (adjunct):
- Oral: 20 mg one time each day given before sleep in addition to PPI therapy.
- The dose may also be administered intermittently or on-demand with scheduled PPI.
-
OTC labeling (patient-guided therapy):
- Heartburn, mild intermittent symptoms: Oral: 10 to 20 mg up to two times a day when needed (maximum: 40 mg/day); may also be taken 10 to 60 minutes before meals or drinks that initiate heartburn (maximum: 40 mg/day).
Famotidine (Pepcid) Dose for premedication in Infusion reactions (adjunct) (off-label):
- IV, Oral: 20 mg usually administered 30 to 60 minutes prior to infusion of certain chemotherapy agents or biologics;
- It is mostly given in combination with an H-1 antihistamine (eg, diphenhydramine) and glucocorticoid (refer to institutional protocols).
Famotidine (Pepcid) Dose in the treatment of Mastocytosis (adjunct):
- Oral: 10 to 20 mg every 12 hours modified to attain GI symptom relief.
- Typically consumed with other appropriate agents (eg, H-1 antihistamine and/or leukotriene inhibitor).
Famotidine (Pepcid) Dose for Stress ulcer prophylaxis in selected critically ill patients:
Note: For ICU patients with linked risk factors for GI bleeding (including coagulopathy, mechanical ventilation for >48 hours, traumatic brain injury, history of GI ulceration or bleeding within the past year, extensive burns); suspend prophylaxis when the risk factors are resolved.
- Oral or via nasogastric (NG) tube (alternative to enteral PPI):
- 20 mg twice a day.
- IV:
- 20 mg twice a day.
Famotidine (Pepcid) Dose in Childrens
Famotidine (Pepcid) Dose in the treatment of GERD:
-
Oral:
-
Suspension:
- Infants <3 months:
- 0.5 mg/kg/dose one time each day for up to 8 weeks;
- If not effective after 2 weeks, increase the dose to 1 mg/kg/dose one time a day is suggested.
- Infants ≥3 months, Children, and Adolescents ≤16 years:
- Initial: 0.5 mg/kg/dose two times a day;
- The maximum dose is 40 mg/dose;
- Doses up to 1 mg/kg/dose two times a day have been reported.
- Infants <3 months:
-
Tablets:
- Children and Adolescents ≥40 kg:
- 20 mg twice a day for up to 6 weeks;
- For esophagitis and additional symptoms due to GERD, may use 20 to 40 mg twice a day for up to 12 weeks
- Children and Adolescents ≥40 kg:
-
-
IV:
- Infants <3 months:
- 0.25 mg/kg/dose once each day;
- The dose based on a pharmacokinetic study that included 7 patients <3 months who were given IV famotidine.
- Infants ≥3 months:
- Initial: 0.25 mg/kg/dose every 12 hours;
- The maximum dose is 20 mg/dose;
- The dose is based on a pharmacokinetic study that included 11 patients >3 to 12 months who received IV famotidine.
- Children and Adolescents:
- Initial: 0.25 mg/kg/dose every 12 hours;
- The maximum dose: 20 mg/dose;
- Doses up to 0.5 mg/kg/dose every 12 hours have been reported
- Infants <3 months:
Famotidine (Pepcid) Dose in the treatment of Heartburn, acid indigestion, or sour stomach (OTC labeling):
-
Children ≥12 years and Adolescents:
- Oral: 10 to 20 mg after every 12 hours;
- The dose can be taken 15 to 60 minutes before eating food that causes heartburn;
- The maximum daily dose is 2 tablets/day (20 to 40 mg dependent upon OTC product)
Famotidine (Pepcid) Dose in the treatment of pathological hypersecretory conditions (eg, Zollinger-Ellison):
-
Adolescents ≥17 years:
- Oral: Initial: 20 mg every 6 hours, may increase up to 160 mg every 6 hours
- IV: 20 mg every 12 hours
Famotidine (Pepcid) Dose in the treatment of Peptic ulcer disease:
-
Oral:
- Suspension: Children and Adolescents ≤16 years:
- 0.5 mg/kg/day before sleeping or divided twice each day;
- The maximum daily dose is 40 mg/day;
- Doses up to 1 mg/kg/day at bedtime or distributed twice daily have been consumed.
- Suspension: Children and Adolescents ≤16 years:
-
Tablets:
-
Children and Adolescents >40 kg:
- Duodenal ulcer: Acute therapy: 40 mg once a day before sleep or 20 mg two times daily for 4 to 8 weeks
- Gastric ulcer: Acute therapy: 40 mg once a day at bedtime for up to 8 weeks
-
-
IV:
- Children and Adolescents:
- Initial: 0.25 mg/kg/dose every 12 hours;
- The maximum dose: 20 mg/dose;
- Doses up to 0.5 mg/kg/dose every 12 hours is reported
- Children and Adolescents:
Famotidine (Pepcid) Dose for the prophylaxis of stress ulcers, gastric acid suppression:
-
Infants, Children, and Adolescents:
- IV: 1 to 2 mg/kg/day in divided doses every 8 to 12 hours;
- The maximum daily dose is 40 mg/day.
Famotidine Pregnancy Risk Category: B
- Famotidine passes the placental barrier.
- The renal clearance of famotidine may be affected by pregnancy-related physiological changes.
- Histamine H antagonists were evaluated for the treatment and prevention of gastroesophageal acid disease (GERD), in pregnancy.
- For initial therapy, agents other than famotidine might be preferred.
- For aspiration prophylaxis, you can take histamine H antagonists before a cesarean birth.
Famotidine use during breastfeeding:
- Breast milk contains Famotidine.
- When famotidine was compared to a therapeutic infant dose of 0.5 mg/kg/day, the relative infant dose (RID), of 2.2% was determined. This is based on the peak breastmilk concentration.
- When the RID of the medication is less than 10%, breastfeeding can be considered satisfactory.
- The RID of Famotidine was determined using a milk content of 0.072 mg/mL. This gives an estimated daily infant dose via breastmilk of 0.011 mg/kg/day.
- The mother administered a single dose orally of 40 mg famotidine to her milk.
- According to the manufacturer breastfeeding should be considered during therapy.
- One must consider the risks of infant exposure as well as the benefits to the mother from breastfeeding.
- Famotidine is a preferred agent when treatment with a histamine H antagonist must be done. This is due to the lower concentrations of famotidine in breast milk.
Famotidine (Pepcid) Dose in Kidney Disease:
-
Injection:
- CrCl ≥50 mL/minute: No dosage adjustment required.
- CrCl <50 mL/minute: Administer 50% of dose or increase the interval to every 36 to 48 hours.
-
Oral:
-
Active duodenal ulcer:
- CrCl 30 to 60 mL/minute: Maximum dose: 20 mg one time daily or 40 mg every other day.
- CrCl <30 mL/minute: Maximum dose: 20 mg on alternate day or 10 mg once a day.
-
Maintenance of duodenal ulcer:
- CrCl 30 to 60 mL/minute: Maximum dose: 20 mg on alternate day or 10 mg once daily
- CrCl <30 mL/minute: Maximum dose: 10 mg every other day
-
Gastric ulcer:
- CrCl 30 to 60 mL/minute: Maximum dose: 20 mg once each day or 40 mg on alternate day
- CrCl <30 mL/minute: Maximum dose: 20 mg every other day or 10 mg once daily
-
GERD:
- Esophagitis and accompanying symptoms due to GERD:
- CrCl 30 to 60 mL/minute:
- The maximum dose for the 20 mg twice-daily regimen: 20 mg once daily or 40 mg every alternate day
- The maximum dose for the 40 mg twice-daily regimen: 40 mg once every day
- CrCl <30 mL/minute:
- The maximum dose for the 20 mg twice-daily regimen: 20 mg every other day or 10 mg once a day
- The maximum dose for the 40 mg two times in daily routine: 20 mg one time a day
- CrCl 30 to 60 mL/minute:
- Treatment of GERD (short-term):
-
- CrCl 30 to 60 mL/minute: Maximum dose: 20 mg one time a day
- CrCl <30 mL/minute: Maximum dose: 20 mg on alternate day or 10 mg once a day
-
- Pathological hypersecretory conditions: Avoid use
- Esophagitis and accompanying symptoms due to GERD:
-
Dose in Liver Disease:
There are no dosage adjustments given in the manufacturer's labeling.
All reported adverse drug reactions are for the oral formulations unless otherwise noted.
Common Side Effects of Famotidine (Pepcid):
-
Central nervous system:
- Agitation
Less Common Side Effects of Famotidine (Pepcid):
-
Central nervous system:
- Headache
- Dizziness
-
Gastrointestinal:
- Diarrhea
- Constipation
- Necrotizing enterocolitis
-
Local:
- Irritation at the injection site
Contraindications to Famotidine Include:
Severe hypersensitivity (eg anaphylaxis), to famotidine or other H-2 antagonists or any component of this formulation.
OTC labeling
- Use OTC for self-medication. Do not use OTC if you experience difficulty or pain while ingesting food, nausea, vomiting, bloody or black stool.
- Other acid reducers may cause allergic reactions
- Renal impairment
- Coadministration with acid reducers
Warnings and precautions
-
ECG changes
- Patients with mild-to-severe renal impairment have been reported to experience prolonged QT intervals.
- FDA received reports about torsades-de-pointes that were caused by famotidine.
-
Vitamin B 12 deficiency:
- Long-term treatment (>=2 year) can lead to vitamin B12 malabsorption and then vitamin B12 deficiency.
- The severity of the deficiency depends on the dose. It is more severe in women than in men (30 years). Prevalence decreases after stopping therapy.
-
Gastric cancer:
- The presence of gastric cancer is not exempted from treatment.
-
Renal impairment
- Take caution; there is a greater risk of CNS adverse effects and QT prolongation.
- Dosage adjustment is recommended for mild and chronic renal impairment (CrCl =60mL/minute).
Famotidine: Drug Interaction
Note: Drug Interaction Categories:
- Risk Factor C: Monitor When Using Combination
- Risk Factor D: Consider Treatment Modification
- Risk Factor X: Avoid Concomitant Use
Risk Factor C (Monitor therapy) |
|
| Cefpodoxime | Histamine H2 Receptor Antagonists may decrease the absorption of Cefpodoxime. Separate oral doses by at least 2 hours. |
| Cysteamine (Systemic) | Histamine H2 Receptor Antagonists may diminish the therapeutic effect of Cysteamine (Systemic). |
| Dexmethylphenidate | Histamine H2 Receptor Antagonists may increase the absorption of Dexmethylphenidate. Specifically, H2-antagonists may interfere with the normal release of drug from the extended-release capsules (Focalin XR brand), which could result in both increased absorption (early) and decreased delayed absorption. |
| Erdafitinib | May increase the serum concentration of OCT2 Substrates. |
| Fosamprenavir | Histamine H2 Receptor Antagonists may decrease the serum concentration of Fosamprenavir. Cimetidine may also inhibit the metabolism of the active metabolite amprenavir, making its effects on fosamprenavir/amprenavir concentrations difficult to predict. |
| Indinavir | Histamine H2 Receptor Antagonists may decrease the serum concentration of Indinavir. |
| Iron Salts | Histamine H2 Receptor Antagonists may decrease the absorption of Iron Salts. Exceptions: Ferric Carboxymaltose; Ferric Citrate; Ferric Gluconate; Ferric Hydroxide Polymaltose Complex; Ferric Pyrophosphate Citrate; Ferumoxytol; Iron Dextran Complex; Iron Isomaltoside; Iron Sucrose. |
| Methylphenidate | Histamine H2 Receptor Antagonists may increase the absorption of Methylphenidate. Specifically, H2-antagonists may interfere with the normal release of drug from the extended-release capsules (Ritalin LA brand), which could result in both increased absorption (early) and decreased delayed absorption. |
| Multivitamins/Minerals (with ADEK, Folate, Iron) | Histamine H2 Receptor Antagonists may decrease the serum concentration of Multivitamins/Minerals (with ADEK, Folate, Iron). Specifically, the absorption of iron may be impaired by H2-antagonists. |
| Nelfinavir | Histamine H2 Receptor Antagonists may decrease the serum concentration of Nelfinavir. Concentrations of the active M8 metabolite may also be reduced. |
| Saquinavir | Histamine H2 Receptor Antagonists may increase the serum concentration of Saquinavir. |
| Varenicline | Histamine H2 Receptor Antagonists may increase the serum concentration of Varenicline. Management: Monitor for increased varenicline adverse effects with concomitant use of cimetidine or other H2-antagonists, particularly in patients with severe renal impairment. International product labeling recommendations vary. Consult appropriate labeling. |
| Velpatasvir | Histamine H2 Receptor Antagonists may decrease the serum concentration of Velpatasvir. |
Risk Factor D (Consider therapy modification) |
|
| Acalabrutinib | Histamine H2 Receptor Antagonists may decrease the serum concentration of Acalabrutinib. Management: To minimize the potential for a significant interaction, separate administration of these agents by giving acalabrutinib 2 hours before ingestion of a histamine-2 receptor antagonist. |
| Atazanavir | Histamine H2 Receptor Antagonists may decrease the serum concentration of Atazanavir. Management: Specific dose limitations and administration guidelines exist; consult full interaction monograph or atazanavir prescribing information. |
| Bosutinib | Histamine H2 Receptor Antagonists may decrease the serum concentration of Bosutinib. Management: Administer histamine H2 receptor antagonists more than 2 hours before or after bosutinib. |
| Cefditoren | Histamine H2 Receptor Antagonists may decrease the serum concentration of Cefditoren. Management: Concomitant use of cefditoren with H2-antagonists and antacids is not recommended. Consider alternative methods to control acid reflux (eg, diet modification) or alternative antimicrobial therapy if use of H2-antagonists can not be avoided. |
| Dacomitinib | Histamine H2 Receptor Antagonists may decrease the serum concentration of Dacomitinib. Management: Administer dacomitinib at least 6 hours before or 10 hours after an histamine H2-receptor antagonist (H2RA). |
| Erlotinib | Histamine H2 Receptor Antagonists may decrease the serum concentration of Erlotinib. Management: Avoid H2-antagonists in patients receiving erlotinib when possible. If concomitant treatment cannot be avoided, erlotinib should be dosed once daily, 10 hours after and at least 2 hours before H2-antagonist dosing. |
| Gefitinib | Histamine H2 Receptor Antagonists may decrease the serum concentration of Gefitinib. Management: Administer gefitinib at least 6 hours before or after administration of a histamine H2-antagonist, and closely monitor clinical response to gefitinib. |
| Itraconazole | Histamine H2 Receptor Antagonists may increase the serum concentration of Itraconazole. Histamine H2 Receptor Antagonists may decrease the serum concentration of Itraconazole. Management: Administer Sporanox brand itraconazole at least 2 hours before or 2 hours after administration of any histamine H2 receptor antagonists (H2RAs). Exposure to Tolsura brand itraconazole may be increased by (H2RAs); consider itraconazole dose reduction. |
| Ketoconazole (Systemic) | Histamine H2 Receptor Antagonists may decrease the serum concentration of Ketoconazole (Systemic). Management: Administer oral ketoconazole at least 2 hours prior to use of any H2-receptor antagonist. Monitor patients closely for signs of inadequate clinical response to ketoconazole. |
| Ledipasvir | Histamine H2 Receptor Antagonists may decrease the serum concentration of Ledipasvir. |
| Mesalamine | Histamine H2 Receptor Antagonists may diminish the therapeutic effect of Mesalamine. Histamine H2-Antagonist-mediated increases in gastrointestinal pH may cause the premature release of mesalamine from specific sustained-release mesalamine products. Management: Consider avoiding concurrent administration of high-dose histamine H2-receptor antagonists with sustained-release mesalamine products. |
| Nilotinib | Histamine H2 Receptor Antagonists may decrease the serum concentration of Nilotinib. Management: The nilotinib dose should be given 10 hours after or 2 hours before the H2 receptor antagonist in order to minimize the risk of a significant interaction. |
| Posaconazole | Histamine H2 Receptor Antagonists may decrease the serum concentration of Posaconazole. Management: Avoid concurrent use of oral suspension with H2-antagonists whenever possible. Monitor patients closely for decreased antifungal effects if this combination is used. Delayed-release posaconazole tablets may be less likely to interact. |
| Rilpivirine | Histamine H2 Receptor Antagonists may decrease the serum concentration of Rilpivirine. Management: Administer histamine H2 receptor antagonists at least 12 hours before or 4 hours after rilpivirine. |
| Secretin | Histamine H2 Receptor Antagonists may diminish the diagnostic effect of Secretin. Specifically, use of H2-Antagonists may cause a hyper-response in gastrin secretion in response to secretin stimulation testing, falsely suggesting gastrinoma. Management: Avoid concomitant use of histamine H2-antagonists (H2RAs) and secretin. Discontinue H2RAs at least 2 days prior to secretin administration. |
| Tafenoquine | May increase the serum concentration of OCT2 Substrates. Management: Avoid use of OCT2 substrates with tafenoquine, and if the combination cannot be avoided, monitor closely for evidence of toxicity of the OCT2 substrate and consider a reduced dose of the OCT2 substrate according to that substrate's labeling. |
Risk Factor X (Avoid combination) |
|
| Cefuroxime | Histamine H2 Receptor Antagonists may decrease the absorption of Cefuroxime. Separate oral doses by at least 2 hours. |
| Dasatinib | Histamine H2 Receptor Antagonists may decrease the absorption of Dasatinib. Management: Antacids (taken 2 hours before or after dasatinib administration) can be used in place of H2-antagonists if some acid-reducing therapy is needed. |
| Delavirdine | Histamine H2 Receptor Antagonists may decrease the serum concentration of Delavirdine. Management: Chronic therapy with H2-antagonists should be avoided in patients who are being treated with delavirdine. The clinical significance of short-term H2-antagonist therapy with delavirdine is uncertain, but such therapy should be undertaken with caution. |
| Neratinib | Histamine H2 Receptor Antagonists may decrease the serum concentration of Neratinib. Specifically, histamine H2 receptor antagonists may reduce neratinib absorption. Management: Administer neratinib at least 2 hours before or 10 hours after administration of a histamine H2 receptor antagonist to minimize the impact of this interaction. |
| PAZOPanib | Histamine H2 Receptor Antagonists may decrease the serum concentration of PAZOPanib. Management: Avoid the use of histamine H2-antagonists in combination with pazopanib. Strategies to minimize the expected interaction between these agents (eg, dose separation) have not been investigated. |
| Risedronate | Histamine H2 Receptor Antagonists may increase the serum concentration of Risedronate. This applies specifically to delayed-release risedronate. |
Monitoring parameters:
- CBC,
- gastric pH,
- Occult blood with GI bleeding
How to administer Famotidine (Pepcid)?
