Disclaimer Notice:

Dear Readers! I started this blog when my daughter was in the NICU. She had ventriculitis. Her CSF report grew E.coli. But, she was injected Teicoplanin directly into her brain. The doctors made two errors here:

Teicoplanin is for gram-positive bacteria only. It does not treat E.coli.
Teicoplanin is not for intraventricular use. The manufacturer strongly discourage injecting Teicoplanin into the brain.

My daughter bled into the brain. She lived for another two years and ultimately died.

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Topical Urea - Uses, Brands, Side effects

Topical Urea dissolves the hyperkeratotic intracellular matrix resulting in the softening of the hard skin. It promotes the healing and debridement of hyperkeratotic skin surface lesions, which is how it is used to treat hyperkeratotic skin lesions. It is especially helpful for skin diseases when eschar development, necrotic tissue, fibrinous or purulent waste, or local infection prevent healing. Additionally, it is applied to various hyperkeratotic skin diseases, including:

Corns and calluses
Damaged, ingrown, and devitalized nails.
Dermatitis
Psoriasis
Dry and rough skin
Skin cracks and fissures
Xerosis
keratosis
Ichthyosis
Eczema
keratoderma

Topical Urea Dose in Adults

Topical Urea Dose in the treatment of Hyperkeratotic conditions:

Apply over the hyperkeratotic area 1-3 times a day.

Topical Urea Dose in Children

Refer to the adult dose. The safety and efficacy of urea in children have not been established.

Pregnancy Risk Factor B/C

It has not yet been tested in pregnant women.
However, there have been no clinically significant adverse side effects from animal reproduction studies.

Urea use during breastfeeding:

Lactating mothers should not use it as the excretion into breast milk is unknown.

Topical Urea Dose in Renal Disease:

Adjustment in the dose for topica application of urea is not required in patients with renal disease.

Topical Urea Dose in Liver Disease:

Adjustment in the dose for topical application of urea is not required in patients with liver disease.

Side effects of topical urea:

Central nervous system:
- Transient stinging of the skin
Dermatologic:
- Burning sensation of skin (transient)
- Pruritus (transient)
Local:
- Local irritation

Contraindication to Topical Urea Include:

Urine or any other component of the formulation can cause severe allergic reactions. Avoid contact with infected, irritated or open skin wounds.

Warnings and precautions

Reactions to skin:
- Some brands may cause photosensitivity by topical application.
- It is possible to protect your skin and avoid sun exposure for at most one week after starting the treatment.

Monitor:

Monitor the response to therapy.

How to apply topical Urea?

It is massaged until fully absorbed after being applied to the afflicted region.
The affected area may be covered with an adhesive bandage or gauze piece or a plastic fill.
Prior to the application, the lotion, foam, and suspension are shaken well.