Lactase (Lactaid) is a disaccharidase enzyme that converts lactose into glucose and galactose. It helps in the digestion of dairy products in patients who are lactose intolerant.

Lactase Uses:

• Lactose intolerance:

  • It is indicated in patients with lactose intolerance. It helps in the digestion of lactose that is the major component of milk.

Lactase Dose in Adults:

The dosage strength and frequency of administration vary according to the product. Specific product information should be consulted before prescribing the medicine.

Note:

• Patients who take milk or dairy products 30 to 45 minutes after taking the medicine may be advised additional servings.

Lactase Dose in the Lactose intolerance:

• Oral: It is administered orally 1 to 3 tablets with the first bite of milk or food containing dairy.

Use in children:

Refer to adults dosing.

Pregnancy Risk Category: N

• It has not been classified as a risk to pregnancy. 
• It has not been tested in animal reproduction studies.
• If indicated, it can be used during pregnancy or breastfeeding.

Dose in Kidney Disease:

There are no dosage adjustments provided in the manufacturer's labeling.

Dose in Liver disease:

There are no dosage adjustments provided in the manufacturer's labeling.

Side effects of Lactase:

Side effects of the drug have not been mentioned. Case reports of allergic reactions to the drug have been documented in the literature. These include: Itching, hives, urticaria, rash, swelling of the face, tongue, and lips, difficulty breathing, and hypotension.

Contraindications to Lactase:

There have not been any contraindications. Patients who are allergic to the drug should not use it. It should also be used under certain conditions:

• Patients suffering from inflammatory bowel disease
• Short bowel syndrome
• Patients suffering from bacterial overgrowth
• People who have had a recent gastrointestinal surgery.

Monitoring Parameters:

Stool frequency and improvement in abdominal gases, flatulence, and diarrheal episodes should be monitored.

How to administer Lactase?

• It is best administered immediately before a meal that contain dairy products.
• It may also be mixed with milk or other dairy containing liquid meals immediately before administering it.

Mechanism of action of Lactase?

• Lactase is a disacharidase enzyme that converts Lactose into glucose and galactose.
• Glucose and galactose are monosacharides that are then easily digestible.

International Brand Names of Lactase:

• Lac-Dose
• Lactaid Fast Act
• Lactaid
• Lactase Enzyme
• Lactase Fast Acting
• Surelac
• Children's Lacteeze Original Formula
• Enzym laktaza
• Lactosanol

Lactase Brand Names in Pakistan:

No Brands Available in Pakistan.