Beta Blockers Use in Patients with Chronic Liver Disease

Author: owner     Published: 2 years ago 2 Replies

Which Beta-Blocker should be preferred in patients with Chronic Liver Disease?

Propanolol, carvedilol,Nadolol,Timolol

Maria, 2 years ago

 Nadolol  and propranolol are two nonselective beta blockers that are used for primary prophylaxis against variceal hemorrhage. We typically use nadolol (since it can be given once daily) at a starting dose of 40 mg per day. Propranolol is usually started at a dose of 20 mg twice a day

 Carvedilol is a potent beta blocker that also has mild anti-alpha 1 adrenergic activity. It is an alternative to nonselective beta blockers for routine prophylaxis. In addition to reducing portal venous inflow through nonselective beta blockade, the anti-alpha 1 adrenergic activity leads to reduced hepatic vascular tone and hepatic resistance. This in turn leads to a further reduction in portal pressure. However, it also can result in significant drops in mean arterial blood pressure (average decrease of 23 percent in one study), which may be poorly tolerated by patients with cirrhosis

Dr. Adnan Khan, 2 years ago

Login to Reply

Money Back Guarantee
We return Money in 24 Hours

Secure online payment
We possess SSL / Secure Certificate

12/7 customer support
Well-trained & Supportive team

PMDC Verified Doctors
Authentic & updated information

emedz.net

Book Online and In-clinic appointment with your doctor. Consult via Video chat and get a prescription. Ask any question in the "Forum" section and get a detailed answer. Discuss your health issues.

Connect with us

Copyright @ 2024 - All Rights Reserved Reproduction of material from any pages without permission is strictly prohibited.