Derman is the brand name of the drug that contains Undecylenic acid and derivatives. It has antifungal and astringent properties. it is utilised for the therapy of:
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Jock itch (tinea cruris)
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Ringworm (tinea corporis)
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Athlete's foot (tinea pedis)
Derman Dose in Adults
Derman Dose in the treatment of Tinea pedis and tinea corporis:
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- Two times each day for four weeks, use as a topical solution.
Derman Dose in the treatment of Tinea cruris (spray only):
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- Two times each day for two weeks, use as a topical solution.
Derman Dose in Children
Derman Dose in children for the treatment of Athlete's foot (tinea pedis):
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Children older than 2 years of age:
- Apply as a topical solution two times a day for four weeks.
Derman Dose in children for the treatment of Ringworm (tinea corporis) infection:
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Children older than 2 years of age:
- Apply as a topical solution two times a day for four weeks.
Use in Pregnancy and lactation:
Topical applications of the drug other than over the breast or nipple may be safely used in pregnant and lactating mothers.
Dose in Kidney disease:
The manufacturer has not recommended any adjustment in the dose in patients with kidney disease
Dose in liver disease:
The manufacturer has not recommended any adjustment in the dose in patients with liver disease.
Side effects of Derman:
Topical application may result in hypersensitivity reactions causing redness and itching.
Contraindication to Derman (Undecylenic acid and derivatives) includes:
Children under two years old should not use OTC medicines to treat diaper rash.
Warnings and precautions
- Self-medication (OTC):
- OTC medicines should not be applied to the scalp. Avoid contact with the eyes.
- A healthcare provider should be consulted if irritation persists or the condition doesn't improve within four weeks.
Monitoring Parameters:
- No monitoring parameters are required.
- The response to treatment should be assessed after a few days.
- In non-responders, other potent antifungal agents for topical or oral use may be tried.
How to apply Derman (Undecylenic acid and derivatives)?
- It is available for topical application only.
- Apply a small coating to the skin that is dry and clean. When applied to the scalp or nails, it is ineffective.
Topical application for Tinea pedis:
- It should be applied between the toes.
- Encourage the patient to wear comfortable, well-ventilated footwear.
- The patient should be advised to change the shoes and socks at least once a day.
Mechanism of action of Derman (Undecylenic acid and derivatives):
It is a fungistatic fatty acid that may include zinc. It reduces irritation and roughness by having an astringent effect.
International Brands of Undecylenic acid and derivatives:
- BioRx Sponix Anti-Fungal
- Elon Dual Defense Anti-Fungal
- Fungi-Nail Toe & Foot
- Fungi-Nail
- Gordochom
- Hongo Cura Anti-Fungal
- Myco Nail A
- Derman
- Desenex
- Micotex
- Mycota
Undecylenic acid Brand Names in Pakistan:
No brands are available in Pakistan.