Biotin (vitamin H) as an OTC Dietary Supplement

Biotin or vitamin H is used as over the counter dietary supplement. It is commonly used as a dietary supplement for hair growth, brittle nails, neuronal function, conjunctivitis, and dermatitis. Deficiency of biotin may result in developmental delay, hypotonia, seizures, alopecia, dermatitis, coma, hyperammonemia, rash, and ketoacidosis. Order Biotin 

Biotin (Vitamin H) Dose in Adults

Biotin as a dietary supplementation (OTC labeling):

    • One tablet or capsule daily

Biotin (Vitamin H) Dose in Childrens

Use as Adequate intake:

  • Infants:
    • 1 - 6 months:
      • 5 mcg/day
    • 7 - 12 months:
      • 6 mcg/day
  • Children and Adolescents:
    • 1 - 3 years:
      • 8 mcg/day
    • 4 - 8 years:
      • 12 mcg/day
    • 9 - 13 years:
      • 20 mcg/day
    • 14 - 18 years:
      • 25 mcg/day

Use in the treatment of symptomatic Biotinidase deficiency:

  • Infants, Children, and Adolescents:
    • 5 - 20 mg orally once a day.

Pregnancy Risk Factor: B

  • It is a water soluble vitamin and crosses the placental barrier.

Vitamin H use during breastfeeding:

  • It is excreted in breastmilk and may be continued during lacatation.

Biotin (Vitamin H) Dose in Renal Disease:

  • Adjustment in dose has not been recommended by the manufacturer in patients with kidney disease.

Biotin (Vitamin H) Dose in LIver Disease:

  • Adjustment in dose has not been recommended by the manufacturer in patients with liver disease.

Side Effects of Biotin (Vitamin H)

Adverse effects have not been listed in the manufacturer's labeling.

Contraindication to Biotin (Vitamin H)

Warnings & Precautions

  • Lab tests:
    • Patients taking high levels of biotin may have some laboratory errors.
    • Biotin technology can be used to test certain commonly ordered tests such as Troponin. It also allows for the testing of hormones using biotin to bind specific proteins.
    • If the pateints clinical symptms and the lab test result do not correspond, biotin interference should be considered as a possible source of error (FDA medicine watch - Biotin interfernece)

Monitoring Parameters:

None required.

How to take Biotin (Vitamin H)?

  • It is administered orally without regard to meals (but may be preferable to take it with meals).

Mechanism of action of Biotin (Vitamin H):

It functions as a coenzyme, participates in the catabolism and metabolism of leucine, propionate metabolism, and the carboxylation, transcarboxylation,  and decarboxylation events for gluconeogenesis and lipogenesis (the production of fatty acids).

International brand names of Biotin (Vitamin H):

  • Aminosam
  • Bioak
  • Biotiforte
  • Biotin A
  • Biotin Forte
  • Biotinol
  • Curatin
  • Deacura
  • HAARNA mono Biotin
  • Hiotin
  • Medobiotin
  • Untral

Biotin brands in Pakistan:

Syrup 5 Mcg/5ml

Honeyplex Mediaims Pharmaceuticals

Syrup 25 Mcg/5ml

Multina-33 Helicon Pharmaceutek Pakistan (Pvt) Ltd.

Syrup 300 Mcg/5ml

Blomic Bloom Pharmaceuticals (Pvt) Ltd.
Sangobion Merck Private Ltd.
Siron Dr. Raza Pharma (Private) Limited

Tabs 0.1 Mg

Hepatovit Himont Pharmaceuticals (Pvt) Ltd.

Tabs 0.2 Mg

Fiterna Shawan Pharmaceuticals
Pregnovit Himont Pharmaceuticals (Pvt) Ltd.

Tabs 15 Mcg

Dynamin-V Standpharm Pakistan (Pvt) Ltd.
Engor English Pharmaceuticals Industries
Hicap-Ss Himont Pharmaceuticals (Pvt) Ltd.
Multicap-M Flow Pharmaceuticals (Pvt) Ltd.
Theragran-M Glaxosmithkline
Vitalet-M Paramount Pharmaceuticals

Tabs 30 Mcg

Engran GlaxoSmithKline
Evival English Pharmaceuticals Industries
Once A Day Consolidated Chemical Laboratories (Pvt) Ltd.
Quantum Gold Martindale Health Care
Quantum Super Martindale Health Care
Therin-M Super Martindale Health Care

Tabs 45 Mcg

Stresstabs Pfizer Laboratories Ltd.
Theragran Stress Glaxosmithkline

Tabs 0.15 Mg

Berocca Bayer Health Care
Centrum Pfizer Laboratories Ltd.
Combiplex Forte Lahore Chemical & Pharmaceutical Works (Pvt) Ltd
Mazivit M Mass Pharma (Private) Limited
Oravit-H Popular Chemical Works (Pvt) Ltd.
Revitale M GlaxoSmithKline
Revitale-B GlaxoSmithKline

Tabs 250 Mcg

Nutrition-12 Werrick Pharmaceuticals

Tabs 300 Mcg

Hicap-M Himont Pharmaceuticals (Pvt) Ltd.
Neurovit-M Unipharma (Pvt) Ltd.

Tabs 600 Mcg

Epivite Glaxosmithkline

Caps 0.2 Mg

Pilfood Hilton Pharma (Pvt) Limited

Caps 45 Mcg

Perfectil Acti-Med Pharma (Pvt) Ltd.

Caps 50 Mcg

Vivioptal Agp (Private) Ltd.

Caps 0.5 Mcg

Sevenseas Mvm Alina Combine Pharmaceuticals (Pvt) Ltd.

Dragees 0.1 Mg

Litrison Bayer Health Care

Dragees 0.15 Mg

Becozym Forte Bayer Health Care

Dragees 0.25 Mg

Supradyn-N Bayer Health Care


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