Glycerin, also spelled glycerine, is a colorless, odorless, and viscous liquid that is widely used in various industries. It has the chemical formula C3H8O3 and is a trihydric alcohol, meaning it contains three hydroxyl (OH) groups.

Glycerin is a colorless viscous liquid that has antimicrobial and moisturizing properties. It is used for the treatment of dry skin, burns, and wounds. It also has osmotic dehydrating properties and is used in the treatment of constipation.

Glycerin Uses:

• Constipation:
  • It is used to relieve occasional constipation.
• Mouth and throat irritation:
  • It is used for the temporary relief of minor discomfort and protection of irritated areas in the sore throat and sore mouth.

Glycerin Dose in Adults

Glycerin Dose in the treatment of Constipation:

• How much to use: For adults, use one suppository (a small thing you put in your bottom) each day when you need it or as your doctor tells you.

Glycerin Dose in the treatment of Mouth and throat irritation:

• How to use it: Put a one-inch strip of glycerin directly onto your tongue and inside your mouth whenever you feel the need.

Glycerin Dose in Childrens

Glycerin Dose in the treatment of Fecal impaction, rapid disempaction: Rectal:

If a baby or a child under 2 years is dealing with a severe blockage in their bowels and needs quick help, here's a simple explanation:

• How to use it: Give the child one pediatric suppository (a small thing you put in their bottom) once.

Glycerin Dose in the treatment of Constipation: Rectal: Suppository:

• For Children 2 to 5 years old: Use one pediatric suppository (a small thing you put in their bottom) once a day as needed or as your doctor tells you.
• For Children 6 years and older, including Adolescents: Use one adult suppository (a similar thing but a bit larger) once a day as needed or as your doctor instructs.

Glycerin Dose in the treatment of Mouth/throat irritation: Oral: Oral gel:

If children aged 2 years and older or teenagers are dealing with irritation in their mouth or throat, and you want to use glycerin to help, here's a simple explanation:

• How to use it: Apply a 1-inch strip of glycerin oral gel directly to their tongue and inside their mouth whenever they feel the need.

Glycerin Pregnancy Category: C

• Pregnancy is safe for glycerin suppositories. There is not much data so be cautious.
• You can use it for constipation or to treat nipple cracks while breastfeeding. However, you must apply the topical cream after breastfeeding.

Dose in Kidney disease:

No dosage adjustment recommended.

Dose in Liver disease:

No dosage adjustment recommended.

Side effects of Glycerin:

• Gastrointestinal:
  • Abdominal cramps
  • Rectal irritation
  • Tenesmus

Contraindications to Glycerin:

In the following circumstances, it should not be used:

• Patients who are bleeding per rectum must avoid rectal suppositories.
• Patients suffering from intestinal obstruction.

It is best to avoid prolonged use of laxatives.

Monitoring parameters:

Monitor the response. Observe the patient for abdominal pain, cramps, and dehydration.

How to administer Glycerin?

Oral Use:

• How to Apply: Put the gel on your tongue and around the inside and outside of your teeth and gums.
• Important Note: Don't rinse your mouth afterward.

Rectal Use:

• How to Insert: Put the suppository high up in the rectum.
• Important: Keep it inside for about 15 minutes; it doesn't have to melt completely to work.

Mechanism of action of Glycerin:

• This describes a substance that acts as an osmotic dehydrating agent, increasing osmotic pressure.
• It works by drawing fluid into the colon, which then stimulates bowel movements, leading to evacuation.

Onset of Action for Constipation:

• Suppository: It usually takes 15 to 30 minutes for the suppository to start working in cases of constipation.

Absorption:

• Rectal Absorption: Glycerin is poorly absorbed when applied in the rectum. This means it doesn't enter the bloodstream easily from that area.

International Brand Names of Glycerin:

• Fleet Liquid Glycerin Supp
• Pedia-Lax
• Sani-Supp Adult
• Sani-Supp Pediatric
• Adulax
• Babylax
• Bebegel
• Benlax
• Bulboid
• Computer Eye Drops
• Covonia
• Covonia Dry & Tickly Cough Linctus
• Cristal
• Czopki Glicerolowe
• Czopki Glicerynowe
• Dexeril
• Endura
• Estrin
• Farmino
• Finalina
• Fleet Baby Lax
• Fleet Babylax
• Formula Liquida Limpieza
• Gely
• Glicel
• Glicerina
• Glicerina Cinfa
• Glicerina Quimpe
• Glicero Microlismi
• Glicerol Vilardell
• Glicerolo
• Glicerolo Dynacren
• Glicerolo Sofar
• Glicerotens
• Glicev
• Glycelax
• Glycerol
• Glycerol ”Oba”
• Glycerotone
• Glycilax
• Glysup
• Gota PC
• Hidrate
• Jabon de glicerina
• Kalmo
• Kanova
• Kimos
• LASS
• Laxanova
• Laxolyne
• Laxovit
• Luxoral
• Micronema
• Milax
• Miniderm
• Nene-Lax
• Neutrobar
• Novas
• Obifax
• PC Grin
• Petit Drill
• Practomil
• Prolax
• V. Wash Soap Free Cleansing Liquid
• QV Flare
• QV Flare Up Cream
• Refenax Lagrimas
• RubieLax
• Slabinorm
• Supo Gliz
• Supo Kristal
• Supos Glicerina Mandri
• Suppositoria Glycerini
• Tixylix Baby Syrup
• Tixylix Toddler Syrup
• Verolax
• Vitrosups
• Vixorfit
• Xin Long
• Zen Care
• Zetalax

Glycerin Brand Names in Pakistan: