Lactase (Lactaid) is a disaccharidase enzyme that converts lactose into glucose and galactose. It helps in the digestion of dairy products in patients who are lactose intolerant.
Lactase Uses:
-
Lactose intolerance:
- It is indicated in patients with lactose intolerance. It helps in the digestion of lactose that is the major component of milk.
Lactase Dose in Adults:
The dosage strength and frequency of administration vary according to the product. Specific product information should be consulted before prescribing the medicine.
Note:
- Patients who take milk or dairy products 30 to 45 minutes after taking the medicine may be advised additional servings.
Lactase Dose in the Lactose intolerance:
- Oral: It is administered orally 1 to 3 tablets with the first bite of milk or food containing dairy.
Use in children:
Refer to adults dosing.
Pregnancy Risk Category: N
- It has not been classified as a risk to pregnancy.
- It has not been tested in animal reproduction studies.
- If indicated, it can be used during pregnancy or breastfeeding.
Dose in Kidney Disease:
There are no dosage adjustments provided in the manufacturer's labeling.
Dose in Liver disease:
There are no dosage adjustments provided in the manufacturer's labeling.
Side effects of Lactase:
Side effects of the drug have not been mentioned. Case reports of allergic reactions to the drug have been documented in the literature. These include: Itching, hives, urticaria, rash, swelling of the face, tongue, and lips, difficulty breathing, and hypotension.
Contraindications to Lactase:
There have not been any contraindications. Patients who are allergic to the drug should not use it. It should also be used under certain conditions:
- Patients suffering from inflammatory bowel disease
- Short bowel syndrome
- Patients suffering from bacterial overgrowth
- People who have had a recent gastrointestinal surgery.
Monitoring Parameters:
Stool frequency and improvement in abdominal gases, flatulence, and diarrheal episodes should be monitored.
How to administer Lactase?
- It is best administered immediately before a meal that contain dairy products.
- It may also be mixed with milk or other dairy containing liquid meals immediately before administering it.
Mechanism of action of Lactase?
- Lactase is a disacharidase enzyme that converts Lactose into glucose and galactose.
- Glucose and galactose are monosacharides that are then easily digestible.
International Brand Names of Lactase:
- Lac-Dose
- Lactaid Fast Act
- Lactaid
- Lactase Enzyme
- Lactase Fast Acting
- Surelac
- Children's Lacteeze Original Formula
- Enzym laktaza
- Lactosanol
Lactase Brand Names in Pakistan:
No Brands Available in Pakistan.