Olmesartan unique side effect

Author: Ali Sufyan     Published: 3 years ago 1 Replies

Give unique side effect of Olmesartan not reported with other Angiotensin receptor blockers?

Olmesartan enteropathy

Sprue like enteropathy characterized by chronic diarrhea and weight loss. May develop after months to years of drug initiation.

Intestinal Biopsy: Villous atrophy

Treatment: Exclude other etiologies, discontinue and shift to other antihypertensive

Reference: 

1) Ianiro G, Bibbò S, Montalto M, Ricci R, Gasbarrini A, Cammarota G. Systematic review: sprue‐like enteropathy associated with olmesartan. Alimentary pharmacology & therapeutics. 2014 Jul;40(1):16-23.

2) Rubio-Tapia A, Herman ML, Ludvigsson JF, Kelly DG, Mangan TF, Wu TT, Murray JA. Severe spruelike enteropathy associated with olmesartan. InMayo clinic proceedings 2012 Aug 1 (Vol. 87, No. 8, pp. 732-738). Elsevier.

Ali Sufyan, 3 years ago

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