Hydrogen peroxide (H₂O₂) is a chemical compound composed of two hydrogen atoms and two oxygen atoms. It is a pale blue liquid that appears colorless in a dilute solution, and it has a slightly more viscous consistency than water.

Hydrogen Peroxide antiseptic solution is used to cleanse wounds, minor cuts, and abrasions. It is also used as an oral gel or a mouthwash to remove oral secretions and treat lesions in the oral cavity.

Hydrogen peroxide Antiseptic Solution Uses:

• As an antiseptic for minor dermal abrasions:
  • It can be used to treat localized infections, suppurating ulcers, and wounds.
  • Inflammatory disorders of the external auditory canal may be treated with it.
• Seborrheic keratosis (topical solution 40% only):
  • Seborrheic keratosis patients are treated with the topical 40% solution.
• Mouth, gum, or dental irritation and for the removal of oral secretions:
  • You can gargle or use hydrogen peroxide as a mouthwash.

Hydrogen Peroxide Antiseptic Solution Dose in Adults

Hydrogen Peroxide Antiseptic Solution Dose in the Removal of oral secretions:

If you need to clean your mouth or have some kind of issue in your mouth, you can use hydrogen peroxide. Get a solution that is 3%, which is a bit stronger than the one you might have at home.

Here's what you do:

• Dilute a small amount of the solution.
• Swish it around in your mouth, making sure it touches the problem area, for at least 1 minute.
• Spit it out.

You can do this up to four times a day, after you eat and before bedtime. This helps keep your mouth clean and might help with any issues you're having.

Minor cutaneous abrasion and hydrogen peroxide antiseptic solution dosage:

If you need to clean your mouth or have some kind of issue in your mouth, you can use hydrogen peroxide. Get a solution that is 3%, which is a bit stronger than the one you might have at home.

Here's what you do:

• Dilute a small amount of the solution.
• Swish it around in your mouth, making sure it touches the problem area, for at least 1 minute.
• Spit it out.

You can do this up to four times a day, after you eat and before bedtime. This helps keep your mouth clean and might help with any issues you're having.

Hydrogen Peroxide Antiseptic Solution Dose in the treatment of Mouth, gum, or dental irritation:

If your mouth, gums, or teeth are bothering you, you can use hydrogen peroxide in two different forms:

• Oral Rinse (1.4%):
  • Take 10 mL of the oral rinse.
  • Swish it around your mouth, especially over the sore or irritated area, for at least 1 minute.
  • Spit it out.
  • You can do this up to four times a day, after meals and before bedtime.
• Oral Gel (1.7%):
  • Apply several drops of the oral gel to the area that's bothering you.
  • Let the gel stay on that spot for at least 1 minute.
  • Spit it out.
  • You can use the gel up to four times a day, after meals and at bedtime.

This can help with the irritation and make your mouth feel better. But, as always, don't use too much, and if you're unsure, it's a good idea to check with someone who knows about these things.

Dose of hydrogen peroxide antibiotic solution for seborrheic keratoses (raised):

If you have raised seborrheic keratoses (skin growths), a stronger form of hydrogen peroxide can be used. Here's how it works:

• Get a 40% topical solution.
• Apply it to the raised lesions (the growths on your skin) four times during one visit to the doctor's office.
• Space out each application by about 1 minute.

If, after about three weeks, the treated growths haven't completely gone away, you might need to repeat the treatment.

Hydrogen Peroxide Antiseptic Solution Dose in Children

Hydrogen Peroxide Antiseptic Solution Dose as Antiseptic and for minor dermal abrasion:

If a child is 2 years old or older and has a small cut or scrape, you can use hydrogen peroxide to help it heal. Here's what to do:

• Get a solution that is 3%, which means it's not too strong.
• Apply a little bit to the cut or scrape.
• Do this once to three times a day.

This helps to keep the wound clean and might help it get better faster. Just be careful not to use too much, and if you're not sure, it's always good to ask someone for help.

Hydrogen Peroxide Antiseptic Solution Dose in the Removal of oral secretions:

If a child is 2 years or older and needs to clean their mouth or has some trouble in their mouth, you can use hydrogen peroxide. Here's how:

• Get a solution that is 3%, not too strong.
• Dilute a little bit of it.
• Swish it around in the mouth, making sure it touches the problem area, for at least 1 minute.
• Spit it out.

They can do this up to four times a day, after meals and before bedtime. This helps keep the mouth clean and might make any issues they're having feel better.

Hydrogen Peroxide Antiseptic Solution Dose in the treatment of Mouth, gum, or dental irritation:

If a child is 2 years or older and is dealing with irritation in the mouth, gums, or teeth, hydrogen peroxide can be used in two forms:

• Oral Rinse (1.4%):
  • Take 10 mL of the oral rinse.
  • Swish it around the mouth, especially over the sore or irritated area, for at least 1 minute.
  • Spit it out.
  • This can be done up to four times a day, after meals and before bedtime.
• Oral Gel (1.7%):
  • Apply several drops of the oral gel to the area that's bothering them.
  • Let the gel stay on that spot for at least 1 minute.
  • Spit it out.
  • The gel can be used up to four times a day, after meals and at bedtime.