IV push:
- Administer over at least 2 minutes.
Solution for infusion:
- Administer over 15 to 30 minutes.
Oral:
- Administer without regard to meals. May administer with antacids.
Suspension:
- Shake vigorously before use.
Tablet (OTC):
- Do not chew.
- To prevent symptoms, administer 10 to 60 minutes before eating food or drinking beverages known to cause heartburn.
Mechanism of action of Famotidine (Pepcid):
It inhibits competitively histamine at H-1 receptors in the gastric parietal cell cells. This inhibits gastric acid production.
The onset of action when orally administered: Antisecretory effect:
- Within 1 hour
Peak antisecretory effect:
- Oral: Within 1 to 3 hours (dose-dependent);
- IV: Within 30 minutes
The duration of its antisecretory effect:
- IV, Oral: 10 to 12 hours
Absorption when administered orally:
- Incompletely absorbed
Protein binding:
- 15% to 20%
Metabolism:
- 30% to 35%;
- It has minimal first-pass metabolism and forms one metabolite (S-oxide)
Bioavailability when administered orally:
- 40% to 45%
Half-life elimination:
- IV:
- Infants: ≤3 months: 8.1 ± 3.5 hours to 10.5 ± 5.4 hours;
- Infants >3 to 12 months: 4.5 ± 1.1 hours
- Children <11 years: 3.38 ± 2.6 hours
- Children ≥11 years and Adolescents ≤15 years: 2.3 ± 0.4 hours
- Adults: 2.5 to 3.5 hours;
- The half-life is prolonged with renal impairment;
- Oliguria: >20 hours;
- Anuria: 24 hours
Time to peak, serum:
- Oral: About 1 to 3 hours
Excretion:
- Urine (25% to 30% when administered orally, 65% to 70% when administered IV as unchanged drug).
International Brand Names of Famotidine:
- Acid Controller Max St
- Acid Controller Original Str
- Acid Reducer Maximum Strength
- Acid Reducer
- Heartburn Relief Max St
- Heartburn Relief
- Pepcid
- Pepcid AC Maximum Strength
- ALTI-Famotidine
- APO-Famotidine
- BCI-Famotidine
- CO Famotidine
- Famotidine Omega W-O Preserv
- Famotidine Omega W-Preserv
- GMD-Famotidine
- MYLAN-Famotidine
- NTP-Famotidine
- TEVA-Famotidine
- Acifam
- Androtin
- Antiflam
- Antodine
- Aulzadin
- Ausfam
- Bestidine
- Corocyd
- Denufam
- Durater
- Facid
- Facidex
- Fadin
- Fadine
- Fadul
- Famagen
- Famatel
- Famo
- Famoc
- Famocid
- Famodar
- Famodil
- Famodin
- Famodine
- Famogal
- Famogard
- Famonerton
- Famopsin
- Famosan
- Famosia
- Famotaz
- Famotec
- Famotid
- Famotin
- Famowal
- Famox
- Famozol
- Faradin
- Farotin
- Ferotine
- Fibonel
- Fudone
- Fuweidin
- Gasafe
- Gasmodin
- Gaster
- Gastren
- Gastridin
- Gastril
- Gastrium
- Gastro
- Gastrodomina
- Gastrum
- H2 Bloc
- Hista-Bloc
- Interfam
- Keamotin
- Kimodin
- Logos
- Ludex
- Modin
- Motiax
- Motidin
- Navatac
- Nulcerin
- Nulcex
- Pamacid
- Pepcid
- Pepcid AC
- Pepcidac
- Pepcidin
- Pepcidina
- Pepcidine
- Pepdif
- Pepdine
- Pepfamin
- Peptifam
- Peptoci
- Pepzan
- Pharmotidine
- Quamatel
- Quamtel
- Sedanium-R
- Snow
- Stadin
- Stomax
- Supertidine
- Tarpan
- Tismafam
- Topcid
- Ulcatif
- Ulcelac
- Ulcenol
- Ulceran
- Ulfadin
- Ulfagel
- Ulfamid
- Ulmo
- Vesmo-20
- Voker
- Weimok
- Winiful
- Yamadin
Famotidine Brand Names in Pakistan:
Famotidine Injection 20 Mg in Pakistan |
|
| Pepgen | Fassgen Pharmaceuticals |
Famotidine Injection 40 Mg in Pakistan |
|
| Famot-40 | Shaigan Pharmaceuticals (Pvt) Ltd |
Famotidine Syrup 10 Mg in Pakistan |
|
| Famgic | Goodman Laboratories |
Famotidine Syrup 10 Mg/5ml in Pakistan |
|
| Apsin | Saffron Pharmaceutical Company |
Famotidine Suspension 10 Mg in Pakistan |
|
| Famoday | Max Pharmaceuticals |
| Maripep | Miracle Pharmaceuticals(Pvt) Ltd |
Famotidine Suspension 10 Mg/5ml in Pakistan |
|
| Acicon | Barrett Hodgson Pakistan (Pvt) Ltd. |
| Acicon | Barrett Hodgson Pakistan (Pvt) Ltd. |
| Acidrol | Medisearch Pharmacal(Pvt) Ltd |
| Cantil | Helicon Pharmaceutek Pakistan (Pvt) Ltd. |
| Capcid | Olive Laboratories |
| Fadiphine | Global Pharmaceuticals |
| Fagastril | Gray`S Pharmaceuticals |
| Fam Ph | Evergreen Pharmaceuticals Pvt Limited |
| Fambria | Ambrosia Pharmaceuticals |
| Famcare | Care Pharmaceuticals |
| Famdin | Pakistan Pharmaceutical Products (Pvt) Ltd. |
| Famo Rains | Mac & Rans Pharmaceuticals (Pvt) Ltd |
| Famobex | Cibex (Private) Limited |
| Famorax | Mediceena Pharma (Pvt) Ltd. |
| Famoscot | Scotmann Pharmaceuticals |
| Famot | Shaigan Pharmaceuticals (Pvt) Ltd |
| Famotidine | Lawrence Pharma |
| Famron | P.D.H. Pharmaceuticals (Pvt) Ltd. |
| Famtac | Rasco Pharma |
| Famtaza | Zafa Pharmaceutical Laboratories (Pvt) Ltd. |
| Fastine | Trigon Pharmaceuticals Pakistan (Pvt) Ltd. |
| Fedcid | Fedro Pharmaceutical |
| Femas | Pearl Pharmaceuticals |
| Fomen | Shrooq Pharmaceuticals |
| G-Met | Tabros Pharma |
| Gastridine | Tg Pharma |
| Gepep | Akson Pharmaceuticals (Pvt) Ltd. |
| Gimed | Albro Pharma |
| Jevity | Wilshire Laboratories (Pvt) Ltd. |
| Kamcid | Bloom Pharmaceuticals (Pvt) Ltd. |
| Loacid | Raazee Theraputics (Pvt) Ltd. |
| Neofam | Neo Medix |
| Neutidin | Neutro Pharma (Pvt) Ltd. |
| Nogacid | Lowitt Pharmaceuticals (Pvt) Ltd |
| Pepcimed | Medicraft Pharmaceuticals (Pvt) Ltd. |
| Pepdine | Lotus Pharmaceuticals (Pvt) Ltd |
| Peptiban | Werrick Pharmaceuticals |
| Pharmotidine | Epharm Laboratories |
| Polypep | Wilsons Pharmaceuticals |
| Recid | Regent Laboratories Ltd. |
| Reducid | Platinum Pharmaceuticals (Pvt.) Ltd. |
| Servipep | Polyfine Chempharma (Pvt) Ltd. |
| Ulcenil | Siza International (Pvt) Ltd. |
Famotidine Suspension 40 Mg/5ml in Pakistan |
|
| Zepsin | Cirin Pharmaceuticals (Pvt) Ltd. |
Famotidine Tablets 10 Mg in Pakistan |
|
| Bepsin | Benson Pharamceuticals. |
| Chewfam | Atco Laboratories Limited |
| Femme | Batala Pharmaceuticals. |
| Fomicid | Himont Pharmaceuticals (Pvt) Ltd. |
| Hiler | Muller & Phipps Pakistan (Pvt) Ltd. |
| Nobar Chewable | Caylex Pharmaceuticals (Pvt) Ltd. |
| Peptiban | Werrick Pharmaceuticals |
| Peptiban-Ac | Werrick Pharmaceuticals |
| Reducid | Platinum Pharmaceuticals (Pvt.) Ltd. |
| U-Fit | Panacea Pharmaceuticals |
Famotidine Tablets 20 Mg in Pakistan |
|
| Acicon | Barrett Hodgson Pakistan (Pvt) Ltd. |
| Afomit | Alliance Pharmaceuticals (Pvt) Ltd. |
| Altad | Alson Pharmaceuticals |
| Apsin | Saffron Pharmaceutical Company |
| Ardfame | Ardin Pharmaceuticals |
| Atodine | Macquins International |
| Basil | Sycom Pharmaceuticals |
| Bepsin | Benson Pharamceuticals. |
| Brimdin | Rasco Pharma |
| Cantil | Helicon Pharmaceutek Pakistan (Pvt) Ltd. |
| Capcid | Olive Laboratories |
| Concid | Reko Pharmacal (Pvt) Ltd. |
| Curofam | Mega Pharmaceuticals (Pvt) Ltd |
| Ducid | Glaxosmithkline |
| Facid | Shafaz Pharma International (Pvt) Ltd. |
| Fadiphine | Global Pharmaceuticals |
| Fagastril | Gray`S Pharmaceuticals |
| Famcidine | Webros Pharmaceuticals |
| Famdin | Pakistan Pharmaceutical Products (Pvt) Ltd. |
| Famid | Wilshire Laboratories (Pvt) Ltd. |
| Famitine | Efroze Chemical Industries (Pvt) Ltd. |
| Famobex | Cibex (Private) Limited |
| Famocin | Navegal Laboratories |
| Famodin | Drugs Inn Pakistan |
| Famodine | Neutro Pharma (Pvt) Ltd. |
| Famogen | Genera Pharmaceuticals |
| Famonon | Dr. Raza Pharma (Private) Limited |
| Famopep | Royal Consumer Manufacturing Company |
| Famopsin | High - Q International |
| Famorjine | Adfa San Pharmaceuticals. |
| Famoscot | Scotmann Pharmaceuticals |
| Famosib | Irza Pharma (Pvt) Ltd. |
| Famot-20 | Shaigan Pharmaceuticals (Pvt) Ltd |
| Famotop | Xenon Pharmaceuticals (Pvt) Ltd. |
| Famron | P.D.H. Pharmaceuticals (Pvt) Ltd. |
| Famtab | Zanctok Pharmaceuticals |
| Famtaza | Zafa Pharmaceutical Laboratories (Pvt) Ltd. |
| Famtine | Efroze Chemical Industries (Pvt) Ltd. |
| Famulcer | Swiss Pharmaceuticals (Pvt) Ltd. |
| Famus | Biogen Pharma |
| Fanitin | Europak Pharma (Pvt) Ltd |
| Fastine | Trigon Pharmaceuticals Pakistan (Pvt) Ltd. |
| Femas | Pearl Pharmaceuticals |
| Femme | Batala Pharmaceuticals. |
| Femoceran | Alina Combine Pharmaceuticals (Pvt) Ltd. |
| Femoceran | Alina Combine Pharmaceuticals (Pvt) Ltd. |
| Femodine | Neutro Pharma (Pvt) Ltd. |
| Fencid | Pharmacare Laboratories (Pvt) Ltd. |
| Flodin | Flow Pharmaceuticals (Pvt) Ltd. |
| Fm 20 | Hizat Pharmaceutical Industries (Pvt) Ltd. |
| Fomen | Shrooq Pharmaceuticals |
| Fomicid | Himont Pharmaceuticals (Pvt) Ltd. |
| Gaster | Hamaz Pharmaceutical (Pvt) Ltd. |
| Gastoch | Usawa Pharmaceuticals |
| Gastridine | Tg Pharma |
| Gimed | Albro Pharma |
| H2-Foz | Fozan Pharmaceuticals Industriers (Pvt) Ltd |
| H2bf | Rakaposhi Pharmaceutical (Pvt) Ltd. |
| H2bf | Rakaposhi Pharmaceutical (Pvt) Ltd. |
| H2f | Ferozsons Laboratoies Ltd. |
| Hepsin | Heal Pharmaceuticals Pvt Ltd |
| Hiler | Muller & Phipps Pakistan (Pvt) Ltd. |
| Hycocid | Bloom Pharmaceuticals (Pvt) Ltd. |
| Ispep | Medisure Laboratories Pakistan (Pvt.) Ltd. |
| Jevity | Wilshire Laboratories (Pvt) Ltd. |
| Jevity | Wilshire Laboratories (Pvt) Ltd. |
| Kalfot | Medera Pharmaceuticals (Pvt) Ltd. |
| Ketacid | Hygeia Pharmaceuticals |
| Kotidine | Al-Habib Pharmaceuticals. |
| Lyofam | Valor Pharmaceuticals |
| Mot | Jaens Pharma |
| Motn | Caraway Pharmaceuticals |
| Nencid | Nenza Pharmaceuticals (Pvt) Limited |
| Neofam | Neo Medix |
| No-Acid | Nova Med Pharmaceuticals |
| Nobar | Caylex Pharmaceuticals (Pvt) Ltd. |
| Nocer | Bryon Pharmaceuticals (Pvt) Ltd. |
| Nocid | Novartis Pharma (Pak) Ltd |
| Nogacid | Lowitt Pharmaceuticals (Pvt) Ltd |
| Novifam | Novins International |
| Optifam | Merck Private Ltd. |
| Panalba | R.Y. International |
| Pandona | Venture Chemical & Pharmaceuticals (Pvt) Ltd. |
| Pepcimed | Medicraft Pharmaceuticals (Pvt) Ltd. |
| Pepdine | Lotus Pharmaceuticals (Pvt) Ltd |
| Pepfin | Innvotek Pharmaceuticals |
| Pepgard | Elko Organization (Pvt) Ltd. |
| Pepmon | Shaheen Agencies |
| Peprax | Umersons |
| Peprid | Helix Pharma (Private) Limited |
| Peptiban | Werrick Pharmaceuticals |
| Peptiban Dispersible | Werrick Pharmaceuticals |
| Peptiloc | Bosch Pharmaceuticals (Pvt) Ltd. |
| Pitfam | Jinnah Pharmaceuticals |
| Polypep | Wilsons Pharmaceuticals |
| Prilosec | Aries Pharmaceuticals (Pvt) Ltd |
| Qincid | Qintar Pharmacuticals |
| Quamatel | Medimpex Scientific Office |
| Reducid | Platinum Pharmaceuticals (Pvt.) Ltd. |
| Ricer | Polyfine Chempharma (Pvt) Ltd. |
| So-Fem | Roryan Pharmaceutical Industries (Pvt) Ltd |
| Surfac | Meditech Pharmaceuticals |
| Tabrodine | Tabros Pharma |
| Tinopep | Remington Pharmaceutical Industries (Pvt) Ltd. |
| Tulip | Tagma Pharma (Pvt) Ltd. |
| U-Fit | Panacea Pharmaceuticals |
| Ul-Safe | Saydon Pharmaceutical Industries (Pvt) Ltd. |
| Ulcemal | Atco Laboratories Limited |
| Ulcenil | Siza International (Pvt) Ltd. |
| Ulcepep-20 | Epoch Pharmaceutical |
| Ulcepep-20 | Epoch Pharmaceutical |
| Ulciban | Star Laboratories (Pvt) Ltd. |
| Ulcofin | Pharmix Laboratories (Private) Limited. |
| Ulfam | Highnoon Laboratories Ltd. |
| Ulfarid | Davis Pharmaceutical Laboratories |
| Ulsin | Don Valley Pharmaceuticals (Pvt) Ltd. |
| Vefam | Vega Pharmaceuticals Ltd. |
| Volvic | Rotex Medica Pakistan (Pvt) Ltd |
| Welfam | Ferroza International Pharmaceuticals (Pvt) Ltd. |
| Welfam | Ferroza International Pharmaceuticals (Pvt) Ltd. |
| Yamadin | Bex Pharma (Pvt) Ltd. |
| Zebid | Atco Laboratories Limited |
| Zepsin | Cirin Pharmaceuticals (Pvt) Ltd. |
Famotidine Tablets 40 Mg in Pakistan |
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| Acicon | Barrett Hodgson Pakistan (Pvt) Ltd. |
| Afomit | Alliance Pharmaceuticals (Pvt) Ltd. |
| Aladin | Bio Pharma |
| Altad | Alson Pharmaceuticals |
| Apsin | Saffron Pharmaceutical Company |
| Ardfame | Ardin Pharmaceuticals |
