Tolnaftate - Uses, Dose, Side effects, MOA, Brands

Tolnaftate is an antifungal medicine that is used for topical application. It is used to treat an athlete's foot infection, jock itch, and ringworm infections.

Tolnaftate Uses:

  • Tinea pedis, tinea corporis, and tinea cruris are all conditions it is used to treat.
  • It is also used in the prevention of tinea pedis infection.

Tolnaftate Dose in Adults

Tolnaftate Dose in the treatment of Tinea pedis:

  • Treatment:

    • Apply topically twice a day for 4 weeks
  • Prevention:

    • Apply topically once or twice a day.

Tolnaftate Dose in the treatment of Tinea corporis:

  • Apply topically two times a day for four weeks.

Tolnaftate Dose in the treatment of Tinea cruris:

  • Apply topically two times a day for two weeks.

Tolnaftate Dose in Children

Tolnaftate Dose in the treatment of Tinea pedis:

  • Treatment:

    • Children 2 years old and older as well as teenagers:

      • Apply topically two times a day for 4 weeks
  • Prevention:

    • Children 2 years old and older as well as teenagers:

      • Apply externally once or twice a day.

Tolnaftate Dose in the treatment of Tinea corporis:

  • Children 2 years of age or older and Adolescents:

    • Apply topically two times a day for four weeks.

Tolnaftate Dose in the treatment of Tinea cruris:

  • Children older than 2 years of age and Adolescents:

    • Apply externally two times a day for two weeks.

Pregnancy Category: N

  • It has not been classified as an FDA pregnancy risk category. It has not been tested in human or animal pregnancy studies.
  • Manufacturers advise weighing the advantages and disadvantages of medication therapy for mothers and infants.

Use during breastfeeding:

  • It has not yet been tested in lactating mothers. 
  • It's critical to consider both the advantages and disadvantages of the mother's drug exposure.

Dose in Kidney Disease:

  • The manufacturer's labelling does not provide any dose modifications.
  • The low level of systemic absorption makes dose modification unlikely.

Dose in Liver disease:

  • The manufacturer's labelling does not mention dose modifications.
  • The low level of systemic absorption makes dose modification unlikely.

Side effects of Tolnaftate:

  • Dermatologic:

    • Contact dermatitis
    • Pruritus
    • Stinging of the skin
  • Local:

    • Irritation

Contraindications to Tolnaftate:

The manufacturer's label does not mention any contraindications.

Warnings and precautions

  • Irritation

    • Some patients may experience allergic reactions to the drug. If symptoms of allergic reaction are detected, the treatment might need to be stopped.

Monitor:

No monitoring parameters have been mentioned. Monitor for clearance and the response to treatment.

How to administer Tolnaftate?

Topical:

  • Only topical application (external usage) is recommended. Eye contact should be avoided.
  • Before applying the spray, wash the area and let it dry or dry the area with a tissue or a clean towel.
  • Apply the medicine to spaces between the toes in patients with tinea pedis infection.
  • The aerosol and aerosol powder should be shaken well before using them.

Mechanism of action of Tolnaftate:

It distorts the hyphae, and it inhibits fungal mycelia growth in susceptible fungi.

The beginning of action:

  • 24-72 hours

International Brand Names of Tolnaftate:

  • Athletes Foot Spray
  • Dr Gs Clear Nail
  • FungiGuard
  • Fungoid-D
  • Jock Itch Spray
  • LamISIL AF Defense
  • Medi-First AntiFungal
  • Tinactin
  • Mycocide Clinical NS
  • Podactin
  • The Treatment Formula 3
  • Tinactin Jock Itch
  • Tinaspore
  • Tolnaftate Antifungal
  • Scholl Athlete's Foot Powder
  • Aftate
  • Creobic
  • Hi-Alarzin
  • Pitrex
  • Scholl Athlete's Foot Spray
  • Athlete's Foot
  • Chinofungin
  • SeparinScholl Athlete's Foot
  • Solufungin
  • Sorgoa
  • Tinactin Deodorant
  • Sporiline
  • Tinactin
  • Tinaderm
  • Tinaderm M
  • Digifungin
  • Ezon-T
  • Focusan
  • Tinaderme
  • Tinafate
  • Tinatox
  • Tineacure
  • Tineafax
  • Tolfet
  • Tolnadem
  • Tolnaderm
  • Tolsol
  • Tonaf

Tolnaftate Brand Names in Pakistan:

No Brands Available in Pakistan.

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