Mometasone, commonly known by its brand name Elocon among others, is a corticosteroid medication primarily used topically to treat various skin conditions. It belongs to a class of medications known as glucocorticoids or corticosteroids. These drugs have anti-inflammatory, anti-itching, and immunosuppressive properties.

Topical corticosteroids, such as mometasone furoate (Elocon), are used to treat skin disorders like eczema that respond to them.

Mometasone Furoate Uses:

• Corticosteroid-responsive dermatoses:
  • It is used to relieve the inflammatory and itchy symptoms of dermatoses that respond to corticosteroids. It is a topical corticosteroid of medium strength.

Read: Topical Hydrocortisone Cream, Ointment, Lotion Uses & Brands

Mometasone Furoate Dose in Adults:

Mometasone Furoate Dose in the treatment of Corticosteroid-responsive dermatoses:

• Put it on lightly.
• Don't cover the area with bandages or tight dressings.
• Stop using it once the skin gets better.
• If there's no improvement in 2 weeks, check with your doctor.
• For creams or ointments: Spread a small amount on the problem area every day.
• For lotion or liquid: Drop a little on the problem area every day.

Mometasone Furoate Dose in Children:

Note: Withhold treatment until you've gained control. If there is no improvement after two weeks, reevaluate the diagnosis.

Mometasone Furoate Dose in the treatment of Corticosteroid-responsive dermatoses:

• For cream or ointment:
  • Kids 2 years and older & teenagers: Put a thin layer on the problem skin every day. Don't use on kids for more than 3 weeks.
• For lotion or liquid:
  • Kids 12 years and older & teenagers: Drop a bit on the problem skin every day and rub it in gently.

Pregnancy Risk Factor C

• Animal studies have shown some issues when using topical corticosteroids during pregnancy.
• How much of the medicine gets into the bloodstream can vary based on skin health and if the area is covered.
• Pregnancy can also affect this.
• Most of the time, using these creams or ointments during pregnancy doesn't cause problems for the baby.
• But, if a mother uses strong versions in large amounts, there's a higher chance the baby might be born smaller than usual.
• If pregnant, it's better to use milder creams and not for a long time.
• It's also good to avoid putting them on parts of the body where the skin might absorb more medicine.
• Using these creams might also increase the chances of getting stretch marks during pregnancy.

Mometasone use during breastfeeding:

• It's not clear if using mometasone cream could lead to the medicine being in breast milk.
• But, when you put corticosteroids on your skin, only a little might get into the milk, unlike when you take them by mouth.
• Most experts think using corticosteroid creams while breastfeeding is okay.
• But, be careful about putting these creams directly on your breasts.
• A baby had issues when a strong corticosteroid was put on the nipple.
• So, it's alright to use these creams while breastfeeding, but be cautious and avoid using them on your breasts until you're done breastfeeding.

Mometasone Furoate Dose in Kidney Disease:

There are no dosage adjustments needed for renal impairment.

Mometasone Furoate Dose in Liver disease:

There are no dosage adjustments recommended for hepatic impairment.

Side Effects of Mometasone Furoate:

• Hematologic & Oncologic:
  • Bruise
• Central Nervous System:
  • Paresthesia
• Dermatologic:
  • Telangiectasia
  • Dermatologic Disorders
  • Dyschromia
  • Taut And Shiny Skin
  • Folliculitis
  • Bacterial Skin Infection
  • Epidermal Thinning
• Local:
  • Application Site Burning
  • Application Site Pruritus
• Gastrointestinal:
  • Xerostomia
• Endocrine & Metabolic:
  • Decreased Cortisol
  • Endocrine Disease

Frequency of side effects not defined:

• Dermatologic:
  • Furunculosis
  • Skin Atrophy
  • Acne Rosacea
  • Stinging Of The Skin
• Central Nervous System:
  • Tingling Of Skin

Contraindications to Mometasone Furoate:

If you're allergic to mometasone furoate or anything else in the medicine, don't use it.

Even though we don't have full details, if you're allergic to one type of corticosteroid, you might be allergic to others because they can be similar.