| Atodine | Macquins International |
| Ban-Ulcer | Pakheim Internanational Pharma |
| Basil | Sycom Pharmaceuticals |
| Bepsin | Benson Pharamceuticals. |
| Brimdin | Rasco Pharma |
| Cantil | Helicon Pharmaceutek Pakistan (Pvt) Ltd. |
| Capcid | Olive Laboratories |
| Concid | Reko Pharmacal (Pvt) Ltd. |
| Curofam | Mega Pharmaceuticals (Pvt) Ltd |
| Delfamo-Z | Delta Pharma (Pvt) Ltd. |
| Dewrel Dispersible | English Pharmaceuticals Industries |
| Ducid | Glaxosmithkline |
| Duonol | Euro Pharma International |
| Efrel | English Pharmaceuticals Industries |
| Epidine | Zinta Pharmaceuticals Industries |
| Facid | Shafaz Pharma International (Pvt) Ltd. |
| Fadiphine | Global Pharmaceuticals |
| Fagastril | Gray`S Pharmaceuticals |
| Famace | Medera Pharmaceuticals (Pvt) Ltd. |
| Famcet | Friends Pharma (Pvt) Ltd |
| Famcidine | Webros Pharmaceuticals |
| Famdin | Pakistan Pharmaceutical Products (Pvt) Ltd. |
| Famid | Wilshire Laboratories (Pvt) Ltd. |
| Famitine | Efroze Chemical Industries (Pvt) Ltd. |
| Famobex | Cibex (Private) Limited |
| Famocin | Navegal Laboratories |
| Famodine | Neutro Pharma (Pvt) Ltd. |
| Famogem | Delux Chemical Industries |
| Famogen | Genera Pharmaceuticals |
| Famonon | Dr. Raza Pharma (Private) Limited |
| Famopep | Royal Consumer Manufacturing Company |
| Famopsin | High - Q International |
| Famorax | Mediceena Pharma (Pvt) Ltd. |
| Famorjine | Adfa San Pharmaceuticals. |
| Famosaf | Saaaf Pharmaceuticals |
| Famoscot | Scotmann Pharmaceuticals |
| Famosib | Irza Pharma (Pvt) Ltd. |
| Famosure | Medisure Laboratories Pakistan (Pvt.) Ltd. |
| Famot-40 | Shaigan Pharmaceuticals (Pvt) Ltd |
| Famotid | Amson Vaccines & Pharma (Pvt) Ltd. |
| Famotop | Xenon Pharmaceuticals (Pvt) Ltd. |
| Famowan | Nawan Laboratories (Pvt) Ltd. |
| Famron | P.D.H. Pharmaceuticals (Pvt) Ltd. |
| Famtab | Zanctok Pharmaceuticals |
| Famtaza | Zafa Pharmaceutical Laboratories (Pvt) Ltd. |
| Famtine | Efroze Chemical Industries (Pvt) Ltd. |
| Famulcer | Swiss Pharmaceuticals (Pvt) Ltd. |
| Famus | Biogen Pharma |
| Fanitin | Europak Pharma (Pvt) Ltd |
| Fapcid | Lexicon Pharmaceuticals (Pvt) Ltd. |
| Fd 40 | Tagma Pharma (Pvt) Ltd. |
| Feawel | Cherwel Pharmaceuticals (Pvt) Ltd |
| Fedcid | Fedro Pharmaceutical |
| Fedohit-40 | Unipharma (Pvt) Ltd. |
| Femas | Pearl Pharmaceuticals |
| Femme | Batala Pharmaceuticals. |
| Femoceran | Alina Combine Pharmaceuticals (Pvt) Ltd. |
| Femodine | Neutro Pharma (Pvt) Ltd. |
| Fencid | Pharmacare Laboratories (Pvt) Ltd. |
| Flodin | Flow Pharmaceuticals (Pvt) Ltd. |
| Flut 40 | Zephyr Pharmatec (Pvt) Ltd. |
| Fm 40 | Hizat Pharmaceutical Industries (Pvt) Ltd. |
| Fogo | Goodman Laboratories |
| Fomen | Shrooq Pharmaceuticals |
| Fomicid | Himont Pharmaceuticals (Pvt) Ltd. |
| Fotel | Ideal Pharmaceutical Industries |
| Fumota | Orta Labs. (Pvt) Ltd. |
| Gastapil | Danas Pharmaceuticals (Pvt) Ltd |
| Gaster | Hamaz Pharmaceutical (Pvt) Ltd. |
| Gastoch | Usawa Pharmaceuticals |
| Gastoch | Usawa Pharmaceuticals |
| Gastridine | Tg Pharma |
| Gastrodine | Harmann Pharmaceutical Laboratories (Pvt) Ltd. |
| Gd-Cid | 21st Century Pharmaceuticals Co. |
| Gepep | Akson Pharmaceuticals (Pvt) Ltd. |
| Gerdin | Global Pharmaceuticals |
| Gimed | Albro Pharma |
| H2-Foz | Fozan Pharmaceuticals Industriers (Pvt) Ltd |
| H2bf | Rakaposhi Pharmaceutical (Pvt) Ltd. |
| H2bf | Rakaposhi Pharmaceutical (Pvt) Ltd. |
| H2f | Ferozsons Laboratoies Ltd. |
| Hepsin | Heal Pharmaceuticals Pvt Ltd |
| Hiler | Muller & Phipps Pakistan (Pvt) Ltd. |
| Hodine | Honig Pharmaceuticals Laboratories |
| Hycocid | Bloom Pharmaceuticals (Pvt) Ltd. |
| Ispep | Medisure Laboratories Pakistan (Pvt.) Ltd. |
| Jevity | Wilshire Laboratories (Pvt) Ltd. |
| Jevity | Wilshire Laboratories (Pvt) Ltd. |
| Kalfot | Medera Pharmaceuticals (Pvt) Ltd. |
| Ketacid | Hygeia Pharmaceuticals |
| Kotidine | Al-Habib Pharmaceuticals. |
| Litz | Glitz Pharma |
| Lyofam | Valor Pharmaceuticals |
| Max-H2 | Makson Pharmaceuticals |
| Mot | Jaens Pharma |
| Motn | Caraway Pharmaceuticals |
| Nencid | Nenza Pharmaceuticals (Pvt) Limited |
| Neofam | Neo Medix |
| No-Acid | Nova Med Pharmaceuticals |
| No-Ul | Fynk Pharmaceuticals |
| Nobar | Caylex Pharmaceuticals (Pvt) Ltd. |
| Nocer | Bryon Pharmaceuticals (Pvt) Ltd. |
| Nocid | Novartis Pharma (Pak) Ltd |
| Nogacid | Lowitt Pharmaceuticals (Pvt) Ltd |
| Novifam | Novins International |
| Nutam | Robins Pharmaceutical Industries |
| Optifam | Merck Private Ltd. |
| Otofam | Genome Pharmaceuticals (Pvt) Ltd |
| Panalba | R.Y. International |
| Pandona | Venture Chemical & Pharmaceuticals (Pvt) Ltd. |
| Papcinil | Crest Pharmaceuticals |
| Pepcidine | Obs |
| Pepcifine | Semos Pharmaceuticals (Pvt) Ltd. |
| Pepcifine | Semos Pharmaceuticals (Pvt) Ltd. |
| Pepcimed | Medicraft Pharmaceuticals (Pvt) Ltd. |
| Pepciron | Mass Pharma (Private) Limited |
| Pepdine | Lotus Pharmaceuticals (Pvt) Ltd |
| Pepdis | Candid Pharmaceuticals |
| Pepfin | Innvotek Pharmaceuticals |
| Pepgard | Elko Organization (Pvt) Ltd. |
| Pepgen | Fassgen Pharmaceuticals |
| Pepmon | Shaheen Agencies |
| Pepnic | Dosaco Laboratories |
| Peprid | Helix Pharma (Private) Limited |
| Peptiban | Werrick Pharmaceuticals |
| Peptiban Dispersible | Werrick Pharmaceuticals |
| Peptiloc | Bosch Pharmaceuticals (Pvt) Ltd. |
| Pepton | Paramount Pharmaceuticals |
| Pharmotidine | Epharm Laboratories |
| Pitfam | Jinnah Pharmaceuticals |
| Placid | Pulse Pharmaceuticals |
| Polypep | Wilsons Pharmaceuticals |
| Prilosec | Aries Pharmaceuticals (Pvt) Ltd |
| Pulfame | Pulse Pharmaceuticals |
| Qincid | Qintar Pharmacuticals |
| Quamatel | Medimpex Scientific Office |
| Qucid-40 | Qureshi Pharma (Pvt) Ltd. |
| R-Cid | Silver Oak Corporation. |
| Recid | Regent Laboratories Ltd. |
| Reducid | Platinum Pharmaceuticals (Pvt.) Ltd. |
| Resid | Regent Laboratories Ltd. |
| Ricer | Polyfine Chempharma (Pvt) Ltd. |
| Sac-40 | Amass Enterprises |
| Servibet | Polyfine Chempharma (Pvt) Ltd. |
| Shaw | Shawan Pharmaceuticals |
| So-Fem | Roryan Pharmaceutical Industries (Pvt) Ltd |
| Stomachcare | Jawa Pharmaceuticals(Pvt) Ltd. |
| Surfac | Meditech Pharmaceuticals |
| Tabrodine | Tabros Pharma |
| Tagafam Dispersible | Tagma Pharma (Pvt) Ltd. |
| Tasofam | F.M. Pharmaceuticals International |
| Tifam | Drug Pharmaceuticals Chem. (Pvt). |
| Tinopep | Remington Pharmaceutical Industries (Pvt) Ltd. |
| Tulip | Tagma Pharma (Pvt) Ltd. |
| Ul Samark | Vital Mark Liboratories (Pvt) Ltd |
| Ul-Safe | Saydon Pharmaceutical Industries (Pvt) Ltd. |
| Ulcare | Z-Jans Pharmaceutical (Pvt) Ltd. |
| Ulcefame | Zephyr Pharmatec (Pvt) Ltd. |
| Ulcemal | Atco Laboratories Limited |
| Ulcenil | Siza International (Pvt) Ltd. |
| Ulcepep-40 | Epoch Pharmaceutical |
| Ulcerx | Hansel Pharmacueutical Pvt (Ltd) |
| Ulciban | Star Laboratories (Pvt) Ltd. |
| Ulcofin | Pharmix Laboratories (Private) Limited. |
| Ulfam | Highnoon Laboratories Ltd. |
| Ulfarid | Davis Pharmaceutical Laboratories |
| Ulsin | Don Valley Pharmaceuticals (Pvt) Ltd. |
| Vefam | Vega Pharmaceuticals Ltd. |
| Vie-D | Tagma Pharma (Pvt) Ltd. |
| Volvic | Rotex Medica Pakistan (Pvt) Ltd |
| Wisfa | Wise Pharmaceuticals (Pvt) Ltd |
| Xegerd | Navegal Laboratories |
| Yamadin | Bex Pharma (Pvt) Ltd. |
| Zebid | Atco Laboratories Limited |
| Zepsin | Cirin Pharmaceuticals (Pvt) Ltd. |
Famotidine Capsules 20 Mg in Pakistan |
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| Kamcid | Bloom Pharmaceuticals (Pvt) Ltd. |
Famotidine Capsules 40 Mg in Pakistan |
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| Kamcid | Bloom Pharmaceuticals (Pvt) Ltd. |
| Stolee | Flow Pharmaceuticals (Pvt) Ltd. |