What are the differences between Glargine U-100 (Lantus) and Glargine U-300 (Toujeo)?
| Glargine U 300 | Glargine U 100 |
| Provides consistent and prolonged insulin exposure compared with insulin Glargine 100 resulting in blood glucose control that lasts well beyond 24 hours | insulin exposure less as compared to glargine 300 |
| Stable 24 hours glycemic coverage as a result of low fluctuation and high reproducibility of insulin exposure | increased fluctuation compared to glargine 300 |
| Less risk of nocturnal hypoglycemia | risk greater s compared to insulin glargine 300 |