In Canada, there are extra warnings:

• Don't use on skin with viral problems (like cold sores or chickenpox), fungal or bacterial infections, or parasites.
• Don't use on skin showing signs of TB or syphilis, or on skin reactions after vaccinations.
• Avoid using on acne, rosacea, or itchy skin without visible redness.
• Don't put in your eyes.
• Don't use with tight bandages.

Warnings and precautions

Suppression of the adrenals:

• Using this medicine might affect your adrenal glands, which help produce certain hormones.
• This can be more likely in kids or if someone uses a lot of the medicine for a long time.
• If the adrenal glands don't work properly, it might lead to a serious condition called adrenal crisis.

Contact dermatitis:

• Sometimes, using this medicine can lead to a skin reaction called allergic contact dermatitis.
• This might show up as skin not getting better or even getting worse.
• If your skin gets irritated, stop using the medicine and treat the irritation.

Immunosuppression:

• Using this medicine for a long time can lower your skin's defense against germs.
• This can lead to fungal or bacterial infections.
• If you get a skin infection and it doesn't get better even after using the right treatments, you should stop using this medicine.

Ocular effects

• Using creams like mometasone on your skin can raise the chance of certain eye problems, like cataracts and glaucoma.
• Keep an eye out for any changes in your vision.
• Make sure the cream doesn't get into your eyes.

Systemic effects

• Creams like this can sometimes get into your bloodstream through the skin.
• If they do, they can cause body-wide symptoms, like those seen in Cushing's syndrome, high blood sugar, or sugar in urine.
• You're more likely to absorb more if you cover the area with tight bandages, put it on broken skin, or apply it to big parts of your body.

Mometasone Furoate (topical): Drug Interaction

Monitoring parameters:

• Long-term or heavy use can affect adrenal glands.
• Tests to check:
  • ACTH stimulation test
  • Morning plasma cortisol test
  • Urinary free cortisol test

Treatment Response

• Check how the skin is healing or responding to the medicine.

Eye Changes

• This medicine can affect the eyes.
• Watch out for any changes in vision or eye discomfort.

How to administer Mometasone Furoate?

• Use only a small amount.
• Stay away from sensitive areas like inside the nose, mouth, eyes, face, underarms, and private parts (including baby diaper areas).
• Don't put any wraps or bandages over the treated area.

Specific Instructions:

• For creams or ointments: Spread a thin layer on the problem skin.
• For lotions or liquids: Drop a bit on the skin and gently rub it in until it's gone.

Mechanism of action of Mometasone Furoate:

• They reduce inflammation, itching, and narrow blood vessels.
• They slow down or stop the body from releasing inflammation-causing chemicals.
• They work by triggering proteins (like lipocortins) that prevent the release of an inflammation-related substance called arachidonic acid.
• Mometasone is mid-strength compared to other corticosteroids.

How Much Gets Absorbed:

• Cream: Only 0.4% of it goes into the skin. If the skin is inflamed, more might get absorbed.
• Lotion, ointment, solution: About 0.7% gets absorbed. Again, if there's inflammation, this can be higher.

International Brand Names of Mometasone Furoate:

• Elocon
• Allerta Dermatec
• Allerzone
• Avocom
• Borgasone
• Cortimon
• Dermacortine
• Dermome
• Dermotasone
• Dermovel
• Ecural
• Eczaderm
• Elica
• Elicort
• Elisone
• Elna
• Elocom
• Elocon
• Elocon Cream
• Elocon Ointment
• Elocortin
• Elomet
• Eloskin
• Eloson
• Elosone
• Flogocort
• Inpura
• Intercon
• Konex
• Lavelia Lotion
• Loksin
• Lomeane
• Mefurosan
• Melocon
• Meloderm
• Melomet
• Mesone
• Metaz
• Metson
• Mezo
• Mofulex
• Mofuroate
• Momate
• Momecort
• Momed
• Momederm
• Momet
• Monovel
• Moricort
• Mosone
• Motaderm
• Moteson
• Mtaz
• Novasone Cream
• Novasone Lotion
• Novasone Ointment
• Soneta
• Suqi
• Topcort
• Vizomet
• Zatamil
• Zynovate

Mometasone Furoate Brand Names in Pakistan: