Hydroxypropyl Methylcellulose Eye Drops

Hydroxypropyl methylcellulose (HPMC) is a cellulose derivative that is commonly used in various industries, including pharmaceuticals, food production, and construction. It is a polymer derived from cellulose, which is the main component of plant cell walls. HPMC is typically synthesized by treating cellulose with propylene oxide and methyl chloride.

Hydroxypropyl Methylcellulose Eye Drops act as a lubricant. It is used in the symptomatic treatment of patients with dry eyes as in patients with Sjogren's syndrome.

Hydroxypropyl methylcellulose Uses:

  • It is indicated for the relief of burning sensation in the eyes and minor irritation due to dry eyes.
  • It may also be used as a diagnostic agent in gonioscopic examination.

Hydroxypropyl Methylcellulose Eye Drops Dose in Adults

Hydroxypropyl Methylcellulose Eye Drops Dose in the treatment of dry eyes:

  • For the treatment, you just need to put 1 to 2 drops of the solution in the eye that feels dry whenever you need it.

Dose in Children:

Instill one or two drops as required.

Use in Pregnancy and breastfeeding:

The topical ocular application does not result in systemic absorption of the drug. It can be used in pregnant and lactating women.

Dose in Kidney disease:

No dosage adjustment is recommended in patients with kidney disease.

Dose in Liver disease:

No dosage adjustment is required.

Side effects of Hydroxypropyl Methylcellulose Eye Drops:

Patients may feel discomfort, redness, or itching in the eyes. Some patients may report visual changes and puffy eyelids.

Contraindications to Hydroxypropyl methylcellulose:

If someone has hypersensitivity to hydroxypropyl methylcellulose or any part of the product, it means they are overly sensitive or allergic to this substance or other ingredients in the formulation. In such cases, it is advisable to avoid using products containing hydroxypropyl methylcellulose to prevent allergic reactions.

Monitoring Parameters:

None mentioned.

How to administer Hydroxypropyl Methylcellulose Eye Drops?

  • It is administered every four to six hours or as needed.
  • The patients should be asked to wash their hands, tilt the head backwards, and instill the drops without touching the eyes or surround ing skin with the tip of the bottle.

Mechanism of action of Hydroxypropyl Methylcellulose Eye Drops:

It's used to moisten the cornea, eye surface, and lens. It can be used to replace tears in patients suffering from sicca syndrome (dry eye syndrome), and in Sjogren's patients.

International Brand Names of Hydroxypropyl methylcellulose:

  • GenTeal Mild to Moderate
  • GenTeal Mild
  • GenTeal Severe
  • Gonak
  • Goniosoft
  • Goniosol
  • Goniotaire
  • Goniovisc
  • ImproVue
  • Isopto Tears
  • Natural Balance Tears
  • Natures Tears
  • OcuCoat Viscoadherent
  • Pure & Gentle Lubricant
  • Systane Overnight Ther
  • Artelac
  • Artific
  • Bion Tears
  • Celulose Grin
  • Genteal
  • Hicel
  • Humalac B
  • Hydromoor
  • Hypromellose
  • Hypromol
  • Ilube
  • Isopto Plain
  • Isopto Tears
  • Lac-Oph
  • Lacrisic
  • Lacrisifi
  • Lacrystat
  • Lagrimas Artificiales
  • Methocel
  • Methopt Eye Drops
  • Meticel
  • Metilcellulosa
  • Miltear
  • Min Young
  • Moisol
  • Natear
  • Natear UD
  • Naturalag
  • Occucoat
  • Ocucoat
  • Ocucort
  • Ocufreshs
  • Opsil Tears
  • Optal Tears
  • OQ-Coat
  • Poly-Tears Eye Drops
  • Syseye
  • Tears Natural II
  • Tears Naturale
  • Tears Naturale II
  • Ultra Tears
  • Viscomet

Hydroxypropyl methylcellulose Brand Names in Pakistan:

Hydroxypropyl Methylcellulose Inj 2 %w/w in Pakistan


Ethical Laboratories (Pvt) Ltd.

Hydroxypropyl Methylcellulose Drops 3 mg/ml in Pakistan

Neo Tears

Vega Pharmaceuticals Ltd.

Hydroxypropyl Methylcellulose Eye Drops 2 %w/v in Pakistan


Novartis Pharma (Pak) Ltd


Farmigea Pak (Pvt) Ltd.


Ophth-Pharma (Pvt) Ltd.


Sante (Pvt) Limited


Sante (Pvt) Limited

Hydroxypropyl Methylcellulose 0.3 %w/v in Pakistan


Sante (Pvt) Limited

Hydroxypropyl Methylcellulose Eye Drops 0.5 %w/v in Pakistan


Remington Pharmaceutical Industries (Pvt) Ltd.


Neo Medix