Alclometasone cream is a low to medium-potency topical steroid used in the treatment of steroid-responsive skin disorders.
It possesses anti-inflammatory, antipruritic, and vasoconstrictive properties.
Aclovate (Alclometasone dipropionate) Uses:
- A topical steroid called alclometasone is used to treat many skin disorders including eczema, psoriasis, and others by reducing swelling, itching, dryness, and pain.
- It is also used to treat drug-induced skin reactions. However, it should not be used to treat acne and yeast infections.
- Steroids can worsen acne and infections, especially yeast infections.
- The application of alclometasone dipropionate, like other topical steroids, should be avoided over the face, genitals, armpits, and breasts.
Alclometasone dipropionate for adult Steroid-responsive dermatoses:
Topical: 1-2 times per day, apply a thin coating to the afflicted region.
Reassessment of the diagnosis may be required if the improvement is not apparent within 2 weeks after control is attained; therapy should be stopped at that point.
Use in children:
Children 1 year of age or older:
- 2-3 times each day, apply a thin coating to the afflicted region.
Note:
- If control is attained, stop the therapy. Consider a different diagnosis when reevaluating if progress is not evident.
- Do not use it for more than three weeks in children. Apply occlusive dressings for refractory and deep-seated skin disorders.
Pregnancy Risk Factor C
- Large portions of the body, lengthy periods of time, or excessive dosages of topical medications should not be used.
- Breastfeeding mothers should be cautious
Renal Dose:
- No dose adjustment is required.
Dose in Liver disease:
- No dose adjustment is required.
Alclometasone cream side effects:
Endocrine & metabolic:
- Cushing's syndrome
- Diabetes
- HPA axis suppression
- osteoporosis
- growth retardation4
- hypertension
Dermatologic:
- Acne
- hypopigmentation
- striae
- miliaria
- perioral dermatitis
- skin atrophy
- facial hair
Local side effects:
- burning
- erythema
- itching
- Dryness
- irritation
- papular rash
- folliculitis
Miscellaneous:
- Prolonged use may cause immunosuppression and Secondary infections can occur.
Contraindications to Alclometasone cream
- Hypersensitivity to any ingredient in the formulation, including alclometasone
- Apply over the face Apply to infected areas, such as yeast infections.
Monitor:
- Long-term steroid use can suppress the hypothalamic-pituitary axis.
- Cortisol and ACTH stimulation test may be done if it is suspected.
How to apply alclometasone cream?
- Exclusively for external usage. To clean, dry skin, apply a thin coating, and then gently massage it in.
- Keep your distance from the breasts, groyne, underarms, face, and eyes. If there are any open or weeping lesions present, they should not be utilised.
- Before and after using, wash your hands thoroughly.
Mechanism of Action of alclometasone dipropionate:
- suppresses the synthesis of the enzymes required to minimise inflammation, stop mitotic activity, and produceSvasoconstriction.
Absorption
- Topical: Approximately 3% of topical medications are absorbed into the body after 8 hours.
International brands of alclometasone dipropionate:
- Acloderm
- Aclosone
- Aclovate
- Almeta
- Cloderm
- Delonal
- Demiderm
- Legederm
- Logoderm
- Lomesone
- Miloderme
- Modraderm
- Modrasone
- Perderm
Brands in Pakistan:
No brands available in Pakistan.
 Injection.webp)