What are the most important investigations to order in this young girl with a palpable purpura?
When would you recommend corticosteroids?
Urine r/e(may show dysmorphic red blood cells and casts with an elevated protein:creatinine ratio)
serum iga levels
and other test to rule out other diagnosis
c3 c4 levels
if neurological findings
kidney biopsy (for mesengial iga deposits or cresents formation?
indication for steroids
Persistent nephrotic syndrome
Crescents in more than 50% of glomeruli
Severe abdominal pain
Substantial GI hemorrhage
Neurologic system involvement