This can help with the irritation and make the mouth feel better.

Pregnancy And Lactation Implications:

The topical application may be used in pregnant and lactating women avoiding application over the breast and nipple in lactating women.

Use in patients with hepatic impairment:

The topical solution may be applied in patients with liver disease.

Use in patients with renal impairment:

In individuals with renal impairment, topical solutions may be used.

Common Side Effects of Hydrogen Peroxide Antiseptic Solution:

• Local:
  • Skin Edema
• Dermatologic:
  • Desquamation
  • Crusted Skin
  • Erythema
  • Stinging Of The Skin
  • Pruritus
  • Hypopigmentation
  • Severe Erythema
  • Hyperpigmentation
  • Skin Vesicle
  • Skin Erosion

Less Common Side Effects of Hydrogen Peroxide Antiseptic Solution:

• Dermatologic:
  • Dermal Ulcer
  • Cicatrix Of Skin
  • Skin Atrophy

Contraindications to Hydrogen Peroxide Antiseptic Solution:

• Abscesses: Don't use hydrogen peroxide if you have an abscess.
• Topical Solution (40%): There are no specific reasons mentioned by the manufacturer that say you can't use this solution for its intended purposes.

Warnings and precautions

Dermatologic reactions

• If you use this treatment for seborrheic keratoses on your skin, be aware that some skin reactions might happen in that area, like redness or sores.
• In serious cases, the skin can get really damaged, forming blisters or scars.
• Don't try the treatment again until your skin has fully healed from any reaction caused by the first treatment.
• Always be cautious and give your skin time to recover before attempting another round of treatment for those raised skin growths.

Monitoring Parameters:

None mentioned.

How to use Hydrogen Peroxide Antiseptic Solution?

Topical: Dermal Application (3% Solution/Spray):

• Don't Shake: Don't shake the container.
• Open Carefully: Open the container away from your face.
• Clean First: Clean the affected area before applying.
• Bandage Option: After the solution dries, you can cover it with a sterile bandage.
• Dilution Reminder: Solutions with a concentration higher than 3% can irritate, so dilute them before use.

Topical: Dermal Application (40% Solution):

• Topical Use Only: Only use on your skin, not in your mouth, eyes, or internally.
• Preparation: Clean the affected area with an alcohol wipe as per the manufacturer's instructions.
• Application Process: Apply the solution directly to the lesion, covering it evenly without excess dripping. Don't use on open or infected lesions. Repeat the application three more times, one minute apart.

Topical: Oral Application (Removal of Oral Secretions - 3% Solution):

• Mix with Water: Mix equal parts of the 3% solution with water.
• Swish and Spit: Swish it around your mouth over the affected area for at least 1 minute, then spit it out.

Topical: Oral Application (Mouth, Gum, or Dental Irritation):

• Oral Rinse (1.4%): Swish around the mouth over the affected area for at least one minute, then spit it out.
• Gel (1.7%): Apply to the affected area(s) of the mouth. Let it stay for at least 1 minute, then spit it out. Remember, these are for topical use only, so don't swallow them.

Mechanism of action of Hydrogen Peroxide Antiseptic Solution:

Antiseptic Oxidant: Hydrogen peroxide is like a germ-fighting cleaner that releases oxygen and water when it comes in contact with substances like serum or tissue catalase. It helps clean and disinfect.

Treatment for Seborrheic Keratosis: Even though we use hydrogen peroxide to treat seborrheic keratosis (a type of skin growth), we're not exactly sure how it works. The exact way it helps isn't known, but it seems to be effective in dealing with these skin growths.

Duration of Action:

• Hydrogen peroxide only works for as long as you see it bubbling.
• Once the bubbling stops, its action is done.

Absorption:

• The body doesn't absorb hydrogen peroxide.
• It does its job externally and doesn't get inside the body.

International Brand Names of Hydrogen peroxide antiseptic solution:

• Eskata
• Perox-A-Mint
• Debrox
• Dentex
• Peroxyl Spot Treatm
• GoodSense Hydrogen Peroxide
• Aosept Plus
• Brite Smile Gel
• Confosept Eau Oxygen
• Confosept Zuurstofwater
• Crystacide
• Eau Oxygenee
• Hyperoxi
• Microcid
• Parkon
• Perakne
• Peroxid Vodika
• Peroxita CRM
• Peroxygel
• Peroxyl
• Trinity White Gel
• Zoom 2 White Gel

Hydrogen peroxide Brand Names in Pakistan: