What percentage of fluid is retained in the intravascular compartment if you infuse the following solutions?
If 1000 ml of dextrose water is infused
2/3 will go into intracellular space : 660 ml
1/3 in extracellular space : 330 ml
Out of this 330 ml, 2/3 will go into interstitium and 1/3 intravascular.
So fluid going into interstitium: 220 ml
Fluid going intravascular: 110 ml
110/1000 ×100 : 11%
So 11% of dextrose water is retained intravascular.
If 1000 ml of normal saline is infused:.
N/S has 154 mmol/L of Na which is extracellular ion so the fluid will be distracted in extracellular compartment.
2/3 in interstitium :660 ml
1/3 intravascular: 330 ml
330/1000×100 : 33%
So 33 % of fluid will be retained intravascularly.
If 20% albumin is infused:
albumin will exert oecotic pressure and will keep fluid in intravascular space until colloid particles are removed by reticuloendothelial system. So infusion of 1 liter of colloid like albumin will add 1 liter to intravascularly space.