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Dear Readers! I started this blog when my daughter was in the NICU. She had ventriculitis. Her CSF report grew E.coli. But, she was injected Teicoplanin directly into her brain. The doctors made two errors here:

Teicoplanin is for gram-positive bacteria only. It does not treat E.coli.
Teicoplanin is not for intraventricular use. The manufacturer strongly discourage injecting Teicoplanin into the brain.

My daughter bled into the brain. She lived for another two years and ultimately died.

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Trichloroacetic acid (Tri-Chlor) - Uses, Dose, MOA, Brands, Side effects

Trichloroacetic acid (Tri-Chlor) is a strong acid and a derivative of acetic acid. It is utilized in the treatment of patients with genital and anal warts.

Trichloroacetic acid Uses:

Condylomata:
- It is used to treat external anal and genital warts (condylomata).
- The regulatory authorities recommend that the drug should only be used by healthcare providers. Self-administration is not recommended. Furthermore, it has not been extensively investigated and the benefits should weigh the risks when treating a patient.

Trichloroacetic acid (Tri-Chlor) Dose in Adults

Trichloroacetic acid (Tri-Chlor) Dose in the treatment of Condylomata:

It is applied topically over the lesions by a healthcare provider. The solution is then allowed to dry frost on the tissue before the patient is allowed to move, sit or stand. Lesions that have not responded by be applied the solution at weekly intervals.

Use in children:

Not indicated.

Use in pregnancy and lactation:

Preferably use other medicines, however, it has been found to effectively treat genital condylomas in pregnant women.

Dose in kidney disease:

No dosage adjustment is recommended in patients with kidney disease

Dose in liver disease:

No dosage adjustment is recommended.

Side effects of Trichloroacetic acid (Tri-Chlor):

Because of its caustic effects, it can result in a mild to moderate degree of skin burn, irritation, ulceration, skin swelling, and pain.

Contraindications and Warnings:

Patients who are allergic to the drug should avoid using it.
Severe allergic reactions may occur and manifest as shortness of breath, hives, urticaria, wheezing, and difficulty in breathing.

Monitoring parameters:

Monitor the response to treatment.

How to administer Trichloroacetic acid (Tri-Chlor)?

It is applied topically by a healthcare provider.
It is less viscous and the viscosity of the solution matches that of water.
Caution should be advised when applying the drug.
Large amounts may result in damaging the surrounding tissue and skin.
In case the normal skin gets exposed to it or the skin gets damaged, sodium bicarbonate may be applied to the burned area.
Patients may also get some relief by washing the area with water and liquid soap or talc.

Trichloroacetic acid (Tri-Chlor) MOA:

It is an analog of acetic acid.
It is a strong acid and when applied to tissues such as anal and genital warts, it causes mild degrees of burns and necrosis of the skin.

International Brands of Trichloroacetic acid:

Tri-Chlor
Acido Tricloroacetico
CL3 Bruciaporri

Trichloroacetic acid Brand Names in Pakistan:

No Brands Available in Pakistan.